Goodwill and other intangible assets (Details Textual) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Finite-Lived Intangible Assets [Line Items]
Amortization charges associated with finite-lived intangible assets	$ 341,000,000	$ 119,000,000	$ 698,000,000	$ 236,000,000
Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract]
Total estimated amortization of finite- lived intangible assets for the six months ended 2014	670,000,000		670,000,000
Total estimated amortization of finite- lived intangible assets for 2015	1,300,000,000		1,300,000,000
Total estimated amortization of finite- lived intangible assets for 2016	1,300,000,000		1,300,000,000
Total estimated amortization of finite- lived intangible assets for 2017	1,200,000,000		1,200,000,000
Total estimated amortization of finite- lived intangible assets for 2018	999,000,000		999,000,000
Total estimated amortization of finite- lived intangible assets for 2019	926,000,000		926,000,000
Glaxo Group Limited [Member]
Finite-Lived Intangible Assets [Line Items]
Amount of payments to be made in exchange for the early termination of the Collaboration Agreement	$ 275,000,000		$ 275,000,000