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Revenues
9 Months Ended
Sep. 30, 2023
Revenue from Contract with Customer [Abstract]  
Revenues Revenues
We operate in one business segment: human therapeutics. Therefore, results of our operations are reported on a consolidated basis for purposes of segment reporting, consistent with internal management reporting. Revenues by product and by geographic area, based on customers’ locations, are presented below. The majority of ROW revenues relates to products sold in Europe.
Revenues were as follows (in millions):
Three months ended September 30,
20232022
U.S.ROWTotalU.S.ROWTotal
Prolia$673 $313 $986 $590 $272 $862 
ENBREL1,026 1,035 1,086 20 1,106 
XGEVA374 145 519 363 132 495 
Otezla462 105 567 529 98 627 
Repatha183 223 406 142 167 309 
Nplate322 97 419 162 126 288 
KYPROLIS231 118 349 217 101 318 
Aranesp107 216 323 128 230 358 
EVENITY214 93 307 136 65 201 
Other products(1)
1,099 538 1,637 1,113 560 1,673 
Total product sales(2)
$4,691 $1,857 6,548 $4,466 $1,771 6,237 
Other revenues355 415 
Total revenues$6,903 $6,652 
Nine months ended September 30,
20232022
U.S.ROWTotalU.S.ROWTotal
Prolia$1,987 $954 $2,941 $1,783 $853 $2,636 
ENBREL2,645 37 2,682 2,965 54 3,019 
XGEVA1,145 440 1,585 1,122 408 1,530 
Otezla1,251 308 1,559 1,366 306 1,672 
Repatha592 626 1,218 461 502 963 
Nplate744 347 1,091 474 364 838 
KYPROLIS699 354 1,053 626 296 922 
Aranesp345 698 1,043 397 676 1,073 
EVENITY570 272 842 376 186 562 
Other products(1)
3,424 1,639 5,063 3,379 1,655 5,034 
Total product sales(2)
$13,402 $5,675 19,077 $12,949 $5,300 18,249 
Other revenues917 1,235 
Total revenues$19,994 $19,484 
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(1)    Consists of product sales of our non-principal products as well as sales in prior periods of our divested Bergamo and Gensenta subsidiaries.
(2)    Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2023 and 2022.