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Summary of significant accounting policies (Details)
$ in Millions
9 Months Ended
Sep. 30, 2018
USD ($)
segment
Dec. 31, 2017
USD ($)
Accounting Policies [Abstract]    
Number of operating segments | segment 1  
Accumulated depreciation and amortization on property, plant and equipment $ 8,000 $ 7,600
Change in estimate of sales deductions for prior period sales as a pct of total sales deductions (less than) 1.00%  
Sales return provisions as a percentage of gross product sales (less than) 1.00%  
New Accounting Pronouncement, Early Adoption [Line Items]    
Accumulated deficit $ (15,987) (5,072)
Difference between Revenue Guidance in Effect before and after Topic 606 [Member] | Accounting Standards Update 2014-09 [Member]    
New Accounting Pronouncement, Early Adoption [Line Items]    
Accumulated deficit   $ 25