Exhibit 99.1

COMERICA REPORTS SECOND QUARTER NET INCOME OF $70 MILLION

Broad-Based Improvement in Credit Quality Continued,

With Positive Trends in Leading Indicators

Net Interest Margin Expanded 10 Basis Points

Strong Capital and Liquidity to Support Future Growth

DALLAS/July 21, 2010 — Comerica Incorporated (NYSE: CMA) today reported second quarter 2010 net income from continuing operations of $70 million, compared to $35 million for the first quarter 2010. Second quarter net income attributable to common shares of $69 million, compared to a net loss attributable to common shares of $71 million for the first quarter 2010, reflected a lower provision for loan losses resulting from continued improvement in credit quality and the benefit of the first quarter 2010 full redemption of $2.25 billion of preferred stock issued to the U.S. Treasury. Second quarter 2010 included a $126 million provision for loan losses, compared to $175 million for the first quarter 2010.

(dollar amounts in millions, except per share data)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income	$	422		$	415		$	402
Provision for loan losses	126			175			312
Noninterest income	194			194			298
Noninterest expenses	397			404			429
Income from continuing operations, net of tax	70			35			18
Income from discontinued operations, net of tax	—			17			—
Net income	70			52			18
Preferred stock dividends to U.S. Treasury	—			123		(a)	34
Income allocated to participating securities	1			—			—
Net income (loss) attributable to common shares	69			(71		)	(16		)
Diluted income (loss) per common share	0.39			(0.46		)	(0.11		)
Tier 1 capital ratio	10.61		% (b)	10.38		%	11.58		%
Tangible common equity ratio (c)	10.11			9.68			7.55
Net interest margin	3.28			3.18			2.73

(a) First quarter 2010 included non-cash charges of $99 million.

(b) June 30, 2010 ratio is estimated.

(c) See Reconciliation of Non-GAAP Financial Measures.

“Our financial results reflect the many positive trends we have seen over several quarters,” said Ralph W. Babb Jr., chairman and chief executive officer. “This includes three consecutive quarters of broad-based improvement in credit quality, with leading indicators of future credit quality also pointing positive. Our net interest margin continued to expand, and our expenses remained well controlled.  We have strong capital and liquidity to support future growth, with the flexibility to grow organically as well as by acquisition.

- more -

“We continue to reach out to our customers, taking their pulse on the economy, their current financial needs and future plans.  As a relationship-focused ‘Main Street’ bank, this type of proactive outreach is how we differentiate ourselves. Since the onset of the economic downturn, we stepped-up our calling efforts to be sure we were ideally positioned to assist customers in navigating the economic environment and to meet their needs as the economy improves.  This is reflected in our loan pipeline, which is now at its highest level in more than two years.

“While the pace of the economic recovery remains uncertain, we continue to focus on growing new relationships, and expanding existing ones, with confidence we are in the right markets with the right people and a full array of products and services to make a positive difference for our customers, shareholders and the communities we serve.”

Second Quarter 2010 Highlights Compared to First Quarter 2010

·Net interest income increased $7 million to $422 million for the second quarter 2010, compared to $415 million for the first quarter 2010. The net interest margin of 3.28 percent increased 10 basis points, from 3.18 percent in the first quarter 2010, with little change from the impact of excess liquidity, represented by average balances deposited with the Federal Reserve Bank.

·Net credit-related charge-offs decreased $27 million to $146 million, or 1.44 percent of average total loans, for the second quarter 2010, compared to $173 million, or 1.68 percent of average total loans, for the first quarter 2010.

·Watch list loans - generally consistent with regulatory defined special mention, substandard and doubtful (nonaccrual) loans - declined $851 million to $6.7 billion from March 31, 2010 to June 30, 2010.

·The provision for credit losses decreased $56 million to $126 million for the second quarter 2010, compared to $182 million for the first quarter 2010, due to continued broad-based improvement in credit metrics.

·The tangible common equity ratio was 10.11 percent at June 30, 2010, an increase of 43 basis points from March 31, 2010. The estimated Tier 1 common ratio was 9.79 percent and the estimated Tier 1 capital ratio was 10.61 percent at June 30, 2010, increases of 22 basis points and 23 basis points, respectively, from March 31, 2010.

