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Acquisitions, Divestitures, Research Collaborations and License Agreements - Textual (Detail)
In Millions, unless otherwise specified
12 Months Ended
Dec. 31, 2011
USD ($)
Dec. 31, 2012
Endocyte [Member]
USD ($)
Dec. 31, 2012
AiCuris [Member]
USD ($)
Dec. 31, 2012
AiCuris [Member]
EUR (€)
May 16, 2011
Inspire Pharmaceuticals [Member]
USD ($)
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Upfront payment related to licensing agreement   $ 120 $ 140 € 110  
Potential future milestone payments   880.0   332.5  
Purchase price for acquisition         420
Amount of cash paid per share for acquisition         $ 5.00
Gain on sale of manufacturing facilities and related assets $ 127