Condensed Consolidated Statements of Income - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenues:
Total revenues	$ 6,652	$ 6,706	$ 19,484	$ 19,133
Operating expenses:
Cost of sales	1,588	1,609	4,659	4,736
Research and development	1,112	1,422	3,110	3,471
Acquired in-process research and development	0	0	0	1,505
Selling, general and administrative	1,287	1,305	3,842	3,943
Other	5	(8)	537	143
Total operating expenses	3,992	4,328	12,148	13,798
Operating income	2,660	2,378	7,336	5,335
Interest expense, net	(368)	(296)	(991)	(862)
Other income (expense), net	100	73	(747)	97
Income before income taxes	2,392	2,155	5,598	4,570
Provision for income taxes	249	271	662	576
Net income	$ 2,143	$ 1,884	$ 4,936	$ 3,994
Earnings per share:
Basic (in usd per share)	$ 4.01	$ 3.32	$ 9.16	$ 6.98
Diluted (in usd per share)	$ 3.98	$ 3.31	$ 9.11	$ 6.93
Shares used in calculation of earnings per share:
Basic (in shares)	535	567	539	572
Diluted (in shares)	538	570	542	576
Product sales
Revenues:
Total revenues	$ 6,237	$ 6,320	$ 18,249	$ 18,026
Other revenues
Revenues:
Total revenues	$ 415	$ 386	$ 1,235	$ 1,107