·There were no preferred stock dividends in second quarter 2010, compared to $123 million in the first quarter 2010. Comerica fully redeemed the $2.25 billion of preferred stock issued to the U.S. Treasury under the Capital Purchase Program in March 2010.

2

Net Interest Income and Net Interest Margin

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income	$	422		$	415		$	402
Net interest margin	3.28		%	3.18		%	2.73		%
Selected average balances:
Total earning assets	$	51,835		$	52,941		$	59,522
Total investment securities	7,262			7,382			9,786
Federal Reserve Bank deposits (excess liquidity) (a)	3,719			4,092			1,833
Total loans	40,672			41,313			47,648
Total core deposits (b)	38,928			37,236			34,925
Total noninterest-bearing deposits	15,218			14,624			12,546

(a) See Reconciliation of Non-GAAP Financial Measures.

(b) Core deposits exclude other time deposits and foreign office time deposits.

·The $7 million increase in net interest income in the second quarter 2010, when compared to first quarter 2010, resulted primarily from an increase in the net interest margin.

·The net interest margin of 3.28 percent increased 10 basis points, compared to first quarter 2010, primarily from maturing higher-cost wholesale funding and a less costly blend of core deposits. The net interest margin was reduced by approximately 23 and 24 basis points in the second and first quarters of 2010, respectively, from excess liquidity, which was represented by $3.7 billion of average balances deposited with the Federal Reserve Bank in the second quarter 2010, compared to $4.1 billion of average balances in the first quarter 2010. At June 30, 2010, excess liquidity was represented by $3.3 billion of balances deposited with the Federal Reserve Bank, compared to $3.8 billion at March 31, 2010.

·Average earning assets decreased $1.1 billion, reflecting decreases of $641 million in average loans and $465 million in other earning assets. Over one-half of the decrease in average loans was in the Commercial Real Estate business line, while Mortgage Banker Finance, National Dealer Services, Technology and Life Sciences and Private Banking showed increases. The pace of decline in loans in the second quarter 2010 continued to slow when compared to declines of $1.4 billion in the first quarter 2010 and $2.0 billion in the fourth quarter 2009. While customers remained cautious, credit line utilization was stable since the middle of the first quarter 2010.

·Second quarter 2010 average core deposits increased $1.7 billion compared to first quarter 2010, including a $1.3 billion increase in money market and NOW deposits and a $594 million increase in noninterest-bearing deposits.

Noninterest Income

Noninterest income was $194 million for both the second and first quarters of 2010.  Commercial service charges declined from a seasonally high first quarter 2010, while card fees and letter of credit fees increased in the second quarter 2010, compared to the first quarter 2010.

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Noninterest Expenses

Noninterest expenses were $397 million for the second quarter 2010, compared to $404 million for the first quarter 2010. The $7 million decrease in noninterest expenses in the second quarter 2010, compared to the first quarter 2010, was primarily due to decreases in the provision for credit losses on lending-related commitments ($7 million) and other real estate expense ($7 million), partially offset by an increase in salaries expense ($10 million).  Salaries expense reflected the impact of one additional day in the second quarter, annual merit increases and increased share-based compensation expense. Full-time equivalent staff decreased by approximately 100 employees from March 31, 2010 and approximately 400 employees, or four percent, from June 30, 2009.

Credit Quality

“The continued broad-based improvement in credit quality reflects our early recognition of issues, and our ability to quickly and proactively work through problem loans,” Babb said.  “Overall charge-offs declined in the second quarter, with a notable decrease in commercial real estate charge-offs. The pace of improvement in credit quality is significant and faster than we had expected. A key indicator of future credit quality is our watch list loans, which are down $851 million.  As a result of the positive trends we have seen, we have reduced our charge-off outlook for full-year 2010.”

