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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Segment Reporting Information [Line Items]        
Sales $ 10,536 $ 10,073 $ 29,692 $ 29,283
corticotropin marketing rights        
Segment Reporting Information [Line Items]        
Proceeds from sale of marketing rights     75  
Operating Segments        
Segment Reporting Information [Line Items]        
Sales 10,420 9,828 29,109 28,500
Operating Segments | Total Pharmaceutical segment sales        
Segment Reporting Information [Line Items]        
Sales 9,443 8,925 26,247 25,755
Operating Segments | Total Pharmaceutical segment sales | Zetia        
Segment Reporting Information [Line Items]        
Sales 671 633 1,985 1,836
Operating Segments | Total Pharmaceutical segment sales | Vytorin        
Segment Reporting Information [Line Items]        
Sales 273 302 843 942
Operating Segments | Total Pharmaceutical segment sales | Januvia        
Segment Reporting Information [Line Items]        
Sales 1,006 1,014 2,976 2,942
Operating Segments | Total Pharmaceutical segment sales | Janumet        
Segment Reporting Information [Line Items]        
Sales 548 562 1,624 1,625
Operating Segments | Total Pharmaceutical segment sales | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 195 190 571 538
Operating Segments | Total Pharmaceutical segment sales | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 148 176 446 437
Operating Segments | Total Pharmaceutical segment sales | Dulera        
Segment Reporting Information [Line Items]        
Sales 97 133 331 383
Operating Segments | Total Pharmaceutical segment sales | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 101 95 268 288
Operating Segments | Total Pharmaceutical segment sales | Zepatier        
Segment Reporting Information [Line Items]        
Sales 164 0 326 0
Operating Segments | Total Pharmaceutical segment sales | Isentress        
Segment Reporting Information [Line Items]        
Sales 372 377 1,050 1,137
Operating Segments | Total Pharmaceutical segment sales | Cubicin        
Segment Reporting Information [Line Items]        
Sales 320 325 969 805
Operating Segments | Total Pharmaceutical segment sales | Noxafil        
Segment Reporting Information [Line Items]        
Sales 147 132 434 360
Operating Segments | Total Pharmaceutical segment sales | Invanz        
Segment Reporting Information [Line Items]        
Sales 152 153 409 424
Operating Segments | Total Pharmaceutical segment sales | Cancidas        
Segment Reporting Information [Line Items]        
Sales 142 139 406 436
Operating Segments | Total Pharmaceutical segment sales | Bridion        
Segment Reporting Information [Line Items]        
Sales 139 89 343 262
Operating Segments | Total Pharmaceutical segment sales | Primaxin        
Segment Reporting Information [Line Items]        
Sales 77 75 231 228
Operating Segments | Total Pharmaceutical segment sales | Remicade        
Segment Reporting Information [Line Items]        
Sales 311 442 999 1,398
Operating Segments | Total Pharmaceutical segment sales | Simponi        
Segment Reporting Information [Line Items]        
Sales 193 178 581 505
Operating Segments | Total Pharmaceutical segment sales | Keytruda        
Segment Reporting Information [Line Items]        
Sales 356 159 919 352
Operating Segments | Total Pharmaceutical segment sales | Emend        
Segment Reporting Information [Line Items]        
Sales 137 141 405 396
Operating Segments | Total Pharmaceutical segment sales | Temodar        
Segment Reporting Information [Line Items]        
Sales 78 83 216 238
Operating Segments | Total Pharmaceutical segment sales | Singulair        
Segment Reporting Information [Line Items]        
Sales 239 201 705 658
Operating Segments | Total Pharmaceutical segment sales | Nasonex        
Segment Reporting Information [Line Items]        
Sales 94 121 425 625
Operating Segments | Total Pharmaceutical segment sales | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 131 150 389 524
Operating Segments | Total Pharmaceutical segment sales | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 114 123 342 361
Operating Segments | Total Pharmaceutical segment sales | Fosamax        
Segment Reporting Information [Line Items]        
Sales 68 86 217 277
Operating Segments | Total Pharmaceutical segment sales | Zocor        
Segment Reporting Information [Line Items]        
Sales 54 56 150 168
Operating Segments | Total Pharmaceutical segment sales | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 860 625 1,631 1,410
Operating Segments | Total Pharmaceutical segment sales | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 496 390 1,236 1,096
Operating Segments | Total Pharmaceutical segment sales | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 171 160 489 441
Operating Segments | Total Pharmaceutical segment sales | Zostavax        
Segment Reporting Information [Line Items]        
Sales 190 179 464 503
Operating Segments | Total Pharmaceutical segment sales | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 175 138 403 354
Operating Segments | Total Pharmaceutical segment sales | Other Pharmaceutical        
Segment Reporting Information [Line Items]        
Sales 1,224 1,298 3,464 3,806
Operating Segments | Other segment sales        
Segment Reporting Information [Line Items]        
Sales 977 903 2,862 2,745
Other        
Segment Reporting Information [Line Items]        
Sales $ 116 $ 245 $ 583 $ 783