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Goodwill and other intangible assets (Identifiable Intangible Assets) (Details) - USD ($)
$ in Millions
Sep. 30, 2018
Dec. 31, 2017
Finite-Lived Intangible Assets [Line Items]    
Gross carrying amounts $ 18,801 $ 18,344
Accumulated amortization (11,075) (10,121)
Intangible assets, net 7,726 8,223
Gross carrying amount 18,857 18,730
Accumulated amortization (11,075) (10,121)
Intangible assets, net 7,782 8,609
In-process Research and Development [Member]    
Indefinite-lived Intangible Assets [Line Items]    
Indefinite-lived intangible assets 56 386
Developed-Product-Technology Rights [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross carrying amounts 12,586 12,589
Accumulated amortization (7,312) (6,796)
Intangible assets, net 5,274 5,793
Licensing Rights [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross carrying amounts 3,771 3,275
Accumulated amortization (1,921) (1,601)
Intangible assets, net 1,850 1,674
Marketing-Related Rights [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross carrying amounts 1,285 1,319
Accumulated amortization (982) (920)
Intangible assets, net 303 399
R&D Technology Rights [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross carrying amounts 1,159 1,161
Accumulated amortization (860) (804)
Intangible assets, net $ 299 $ 357