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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 UenMxYIZn4De1/HtXeesJPv9A4ToDunzEclhWeE+zErexTM2Vf2pWqSR/6EpNOaK
 KdNAR7XmXI7tvadz5iu1TA==

<SEC-DOCUMENT>0000911420-06-000610.txt : 20061019
<SEC-HEADER>0000911420-06-000610.hdr.sgml : 20061019
<ACCEPTANCE-DATETIME>20061019160919
ACCESSION NUMBER:		0000911420-06-000610
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060706
FILED AS OF DATE:		20061019
DATE AS OF CHANGE:		20061019

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ENZO BIOCHEM INC
		CENTRAL INDEX KEY:			0000316253
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		IRS NUMBER:				132866202
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			0731

	BUSINESS ADDRESS:	
		STREET 1:		60 EXECUTIVE BLVD
		CITY:			FARMINGDALE
		STATE:			NY
		ZIP:			11735
		BUSINESS PHONE:		5167555500

	MAIL ADDRESS:	
		STREET 1:		ENZO BIOCHEM INC
		STREET 2:		60 EXECUTIVE BLVD
		CITY:			FARMINGDALE
		STATE:			NY
		ZIP:			11735

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			THALENFELD BARBARA E
		CENTRAL INDEX KEY:			0001236358

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09974
		FILM NUMBER:		061153522

	BUSINESS ADDRESS:	
		STREET 1:		C/O ENZO BIOCHEM INC
		STREET 2:		527 MADISON AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2125830100

	MAIL ADDRESS:	
		STREET 1:		527 MADISON AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>p238178478_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-07-06</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000316253</issuerCik>
        <issuerName>ENZO BIOCHEM INC</issuerName>
        <issuerTradingSymbol>ENZ</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001236358</rptOwnerCik>
            <rptOwnerName>THALENFELD BARBARA E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ENZO BIOCHEM, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>527 MADISON AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP, Corporate Development</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2006-07-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1803</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>74343</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Employee Stock Option</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2006-07-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>6700</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>1996-07-30</value>
            </exerciseDate>
            <expirationDate>
                <value>2006-07-30</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, par value $0.01 per share</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>6700</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>56704</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The Reporting Person exercised a stock option to purchase 6,700 shares of Common Stock and paid the exercise price thereof by
 the surrender of 4,897 shares of Common Stock, for a net gain in outstanding shares of Common Stock of 1,803 shares.</footnote>
        <footnote id="F2">As of the date hereof, the Reporting Person directly beneficially owned 16,620 shares of Common Stock, 1,019 shares of Common
 Stock in Enzo Biochem's 401(K) Plan, and 56,704 options to purchase Common Stock, par value $0.01 per share, which are
 currently exercisable.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Barbara E. Thalenfeld</signatureName>
        <signatureDate>2006-10-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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