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Quarterly financial data (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]  
Quarterly financial data (unaudited)
Quarterly financial data is summarized as follows (in millions, except per share data):
 
2017 Quarters ended
 
December 31
 
September 30
 
June 30
 
March 31
Product sales
$
5,569

 
$
5,453

 
$
5,574

 
$
5,199

Gross profit from product sales
$
4,510

 
$
4,463

 
$
4,550

 
$
4,203

Net (loss) income
$
(4,264
)
 
$
2,021

 
$
2,151

 
$
2,071

(Loss) earnings per share:
 
 
 
 
 
 
 
Basic
$
(5.89
)
 
$
2.78

 
$
2.93

 
$
2.81

Diluted(1)
$
(5.89
)
 
$
2.76

 
$
2.91

 
$
2.79

 
2016 Quarters ended
 
December 31
 
September 30
 
June 30
 
March 31
Product sales
$
5,663

 
$
5,516

 
$
5,474

 
$
5,239

Gross profit from product sales
$
4,596

 
$
4,489

 
$
4,424

 
$
4,221

Net income
$
1,935

 
$
2,017

 
$
1,870

 
$
1,900

Earnings per share:
 
 
 
 
 
 
 
Basic
$
2.61

 
$
2.70

 
$
2.49

 
$
2.52

Diluted
$
2.59

 
$
2.68

 
$
2.47

 
$
2.50


(1) During periods of net loss, diluted loss per share is equal to basic loss per share as the anti-dilutive effect of potential common shares is disregarded.