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·Net credit-related charge-offs decreased $27 million to $146 million in the second quarter 2010, from $173 million in the first quarter 2010. The decrease in net credit-related charge-offs resulted primarily from a $50 million decrease in the Commercial Real Estate business line in the second quarter 2010, with decreases in all markets, partially offset by a $32 million increase in the Middle Market business line, primarily in Other Markets.

·Nonperforming assets decreased $37 million to $1.2 billion, or 2.98 percent of total loans and foreclosed property, at June 30, 2010.

·Watch list loans declined $851 million to $6.7 billion from March 31, 2010 to June 30, 2010.

·The provision for credit losses decreased $56 million, with significant declines in the Midwest, Western and Texas markets, partially offset by increases in Florida and Other Markets.

·During the second quarter 2010, $199 million of loan relationships greater than $2 million were transferred to nonaccrual status, a decrease of $46 million from the first quarter 2010.  Of the transfers of loan relationships greater than $2 million to nonaccrual in the second quarter 2010, $118 million were in Middle Market, primarily Midwest and Other Markets, $33 million were in the Commercial Real Estate business line and $30 million were in Private Banking.

·Nonaccrual loans were charged down 45 percent and 44 percent as of June 30, 2010 and March 31, 2010, respectively, compared to 39 percent one year ago.

·Foreclosed property increased $4 million to $93 million at June 30, 2010, from $89 million at March 31, 2010.

·Loans past due 90 days or more and still accruing were $115 million at June 30, 2010, an increase of $32 million compared to March 31, 2010.

·The allowance for loan losses to total loans ratio was 2.38 percent at June 30, 2010, compared to 2.42 percent at March 31, 2010.

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net credit-related charge-offs	$	146		$	173		$	248
Net credit-related charge-offs/Average total loans	1.44		%	1.68		%	2.08		%
Provision for loan losses	$	126		$	175		$	312
Provision for credit losses on lending-related commitments	—			7			(4		)
Total provision for credit losses	126			182			308
Nonperforming loans	1,121			1,162			1,130
Nonperforming assets (NPAs)	1,214			1,251			1,230
NPAs/Total loans and foreclosed property	2.98		%	3.06		%	2.64		%
Loans past due 90 days or more and still accruing	$	115		$	83		$	210
Allowance for loan losses	967			987			880
Allowance for credit losses on lending-related commitments (a)	44			44			33
Total allowance for credit losses	1,011			1,031			913
Allowance for loan losses/Total loans	2.38		%	2.42		%	1.89		%
Allowance for loan losses/Nonperforming loans	86			85			78

(a) Included in “Accrued expenses and other liabilities” on the consolidated balance sheets.

5

Balance Sheet and Capital Management

Total assets and common shareholders’ equity were $55.9 billion and $5.8 billion, respectively, at June 30, 2010, compared to $57.1 billion and $5.7 billion, respectively, at March 31, 2010. There were approximately 176 million common shares outstanding at June 30, 2010.

In the second quarter 2010, the U.S. Treasury sold 11.5 million warrants to purchase an equal amount of shares of Comerica common stock at $29.40 per share, for $16.00 per warrant.  The warrants were originally issued to the U.S. Treasury in connection with Comerica’s participation in the Capital Purchase Program.  Comerica fully redeemed the $2.25 billion of related preferred stock in March 2010. The sale of the warrants by the U.S. Treasury had no impact on Comerica’s equity and the warrants remained outstanding at June 30, 2010.

Comerica’s tangible common equity ratio was 10.11 percent at June 30, 2010, an increase of 43 basis points from March 31, 2010. The estimated Tier 1 common ratio was 9.79 percent and the estimated Tier 1 capital ratio was 10.61 percent at June 30, 2010, increases of 22 basis points and 23 basis points, respectively, from March 31, 2010.

Full-Year 2010 Outlook

For full-year 2010, management expects the following, based on an uncertain pace of economic recovery.

·Management expects loans to be stable from period-end June 30, 2010 to period-end December 31, 2010.  Investment securities, excluding auction-rate securities, are expected to remain at a level similar to June 30, 2010.

