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Summary of significant accounting policies (Details) (USD $)
In Millions, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
segment
Dec. 31, 2013
Dec. 31, 2012
Accounting Policies [Abstract]                      
Number of business segment                 1us-gaap_NumberOfOperatingSegments    
Revenue from External Customer [Line Items]                      
Product sales $ 5,174us-gaap_SalesRevenueGoodsNet $ 4,848us-gaap_SalesRevenueGoodsNet $ 4,949us-gaap_SalesRevenueGoodsNet $ 4,356us-gaap_SalesRevenueGoodsNet $ 4,799us-gaap_SalesRevenueGoodsNet $ 4,647us-gaap_SalesRevenueGoodsNet $ 4,595us-gaap_SalesRevenueGoodsNet $ 4,151us-gaap_SalesRevenueGoodsNet $ 19,327us-gaap_SalesRevenueGoodsNet $ 18,192us-gaap_SalesRevenueGoodsNet $ 16,639us-gaap_SalesRevenueGoodsNet
Restricted investments 0us-gaap_RestrictedInvestmentsNoncurrent       3,412us-gaap_RestrictedInvestmentsNoncurrent       0us-gaap_RestrictedInvestmentsNoncurrent 3,412us-gaap_RestrictedInvestmentsNoncurrent  
NEUPOGEN [Member]                      
Revenue from External Customer [Line Items]                      
Product sales                 1,159us-gaap_SalesRevenueGoodsNet
/ us-gaap_ProductOrServiceAxis
= amgn_NEUPOGENMember
1,398us-gaap_SalesRevenueGoodsNet
/ us-gaap_ProductOrServiceAxis
= amgn_NEUPOGENMember
1,260us-gaap_SalesRevenueGoodsNet
/ us-gaap_ProductOrServiceAxis
= amgn_NEUPOGENMember
NEUPOGEN [Member] | U.S. federal government stockpiles [Member]                      
Revenue from External Customer [Line Items]                      
Product sales                   $ 155us-gaap_SalesRevenueGoodsNet
/ us-gaap_MajorCustomersAxis
= amgn_U.S.FederalGovernmentStockpilesMember
/ us-gaap_ProductOrServiceAxis
= amgn_NEUPOGENMember