The cash outflow associated with the acquisition of a business, net of the cash acquired from the purchase.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 13
-Subparagraph (b)
-URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3213-108585

Name:	us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

Subsequent events (Details) - USD ($) $ / shares in Units, $ in Millions		9 Months Ended
	Oct. 20, 2022	Sep. 30, 2022	Sep. 30, 2021
Subsequent Event [Line Items]
Payments to acquire business		$ 0	$ 1,639
ChemoCentryx, Inc. \| Subsequent Event
Subsequent Event [Line Items]
Business acquisition, share price (in dollars per share)	$ 52.00
Payments to acquire business	$ 3,700