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Goodwill and intangible assets (Identifiable Intangible Assets) (Details) - USD ($)
$ in Millions
Dec. 31, 2017
Dec. 31, 2016
Finite-lived intangible assets:    
Gross carrying amount $ 18,344 $ 18,264
Accumulated amortization (10,121) (8,744)
Other intangible assets, net 8,223 9,520
Indefinite-lived intangible assets:    
Identifiable intangible assets 18,730 19,023
Accumulated amortization (10,121) (8,744)
Identifiable intangible assets, net 8,609 10,279
IPR&D [Member]    
Indefinite-lived intangible assets:    
Indefinite-lived intangible assets 386 759
Developed product technology rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 12,589 12,534
Accumulated amortization (6,796) (5,947)
Other intangible assets, net 5,793 6,587
Licensing rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 3,275 3,275
Accumulated amortization (1,601) (1,300)
Other intangible assets, net 1,674 1,975
Marketing-related rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 1,319 1,333
Accumulated amortization (920) (793)
Other intangible assets, net 399 540
R&D technology rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 1,161 1,122
Accumulated amortization (804) (704)
Other intangible assets, net $ 357 $ 418