<ARTICLE>  5
<LEGEND>
This schedule contains summary financial information extracted
from the December 31, 1999, Income Statement and Balance Sheet
and is qualified in its entirety by reference to such
financial statements.


<MULTIPLIER>            1,000

                           
<PERIOD-TYPE>                 12-MOS
<FISCAL-YEAR-END>             DEC-31-1999
<PERIOD-END>                  DEC-31-1999
<CASH>                          310,553
<SECURITIES>                    657,449
<RECEIVABLES>                   626,741
<ALLOWANCES>                          0
<INVENTORY>                     185,796
<CURRENT-ASSETS>              1,786,928
<PP&E>                          576,992
<DEPRECIATION>                  240,806
<TOTAL-ASSETS>                2,354,625
<CURRENT-LIABILITIES>           275,535
<BONDS>                           9,350
<PREFERRED-MANDATORY>                 0
<PREFERRED>                           0
<COMMON>                          4,080
<OTHER-SE>                    2,043,425
<TOTAL-LIABILITY-AND-EQUITY>  2,354,625
<SALES>                       2,322,370
<TOTAL-REVENUES>              2,322,370
<CGS>                           940,083
<TOTAL-COSTS>                   940,083
<OTHER-EXPENSES>                650,449
<LOSS-PROVISION>                      0
<INTEREST-EXPENSE>                  579
<INCOME-PRETAX>                 802,120
<INCOME-TAX>                    252,457
<INCOME-CONTINUING>             549,663
<DISCONTINUED>                        0
<EXTRAORDINARY>                       0
<CHANGES>                             0
<NET-INCOME>                    549,663
<EPS-BASIC>                      1.36
<EPS-DILUTED>                      1.32
<FN>
All information restated for pooling of interest
with SALIX Technologies, Inc.