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Quarterly financial data (unaudited) (Details) (USD $)
In Millions, except Per Share data, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Quarterly Financial Information Disclosure [Abstract]                      
Product sales $ 5,174us-gaap_SalesRevenueGoodsNet $ 4,848us-gaap_SalesRevenueGoodsNet $ 4,949us-gaap_SalesRevenueGoodsNet $ 4,356us-gaap_SalesRevenueGoodsNet $ 4,799us-gaap_SalesRevenueGoodsNet $ 4,647us-gaap_SalesRevenueGoodsNet $ 4,595us-gaap_SalesRevenueGoodsNet $ 4,151us-gaap_SalesRevenueGoodsNet $ 19,327us-gaap_SalesRevenueGoodsNet $ 18,192us-gaap_SalesRevenueGoodsNet $ 16,639us-gaap_SalesRevenueGoodsNet
Gross profit from product sales 3,991us-gaap_GrossProfit 3,780us-gaap_GrossProfit 3,868us-gaap_GrossProfit 3,266us-gaap_GrossProfit 3,770us-gaap_GrossProfit 3,859us-gaap_GrossProfit 3,810us-gaap_GrossProfit 3,407us-gaap_GrossProfit      
Net income $ 1,294us-gaap_NetIncomeLoss $ 1,244us-gaap_NetIncomeLoss $ 1,547us-gaap_NetIncomeLoss $ 1,073us-gaap_NetIncomeLoss $ 1,021us-gaap_NetIncomeLoss $ 1,368us-gaap_NetIncomeLoss $ 1,258us-gaap_NetIncomeLoss $ 1,434us-gaap_NetIncomeLoss $ 5,158us-gaap_NetIncomeLoss $ 5,081us-gaap_NetIncomeLoss $ 4,345us-gaap_NetIncomeLoss
Earnings per share:                      
Basic (in usd per share) $ 1.70us-gaap_EarningsPerShareBasic $ 1.63us-gaap_EarningsPerShareBasic $ 2.04us-gaap_EarningsPerShareBasic $ 1.42us-gaap_EarningsPerShareBasic $ 1.35us-gaap_EarningsPerShareBasic $ 1.81us-gaap_EarningsPerShareBasic $ 1.67us-gaap_EarningsPerShareBasic $ 1.91us-gaap_EarningsPerShareBasic $ 6.80us-gaap_EarningsPerShareBasic $ 6.75us-gaap_EarningsPerShareBasic $ 5.61us-gaap_EarningsPerShareBasic
Diluted (in usd per share) $ 1.68us-gaap_EarningsPerShareDiluted $ 1.61us-gaap_EarningsPerShareDiluted $ 2.01us-gaap_EarningsPerShareDiluted $ 1.40us-gaap_EarningsPerShareDiluted $ 1.33us-gaap_EarningsPerShareDiluted $ 1.79us-gaap_EarningsPerShareDiluted $ 1.65us-gaap_EarningsPerShareDiluted $ 1.88us-gaap_EarningsPerShareDiluted $ 6.70us-gaap_EarningsPerShareDiluted $ 6.64us-gaap_EarningsPerShareDiluted $ 5.52us-gaap_EarningsPerShareDiluted