·Based on excess liquidity remaining similar to June 30, 2010 through year-end 2010, management expects an average net interest margin between 3.20 percent and 3.30 percent for full-year 2010, reflecting the benefit, compared to 2009, from improved loan pricing and lower funding costs.  No Federal Funds rate increase is assumed.

·Management expects net credit-related charge-offs between $600 million and $650 million for full-year 2010. The provision for credit losses is expected to be below net credit-related charge-offs.

·Management expects a low to mid single-digit decline in noninterest income compared to 2009, after excluding $243 million of 2009 net securities gains.  Included in the outlook is an estimated $5 million negative impact on service charge income in the second half of 2010 from overdraft policy changes consistent with new regulations issued by the Federal Reserve.

·Management expects a low single-digit decrease in noninterest expenses compared to 2009.

·Management expects income tax expense to approximate 35 percent of income before income taxes less approximately $60 million of permanent differences related to low-income housing and bank-owned life insurance, partially offset by approximately $5 million of state adjustments.

6

Business Segments

Comerica’s continuing operations are strategically aligned into three major business segments: the Business Bank, the Retail Bank, and Wealth & Institutional Management.  The Finance Division also is included as a segment. The financial results below are based on the internal business unit structure of the Corporation and methodologies in effect at June 30, 2010 and are presented on a fully taxable equivalent (FTE) basis. The accompanying narrative addresses second quarter 2010 results compared to first quarter 2010.

The following table presents net income (loss) by business segment.

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Business Bank	$	135		$	89		$	5
Retail Bank	(3		)	(7		)	(18		)
Wealth & Institutional Management	5			11			15
	137			93			2
Finance	(57		)	(59		)	8
Other (a)	(10		)	18			8
Total	$	70		$	52		$	18

(a) Includes discontinued operations and items not directly associated with the three major business segments or the Finance Division.

Business Bank

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	351		$	341		$	328
Provision for loan losses	83			137			252
Noninterest income	78			76			50
Noninterest expenses	157			162			157
Net income	135			89			5
Net credit-related charge-offs	113			137			211
Selected average balances:
Assets	30,609			31,293			37,521
Loans	30,353			30,918			36,760
Deposits	19,069			17,750			14,827
Net interest margin	4.63		%	4.48		%	3.58		%

·Average loans decreased $565 million, reflecting declines in all major markets. Over one-half of the decline was in Commercial Real Estate, while Mortgage Banker Finance, National Dealer Services and Technology and Life Sciences showed increases. The decline in loans continued to slow in the second quarter 2010.

·Average deposits increased $1.3 billion, primarily due to increases in the Financial Services Division and Global Corporate Banking.

·The net interest margin of 4.63 percent increased 15 basis points, primarily due to the benefit provided by the increases in noninterest-bearing deposits and money market deposits.

·The provision for loan losses decreased $54 million, primarily due to decreases in Commercial Real Estate and Middle Market.

·Noninterest expenses decreased $5 million, primarily due to decreases in the provision for credit losses on lending-related commitments and other real estate expense, partially offset by increases in salaries expense and allocated corporate overhead expenses.

7

Retail Bank

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	134		$	130		$	128
Provision for loan losses	20			31			42
Noninterest income	42			44			46
Noninterest expenses	160			154			167
Net loss	(3		)	(7		)	(18		)
Net credit-related charge-offs	22			26			29
Selected average balances:
Assets	5,937			6,106			6,693
Loans	5,446			5,599			6,115
Deposits	16,930			16,718			17,666
Net interest margin	3.17		%	3.18		%	2.90		%

·Average loans decreased $153 million, reflecting declines across all markets and business lines.

·Average deposits increased $212 million, due to increases in all deposit categories except customer certificates of deposit.

·The provision for loan losses decreased $11 million, primarily due to a decrease in Personal Banking.

·Noninterest expenses increased $6 million, primarily due to increases in salaries expense and allocated corporate overhead expenses.

Wealth and Institutional Management

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	45		$	42		$	40
Provision for loan losses	19			12			13
Noninterest income	61			60			73
Noninterest expenses	79			73			77
Net income	5			11			15
Net credit-related charge-offs	11			10			8
Selected average balances:
Assets	4,903			4,862			4,965
Loans	4,840			4,789			4,776
Deposits	2,924			2,791			2,599
Net interest margin	3.73		%	3.53		%	3.29		%

·Average loans increased $51 million.

