Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities:
Net income	$ 4,936	$ 3,994
Depreciation, amortization and other	2,506	2,546
Deferred income taxes	(847)	(264)
Acquired in-process research and development	0	1,505
Income (Loss) from Equity Method Investments	(713)	(130)
Loss on divestiture	565	0
Other items, net	236	57
Changes in operating assets and liabilities, net of acquisitions:
Trade receivables, net	(566)	(269)
Inventories	(651)	(215)
Other assets	166	(373)
Accounts payable	(142)	(260)
Accrued income taxes, net	(492)	(719)
Long-term tax liabilities	185	102
Other liabilities	463	219
Net cash provided by operating activities	7,072	6,453
Cash flows from investing activities:
Purchases of marketable securities	(2,363)	(8,901)
Proceeds from sales of marketable securities	0	4,403
Proceeds from maturities of marketable securities	447	7,927
Purchases of property, plant and equipment	(596)	(593)
Cash paid for acquisitions, net of cash acquired	0	(1,639)
Other	(59)	(234)
Net cash (used in) provided by investing activities	(2,571)	963
Cash flows from financing activities:
Net proceeds from issuance of debt	6,938	4,946
Extinguishment of debt	(297)	0
Repurchases of common stock (Note 10)	(6,360)	(3,532)
Dividends paid	(3,156)	(3,023)
Other	(113)	(104)
Net cash used in financing activities	(2,988)	(1,713)
Increase in cash and cash equivalents	1,513	5,703
Cash and cash equivalents at beginning of period	7,989	6,266
Cash and cash equivalents at end of period	$ 9,502	$ 11,969