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Goodwill and other intangible assets (Identifiable Intangible Assets) (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Finite-Lived Intangible Assets [Line Items]      
Gross carrying amounts $ 35,615   $ 35,596
Accumulated amortization (21,231)   (20,525)
Other intangible assets, net 14,384   15,071
Gross carrying amount 36,624   36,605
Accumulated amortization (21,231)   (20,525)
Intangible assets, net 15,393   16,080
Amortization charges associated with finite-lived intangible assets 693 $ 637  
In-process research and development      
Indefinite-lived Intangible Assets [Line Items]      
Indefinite-lived intangible assets: 1,009   1,009
Developed-product-technology rights      
Finite-Lived Intangible Assets [Line Items]      
Gross carrying amounts 29,038   29,028
Accumulated amortization (15,679)   (15,045)
Other intangible assets, net 13,359   13,983
Licensing rights      
Finite-Lived Intangible Assets [Line Items]      
Gross carrying amounts 3,864   3,864
Accumulated amortization (3,160)   (3,123)
Other intangible assets, net 704   741
Marketing-related rights      
Finite-Lived Intangible Assets [Line Items]      
Gross carrying amounts 1,326   1,326
Accumulated amortization (1,188)   (1,167)
Other intangible assets, net 138   159
Research and development technology rights      
Finite-Lived Intangible Assets [Line Items]      
Gross carrying amounts 1,387   1,378
Accumulated amortization (1,204)   (1,190)
Other intangible assets, net $ 183   $ 188