·Average deposits increased $133 million, reflecting increases in money market and noninterest-bearing deposits.

·The net interest margin of 3.73 percent increased 20 basis points, primarily due to an increase in loan spreads.

·The provision for loan losses increased $7 million due to an increase in the Florida market.

·Noninterest expenses increased $6 million, due to increases in salaries expense and nominal increases in other expense categories.

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Geographic Market Segments

Comerica also provides market segment results for four primary geographic markets: Midwest, Western, Texas and Florida.  In addition to the four primary geographic markets, Other Markets and International are also reported as market segments.  The financial results below are based on methodologies in effect at June 30, 2010 and are presented on a fully taxable equivalent (FTE) basis. The accompanying narrative addresses second quarter 2010 results compared to first quarter 2010.

The following table presents net income (loss) by market segment.

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Midwest	$	57		$	26		$	—
Western	39			22			(7		)
Texas	26			14			5
Florida	(9		)	1			(8		)
Other Markets	8			16			6
International	16			14			6
	137			93			2
Finance & Other Businesses (a)	(67		)	(41		)	16
Total	$	70		$	52		$	18

(a) Includes discontinued operations and items not directly associated with the geographic markets.

Midwest Market

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	211		$	205		$	200
Provision for loan losses	40			81			119
Noninterest income	97			102			92
Noninterest expenses	181			186			186
Net income	57			26			—
Net credit-related charge-offs	51			55			99
Selected average balances:
Assets	14,990			15,573			18,122
Loans	14,959			15,332			17,427
Deposits	18,005			17,068			17,166
Net interest margin	4.69		%	4.86		%	4.56		%

·Average loans decreased $373 million, primarily reflecting declines in Global Corporate Banking and Middle Market. The decline in loans continued to slow in the second quarter 2010.

·Average deposits increased $937 million, primarily due to increases in the Financial Services Division, Global Corporate Banking and Small Business Banking.

·The net interest margin of 4.69 percent decreased 17 basis points, due to an increase in deposits, a decrease in deposit spreads and a decline in loans.

·The provision for loan losses decreased $41 million, primarily due to a decrease in Middle Market.

·Noninterest expenses decreased $5 million, due to a decrease in the provision for credit losses on lending-related commitments, partially offset by an increase in allocated corporate overhead expense.

9

Western Market

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	164		$	161		$	154
Provision for loan losses	27			59			90
Noninterest income	33			36			32
Noninterest expenses	110			105			113
Net income (loss)	39			22			(7		)
Net credit-related charge-offs	47			64			70
Selected average balances:
Assets	13,006			13,175			14,901
Loans	12,792			12,980			14,684
Deposits	11,951			11,927			10,717
Net interest margin	5.13		%	5.04		%	4.20		%

·Average loans decreased $188 million, primarily due to a decline in Commercial Real Estate. The decline in loans continued to slow in the second quarter 2010.

·Average deposits increased $24 million, primarily due to increases in Technology and Life Sciences, the Financial Services Division and Private Banking, partially offset by decreases in Commercial Real Estate and Middle Market.

·The net interest margin of 5.13 percent increased nine basis points, primarily due to an increase in loan spreads.

·The provision for loan losses decreased $32 million, primarily due to decreases in Commercial Real Estate and Middle Market.

·Noninterest expenses increased $5 million, primarily due to increases in salaries expense and allocated corporate overhead expense.

Texas Market

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	81		$	79		$	73
Provision for loan losses	(1		)	17			28
Noninterest income	23			20			21
Noninterest expenses	65			60			60
Net income	26			14			5
Total net credit-related charge-offs	8			25			11
Selected average balances:
Assets	6,652			6,892			7,798
Loans	6,428			6,704			7,547
Deposits	5,316			4,957			4,496
Net interest margin	5.05		%	4.79		%	3.88		%

·Average loans decreased $276 million, primarily due to decreases in Energy Lending, Middle Market and Commercial Real Estate.

