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Other (Income) Expense, Net - Narrative (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 28, 2017
Sep. 30, 2015
Jun. 30, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Component of Other Income / Expense of Nonoperating [Line Items]            
Foreign exchange losses related to Venezuela       $ 0 $ 0 $ 876
Loss on extinguishment of debt       191    
Marketable Securities, Realized Gain (Loss)       291    
Litigation settlement $ (80)     0 (625) 0
Net charge related to the settlement of Vioxx shareholder class action litigation       0 0 680
Contribution expense           78
Interest paid       723 686 653
AstraZeneca LP            
Component of Other Income / Expense of Nonoperating [Line Items]            
Other income       $ 232 98 182
CGRP receptor antagonists            
Component of Other Income / Expense of Nonoperating [Line Items]            
Gain (loss) on sale of clinical development programs         100 250
ophthalmic products            
Component of Other Income / Expense of Nonoperating [Line Items]            
Gain on disposition of business           147
Patent litigation            
Component of Other Income / Expense of Nonoperating [Line Items]            
Litigation settlement         $ 117  
Vioxx Securities Lawsuits | Vioxx            
Component of Other Income / Expense of Nonoperating [Line Items]            
Net charge related to the settlement of Vioxx shareholder class action litigation           $ 680
Venezuela            
Component of Other Income / Expense of Nonoperating [Line Items]            
Foreign exchange losses related to Venezuela   $ 138 $ 876