0000315066-16-005625.txt : 20160218 0000315066-16-005625.hdr.sgml : 20160218 20160218140038 ACCESSION NUMBER: 0000315066-16-005625 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160217 FILED AS OF DATE: 20160218 DATE AS OF CHANGE: 20160218 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: PROTEOSTASIS THERAPEUTICS, INC. CENTRAL INDEX KEY: 0001445283 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 000000000 STATE OF INCORPORATION: DE BUSINESS ADDRESS: STREET 1: 200 TECHNOLOGY SQUARE CITY: CAMBRIDGE STATE: MA ZIP: 02139 BUSINESS PHONE: 617-225-0096 MAIL ADDRESS: STREET 1: 200 TECHNOLOGY SQUARE CITY: CAMBRIDGE STATE: MA ZIP: 02139 FORMER COMPANY: FORMER CONFORMED NAME: PROTEOSTASIS THERAPEUTICS INC DATE OF NAME CHANGE: 20080916 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: FMR LLC CENTRAL INDEX KEY: 0000315066 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-37695 FILM NUMBER: 161437037 BUSINESS ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 BUSINESS PHONE: 6175706339 MAIL ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 FORMER NAME: FORMER CONFORMED NAME: FMR CORP DATE OF NAME CHANGE: 19920717 4 1 primary_doc.xml PRIMARY DOCUMENT X0306 4 2016-02-17 1 0001445283 PROTEOSTASIS THERAPEUTICS, INC. PTI 0000315066 FMR LLC 245 SUMMER STREET BOSTON MA 02210 0 0 0 1 See Remark 1 Common Stock 2016-02-17 4 C 0 925051 A 1318932 I F-Prime Capital Partners Healthcare Fund II LP Common Stock 2016-02-17 4 C 0 183880 A 1502812 I F-Prime Capital Partners Healthcare Fund II LP Common Stock 2016-02-17 4 P 0 375000 8 A 1877812 I F-Prime Capital Partners Healthcare Fund II LP Series A Convertible Preferred Stock 2016-02-17 4 C 0 10000000 D Common Stock 925051 0 I F-Prime Capital Partners Healthcare Fund II LP Series B Convertible Preferred Stock 2016-02-17 4 C 0 1987782 D Common Stock 183880 0 I F-Prime Capital Partners Healthcare Fund II LP On February 17, 2016, in connection with the completion of the issuer's initial public offering, all shares of Convertible Preferred Stock converted into shares of Common Stock at a 10.8102-for-one conversion ratio. Includes 393,881 shares of Common Stock issued as payment of accrued dividends upon conversion of the Series A Convertible Preferred Stock on February 17, 2016. Remark 1: Abigail P. Johnson is a Director, the Vice Chairman, the Chief Executive Officer and the President of FMR LLC. Members of the Johnson family, including Abigail P. Johnson, are the predominant owners, directly or through trusts, of Series B voting common shares of FMR LLC, representing 49% of the voting power of FMR LLC. The Johnson family group and all other Series B shareholders have entered into a shareholders' voting agreement under which all Series B voting common shares will be voted in accordance with the majority vote of Series B voting common shares. Accordingly, through their ownership of voting common shares and the execution of the shareholders' voting agreement, members of the Johnson family may be deemed, under the Investment Company Act of 1940, to form a controlling group with respect to FMR LLC. The address of Abigail P. Johnson is c/o FMR LLC, 245 Summer Street, Boston, MA 02110. Remark 2: The general partner of F-Prime Capital Partners Healthcare Fund II LP is F-Prime Capital Partners Healthcare Advisors Fund II LP. F-Prime Capital Partners Healthcare Advisors Fund II LP is solely managed by Impresa Management LLC, its general partner and investment manager. Impresa Management LLC is owned, directly or indirectly, by various shareholders and employees of FMR LLC, including certain members of the Johnson family. Exhibit List: Exhibit 24 - Powers of Attorney. Daniel T. Gallagher, Duly authorized under Powers of Attorney, by and on behalf of FMR LLC and its direct and indirect subsidiaries and Abigail P. Johnson 2016-02-18 EX-24 2 exhibit24poa.txt EX-24 DOCUMENT POWER OF ATTORNEY WHEREAS, FMR LLC ("FMR") has appointed Marc R. Bryant, with full power of substitution, as its true and lawful attorney, with full power and authority to execute such documents and to make such regulatory or other filings and amendments thereto (the "Filings") as shall from time to time be required pursuant to the Securities Exchange Act of 1934, as amended, any rules or regulations adopted thereunder, and such other U.S. and non-U.S. laws, rules or regulations as shall from time to time be applicable in respect of the beneficial ownership of securities directly or indirectly attributable to FMR and its direct and indirect subsidiaries, and generally to do all such things in its name and on its behalf in connection therewith as said attorney-in-fact deems necessary or appropriate to cause such filings to be completed and filed. NOW, THEREFORE, the undersigned hereby constitutes and apppoints Daniel T. Gallagher as his substitute, to have all the powers of the undersigned with respect to the Filings, when the undersigned is unavailable. The Power of Attorney shall remain in full force and effect only for such time as the undersigned shall continue to be an officer of Fidelity Management & Research Company, provided that, notwithstanding the foregoing, this Power of Attorney may be revoked at any time by the undersigned in writing. /s/ Marc R. Bryant Marc R. Bryant Dated: November 30, 2015 POWER OF ATTORNEY WHEREAS, Abigail P. Johnson has appointed Scott C. Goebel, with full power of substitution, as her true and lawful attorney, with full power and authority to execute such documents and to make such regulatory or other filings and amendments thereto (the "Filings") as shall from time to time be required pursuant to the Securities Exchange Act of 1934, as amended, any rules or regulations adpoted thereunder, and such other U.S. and non-U.S. laws, rules or regulations as shall from time to time be applicable in respect of the beneficial ownership of securities directly or indirectly attributable to her. NOW, THEREFORE, the undersigned hereby constitutes and appoints Daniel T. Gallagher as his substitute, to have all the powers of the undersigned with respect to the Filings, when the undersigned is unavailable. The Power of Attorney shall remain in full force and effect only for such time as the undersigned shall continue to be an officer of Fidelity Management & Research Company, provided that, notwithstanding the foregoing, this Power of Attorney may be revoked at any time by the undersigned in writing. /s/ Scott C. Goebel Scott C. Goebel Dated: June 18, 2014