·Average deposits increased $359 million, primarily due to increases in Global Corporate Banking and Energy Lending.

·The net interest margin of 5.05 percent increased 26 basis points, primarily due to the benefit provided by an increase in noninterest-bearing and NOW deposits.

·The provision for loan losses decreased $18 million, primarily due to a decline Commercial Real Estate.

·Noninterest expenses increased $5 million due to increases in salaries expense and allocated corporate overhead expenses.

10

Florida Market

(dollar amounts in millions)	2nd Qtr ‘10			1st Qtr ‘10			2nd Qtr ‘09
Net interest income (FTE)	$	12		$	10		$	11
Provision for loan losses	17			3			20
Noninterest income	4			3			3
Noninterest expenses	12			9			9
Net income (loss)	(9		)	1			(8		)
Net credit-related charge-offs	7			10			23
Selected average balances:
Assets	1,576			1,576			1,820
Loans	1,575			1,576			1,820
Deposits	404			361			331
Net interest margin	2.94		%	2.54		%	2.44		%

·Average deposits increased $43 million, primarily due to an increase in Global Corporate Banking.

·The net interest margin of 2.94 percent increased 40 basis points primarily due to an increase in loan spreads and the benefit provided by an increase in noninterest-bearing deposits.

·The provision for loan losses increased $14 million primarily due to Private Banking.

Conference Call and Webcast

Comerica will host a conference call to review second quarter 2010 financial results at 7 a.m. CT Wednesday, July 21, 2010. Interested parties may access the conference call by calling (800) 309-2262 or (706) 679-5261 (event ID No. 82678684). The call and supplemental financial information can also be accessed on the Internet at www.comerica.com.  A replay will be available approximately two hours following the conference call through July 30, 2010. The conference call replay can be accessed by calling (800) 642-1687 or (706) 645-9291 (event ID No. 82678684). A replay of the Webcast can also be accessed via Comerica’s “Investor Relations” page at www.comerica.com.

Comerica Incorporated is a financial services company headquartered in Dallas, Texas, and strategically aligned by three major business segments: the Business Bank, the Retail Bank, and Wealth & Institutional Management. Comerica focuses on relationships and helping people and businesses be successful. In addition to Texas, Comerica Bank locations can be found in Arizona, California, Florida and Michigan, with select businesses operating in several other states, as well as in Canada and Mexico.

This press release contains both financial measures based on accounting principles generally accepted in the United States (GAAP) and non-GAAP based financial measures, which are used where management believes it to be helpful in understanding Comerica’s results of operations or financial position.  Where non-GAAP financial measures are used, the comparable GAAP financial measure, as well as the reconcilement to the comparable GAAP financial measure, can be found in this press release.  These disclosures should not be viewed as a substitute for operating results determined in accordance with GAAP, nor are they necessarily comparable to non-GAAP performance measures that may be presented by other companies.

