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Acquisitions - Narrative (Details)
$ in Millions
3 Months Ended 12 Months Ended
Nov. 21, 2019
USD ($)
Jul. 15, 2019
USD ($)
Mar. 31, 2018
USD ($)
Dec. 31, 2020
USD ($)
market
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Business Acquisition [Line Items]            
Goodwill       $ 14,689 $ 14,703 $ 14,699
Estimated blended statutory rate       20.00%    
Kirin-Amgen, Inc. (K-A)            
Business Acquisition [Line Items]            
Percentage of voting interests acquired     50.00%      
Ownership percentage     50.00%      
Otezla            
Business Acquisition [Line Items]            
Approved markets | market       50    
Cash paid $ 13,400          
Adjustments to carrying value of intangible assets 119          
Adjustments to deferred tax liability 24          
Adjustments to deferred credit $ 96          
Otezla | Developed Technology Rights            
Business Acquisition [Line Items]            
Weighted average period of amortization 8 years 6 months          
Nuevolution            
Business Acquisition [Line Items]            
Consideration transferred   $ 183        
Fair value of liabilities assumed, deferred tax liabilities   22        
Fair value of assets acquired and liabilities assumed, net other assets and liabilities   29        
Goodwill   $ 26        
Nuevolution | R & D Technology rights            
Business Acquisition [Line Items]            
Weighted average period of amortization   10 years        
Finite-lived Intangible Assets Acquired   $ 150        
Kirin-Amgen, Inc. (K-A)            
Business Acquisition [Line Items]            
Consideration transferred     $ 657      
Percentage of voting interests acquired     50.00%      
Ownership interest in acquiree prior to acquisition (as a percent)     50.00%      
Net gain on remeasurement     $ 80      
Cash paid     780      
Estimated fair values of contingent consideration obligations     45      
Fair value of assets acquired, cash     977      
Fair value of liabilities assumed, deferred tax liabilities     102      
Fair value of assets acquired and liabilities assumed, net other assets and liabilities     131      
Goodwill     $ 6      
Kirin-Amgen, Inc. (K-A) | Licensing rights            
Business Acquisition [Line Items]            
Weighted average period of amortization     4 years      
Fair value of assets acquired, licensing rights     $ 470      
Assembled Workforce [Member] | Otezla | Marketing-Related Rights            
Business Acquisition [Line Items]            
Weighted average period of amortization 5 years          
Inventories [Member] | Otezla            
Business Acquisition [Line Items]            
Acquired assets, weighted useful life 2 years 6 months