Revenues - Narrative (Details) $ in Millions	3 Months Ended	12 Months Ended
	Dec. 31, 2022 USD ($)	Dec. 31, 2022 USD ($) segment customer	Dec. 31, 2021 USD ($) customer	Dec. 31, 2020 USD ($) customer
Revenue from Contract with Customer [Abstract]
Number of operating segments | segment		1
Revenue from External Customer [Line Items]
Number of major customers (as defined) accounting for more than 10% of total revenue | customer		3	3	3
Major customers (as defined) accounting for more than 10% of gross trade receivables | customer		3	3
Combined trade receivables for all major customers (as defined) as a percentage of net trade receivables	75.00%	75.00%	73.00%
Percentage of worldwide gross revenues derived from major customers (as defined) on a combined basis		82.00%
Total product sales		$ 26,323	$ 25,979	$ 25,424
Percentage of net trade receivables due from customers located outside the United States, primarily in Europe	26.00%	26.00%	27.00%
Total revenues		$ 26,323	$ 25,979	25,424
US
Revenue from External Customer [Line Items]
Total product sales		18,595	18,194	18,496
ROW [Member]
Revenue from External Customer [Line Items]
Total product sales		7,728	7,785	6,928
Product sales
Revenue from External Customer [Line Items]
Total product sales		24,801	24,297	24,240
Total revenues		24,801	24,297	24,240
Product sales | US
Revenue from External Customer [Line Items]
Total product sales		17,743	17,286	17,985
Product sales | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales		7,058	7,011	6,255
Enbrel® (etanercept) [Member]
Revenue from External Customer [Line Items]
Total product sales		4,117	4,465	4,996
Enbrel® (etanercept) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		4,044	4,352	4,855
Enbrel® (etanercept) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		73	113	141
Prolia® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total product sales		3,628	3,248	2,763
Prolia® (denosumab) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		2,465	2,150	1,830
Prolia® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		1,163	1,098	933
Otezla [Member]
Revenue from External Customer [Line Items]
Total product sales		2,288	2,249	2,195
Otezla [Member] | US
Revenue from External Customer [Line Items]
Total revenues		1,886	1,804	1,790
Otezla [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		402	445	405
XGEVA® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total product sales		2,014	2,018	1,899
XGEVA® (denosumab) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		1,480	1,434	1,405
XGEVA® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		534	584	494
Aranesp® (darbepoetin alfa) [Member]
Revenue from External Customer [Line Items]
Total product sales		1,421	1,480	1,568
Aranesp® (darbepoetin alfa) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		521	537	629
Aranesp® (darbepoetin alfa) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		900	943	939
Nplate
Revenue from External Customer [Line Items]
Total product sales		1,307	1,027	850
Nplate | US
Revenue from External Customer [Line Items]
Total revenues		848	566	485
Nplate | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	$ 459		461	365
Repatha (evolocumab) [Member]
Revenue from External Customer [Line Items]
Total product sales		1,296	1,117	887
Repatha (evolocumab) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		608	557	459
Repatha (evolocumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		688	560	428
Kyprolis [Member]
Revenue from External Customer [Line Items]
Total product sales		1,247	1,108	1,065
Kyprolis [Member] | US
Revenue from External Customer [Line Items]
Total revenues		850	736	710
Kyprolis [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		397	372	355
Neulasta® (pegfilgrastim) [Member]
Revenue from External Customer [Line Items]
Total product sales		1,126	1,734	2,293
Neulasta® (pegfilgrastim) [Member] | US
Revenue from External Customer [Line Items]
Total revenues		959	1,514	2,001
Neulasta® (pegfilgrastim) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		167	220	292
Evenity
Revenue from External Customer [Line Items]
Total product sales		787	530	350
Evenity | US
Revenue from External Customer [Line Items]
Total revenues		533	331	191
Evenity | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		254	199	159
Other products [Member]
Revenue from External Customer [Line Items]
Total product sales		5,570	5,321	5,374
Other products [Member] | US
Revenue from External Customer [Line Items]
Total revenues		3,549	3,305	3,630
Other products [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues		2,021	2,016	1,744
Other revenues [Member]
Revenue from External Customer [Line Items]
Total product sales		1,522	1,682	1,184
Total revenues		1,522	1,682	1,184
Other revenues [Member] | US
Revenue from External Customer [Line Items]
Total product sales		852	908	511
Other revenues [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales		670	774	673
AmerisourceBergen Corporation [Member] | Product sales
Revenue from External Customer [Line Items]
Total product sales		15,443	14,783	14,743
McKesson Corporation [Member] | Product sales
Revenue from External Customer [Line Items]
Total product sales		17,305	15,187	13,779
Cardinal Health, Inc. [Member] | Product sales
Revenue from External Customer [Line Items]
Total product sales		$ 8,319	$ 7,681	$ 7,332