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Forward-looking Statements

Any statements in this news release that are not historical facts are forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. Words such as “anticipates,” “believes,” “feels,” “expects,” “estimates,” “seeks,” “strives,” “plans,” “intends,” “outlook,” “forecast,” “position,” “target,” “mission,” “assume,” “achievable,” “potential,” “strategy,” “goal,” “aspiration,” “outcome,” “continue,” “remain,” “maintain,” “trend,” “objective” and variations of such words and similar expressions, or future or conditional verbs such as “will,” “would,” “should,” “could,” “might,” “can,” “may” or similar expressions, as they relate to Comerica or its management, are intended to identify forward-looking statements. These forward-looking statements are predicated on the beliefs and assumptions of Comerica’s management based on information known to Comerica’s management as of the date of this news release and do not purport to speak as of any other date. Forward-looking statements may include descriptions of plans and objectives of Comerica’s management for future or past operations, products or services, and forecasts of Comerica’s revenue, earnings or other measures of economic performance, including statements of profitability, business segments and subsidiaries, estimates of credit trends and global stability. Such statements reflect the view of Comerica’s management as of this date with respect to future events and are subject to risks and uncertainties. Should one or more of these risks materialize or should underlying beliefs or assumptions prove incorrect, Comerica’s actual results could differ materially from those discussed.  Factors that could cause or contribute to such differences are further economic downturns, changes in the pace of an economic recovery and related changes in employment levels, changes in real estate values, fuel prices, energy costs or other events that could affect customer income levels or general economic conditions, the effects of recently enacted legislation, actions taken by or proposed by the U.S. Department of Treasury, the Board of Governors of the Federal Reserve System, the Texas Department of Banking and the Federal Deposit Insurance Corporation, legislation enacted in the future, and the impact and expiration of such legislation and regulatory actions, the effects of war and other armed conflicts or acts of terrorism, the effects of natural disasters including, but not limited to, hurricanes, tornadoes, earthquakes, fires, droughts and floods, the disruption of private or public utilities, the implementation of Comerica’s strategies and business models, management’s ability to maintain and expand customer relationships, changes in customer borrowing, repayment, investment and deposit practices, management’s ability to retain key officers and employees, changes in the accounting treatment of any particular item, the impact of regulatory examinations, declines or other changes in the businesses or industries in which Comerica has a concentration of loans, including, but not limited to, the automotive production industry and the real estate business lines, the anticipated performance of any new banking centers, the entry of new competitors in Comerica’s markets, changes in the level of fee income, changes in applicable laws and regulations, including those concerning taxes, banking, securities and insurance, changes in trade, monetary and fiscal policies, including the interest rate policies of the Board of Governors of the Federal Reserve System, fluctuations in inflation or interest rates, changes in general economic, political or industry conditions and related credit and market conditions, the interdependence of financial service companies and adverse conditions in the stock market. Comerica cautions that the foregoing list of factors is not exclusive. For discussion of factors that may cause actual results to differ from expectations, please refer to our filings with the Securities and Exchange Commission. In particular, please refer to “Item 1A. Risk Factors” beginning on page 11 of Comerica’s Annual Report on Form 10-K for the year ended December 31, 2009 and “Item 1A. Risk Factors” beginning on page 67 of Comerica’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2010. Forward-looking statements speak only as of the date they are made. Comerica does not undertake to update forward-looking statements to reflect facts, circumstances, assumptions or events that occur after the date the forward-looking statements are made. For any forward-looking statements made in this news release or in any documents, Comerica claims the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995.

Media Contact:	Investor Contacts:
Wayne J. Mielke	Darlene P. Persons
(214) 462-4463	(214) 462-6831
	Tracy Fralick
	(214) 462-6834

12

CONSOLIDATED FINANCIAL HIGHLIGHTS (unaudited)

