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Share-Based Compensation - Schedule of Share-Based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 20,736 $ 18,609 $ 14,029
Cost of Goods Sold      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense 362 645 775
Selling, General and Administrative Expense      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense 17,395 15,130 10,567
Research and Development Expense      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 2,979 $ 2,834 $ 2,687