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Goodwill and other intangible assets
6 Months Ended
Jun. 30, 2016
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and other intangible assets
Goodwill and other intangible assets
Goodwill
Changes in the carrying amounts of goodwill were as follows (in millions):
 
Six months ended June 30,
 
2016
 
2015
Beginning balance
$
14,787

 
$
14,788

Goodwill related to acquisitions of businesses(1)
2

 

Currency translation adjustments
10

 
(65
)
Ending balance
$
14,799

 
$
14,723

(1) 
Consists of goodwill recognized on the acquisition dates of business combinations and subsequent adjustments to these amounts resulting from changes to the acquisition date fair values of net assets acquired in the business combinations recorded during their respective measurement periods.
Identifiable intangible assets
Identifiable intangible assets consisted of the following (in millions):
 
June 30, 2016
 
December 31, 2015
 
Gross
carrying
amount
 
Accumulated
amortization
 
Intangible
assets, net
 
Gross
carrying
amount
 
Accumulated
amortization
 
Intangible
assets, net
Finite-lived intangible assets:
 
 
 
 
 
 
 
 
 
 
 
Developed product technology rights
$
12,313

 
$
(5,472
)
 
$
6,841

 
$
12,310

 
$
(4,996
)
 
$
7,314

Licensing rights
3,275

 
(1,149
)
 
2,126

 
3,275

 
(998
)
 
2,277

Research and development technology rights
1,138

 
(675
)
 
463

 
1,134

 
(635
)
 
499

Marketing-related rights
1,349

 
(726
)
 
623

 
1,186

 
(650
)
 
536

Total finite-lived intangible assets
18,075

 
(8,022
)
 
10,053

 
17,905

 
(7,279
)
 
10,626

Indefinite-lived intangible assets:
 
 
 
 
 
 
 
 
 
 
 
IPR&D
1,015

 

 
1,015

 
1,015

 

 
1,015

Total identifiable intangible assets
$
19,090

 
$
(8,022
)
 
$
11,068

 
$
18,920

 
$
(7,279
)
 
$
11,641


Developed product technology rights consist of rights related to marketed products acquired in business combinations. Licensing rights consist primarily of contractual rights acquired in business combinations to receive future milestones, royalties and profit sharing payments, capitalized payments to third parties for milestones related to regulatory approvals to commercialize products and up-front payments associated with royalty obligations for marketed products. Research and development (R&D) technology rights consist of technology used in R&D with alternative future uses. Marketing-related intangible assets consist primarily of rights related to the sale and distribution of marketed products.
IPR&D consists of R&D projects acquired in a business combination that are not complete at the time of acquisition due to remaining technological risks and/or lack of receipt of required regulatory approvals. As of June 30, 2016, the projects include primarily AMG 899, acquired in the acquisition of Dezima (see Note 3, Business combinations); oprozomib, acquired in the acquisition of Onyx Pharmaceuticals, Inc. (Onyx); and Parsabiv (etelcalcetide), acquired in the acquisition of KAI Pharmaceuticals.
All IPR&D projects have major risks and uncertainties associated with the timely and successful completion of development and commercialization of these product candidates, including our ability to confirm their safety and efficacy based on data from clinical trials, our ability to obtain necessary regulatory approvals and our ability to successfully complete these tasks within budgeted costs. We are not permitted to market a human therapeutic without obtaining regulatory approvals, and such approvals require our completing clinical trials that demonstrate a product candidate is safe and effective. In addition, the availability and extent of coverage and reimbursement from third-party payers, including government healthcare programs and private insurance plans, as well as competitive product launches, impact the revenues a product can generate. Consequently, the eventual realized value, if any, of these acquired IPR&D projects may vary from their estimated fair values. We review IPR&D projects for impairment annually, whenever events or changes in circumstances indicate that the carrying amount may not be recoverable and upon the establishment of technological feasibility or regulatory approval.
During the three months ended June 30, 2016 and 2015, we recognized amortization charges associated with our finite-lived intangible assets of $371 million and $345 million, respectively. During the six months ended June 30, 2016 and 2015, we recognized amortization charges associated with our finite-lived intangible assets of $740 million and $686 million, respectively. The total estimated amortization charges for our finite-lived intangible assets for the remaining six months ending December 31, 2016, and the years ending December 31, 2017, 2018, 2019, 2020 and 2021, are $0.7 billion, $1.3 billion, $1.2 billion, $1.1 billion, $1.0 billion and $0.9 billion, respectively.