Comerica Incorporated and Subsidiaries

	Three Months Ended									Six Months Ended
	June 30,			March 31,			June 30,			June 30,
(in millions, except per share data)	2010			2010			2009			2010			2009
PER COMMON SHARE AND COMMON STOCK DATA
Diluted net income (loss)	$	0.39		$	(0.46	)	$	(0.11	)	$	(0.01	)	$	(0.27	)
Cash dividends declared	0.05			0.05			0.05			0.10			0.10
Common shareholders’ equity (at period end)	32.85			32.15			32.78
Average diluted shares (in thousands)	178,432			155,155			149,410			165,100			149,334
KEY RATIOS
Return on average common shareholders’ equity	4.89		%	(5.61		)%	(1.25		)%	(0.05		)%	(1.58		)%
Return on average assets	0.50			0.36			0.11			0.43			0.08
Tier 1 common capital ratio (a) (b)	9.79			9.57			7.66
Tier 1 risk-based capital ratio (b)	10.61			10.38			11.58
Total risk-based capital ratio (b)	15.00			14.91			15.97
Leverage ratio (b)	11.35			11.00			12.11
Tangible common equity ratio (a)	10.11			9.68			7.55
AVERAGE BALANCES
Commercial loans	$	20,910		$	21,015		$	25,657		$	20,961		$	26,413
Real estate construction loans	2,987			3,386			4,325			3,185			4,417
Commercial mortgage loans	10,372			10,387			10,476			10,380			10,454
Residential mortgage loans	1,607			1,632			1,795			1,620			1,821
Consumer loans	2,448			2,481			2,572			2,464			2,573
Lease financing	1,108			1,130			1,227			1,119			1,263
International loans	1,240			1,282			1,596			1,261			1,655
Total loans	40,672			41,313			47,648			40,990			48,596
Earning assets	51,835			52,941			59,522			52,385			60,631
Total assets	56,258			57,519			64,256			56,885			65,490
Noninterest-bearing deposits	15,218			14,624			12,546			14,923			11,958
Interest-bearing core deposits	23,710			22,612			22,379			23,165			22,423
Total core deposits	38,928			37,236			34,925			38,088			34,381
Common shareholders’ equity	5,708			5,070			5,016			5,391			5,020
Total shareholders’ equity	5,708			6,864			7,153			6,283			7,154
NET INTEREST INCOME
Net interest income (fully taxable equivalent basis)	$	424		$	416		$	404		$	840		$	790
Fully taxable equivalent adjustment	2			1			2			3			4
Net interest margin	3.28		%	3.18		%	2.73		%	3.23		%	2.63		%
CREDIT QUALITY
Nonaccrual loans	$	1,098		$	1,145		$	1,130
Reduced-rate loans	23			17			—
Total nonperforming loans	1,121			1,162			1,130
Foreclosed property	93			89			100
Total nonperforming assets	1,214			1,251			1,230
Loans past due 90 days or more and still accruing	115			83			210
Gross loan charge-offs	158			184			257			$	342		$	418
Loan recoveries	12			11			9			23			13
Net loan charge-offs	146			173			248			319			405
Lending-related commitment charge-offs	—			—			—			—			—
Total net credit-related charge-offs	146			173			248			319			405
Allowance for loan losses	967			987			880
Allowance for credit losses on lending-related commitments	44			44			33
Total allowance for credit losses	1,011			1,031			913
Allowance for loan losses as a percentage of total loans	2.38		%	2.42		%	1.89		%
Net loan charge-offs as a percentage of average total loans	1.44			1.68			2.08			1.56		%	1.67		%
Net credit-related charge-offs as a percentage of average total loans	1.44			1.68			2.08			1.56			1.67
Nonperforming assets as a percentage of total loans and foreclosed property	2.98			3.06			2.64
Allowance for loan losses as a percentage of total nonperforming loans	86			85			78

(a) See Reconciliation of Non-GAAP Financial Measures.

(b) June 30, 2010 ratios are estimated.

13

CONSOLIDATED BALANCE SHEETS

Comerica Incorporated and Subsidiaries

	June 30,			March 31,			December 31,			June 30,
(in millions, except share data)	2010			2010			2009			2009
	(unaudited)			(unaudited)						(unaudited)
ASSETS
Cash and due from banks	$	816		$	769		$	774		$	948
Federal funds sold and securities purchased under agreements to resell	—			—			—			650
Interest-bearing deposits with banks	3,409			3,860			4,843			3,542
Other short-term investments	134			165			138			129
Investment securities available-for-sale	7,188			7,346			7,416			7,757
Commercial loans	21,151			20,756			21,690			24,922
Real estate construction loans	2,774			3,202			3,461			4,152
Commercial mortgage loans	10,318			10,358			10,457			10,400
Residential mortgage loans	1,606			1,631			1,651			1,759
Consumer loans	2,443			2,472			2,511			2,562
Lease financing	1,084			1,120			1,139			1,234
International loans	1,226			1,306			1,252			1,523
Total loans	40,602			40,845			42,161			46,552
Less allowance for loan losses	(967		)	(987		)	(985		)	(880		)
Net loans	39,635			39,858			41,176			45,672
Premises and equipment	634			637			644			667
Customers’ liability on acceptances outstanding	24			21			11			7
Accrued income and other assets	4,045			4,450			4,247			4,258
Total assets	$	55,885		$	57,106		$	59,249		$	63,630
LIABILITIES AND SHAREHOLDERS’ EQUITY
Noninterest-bearing deposits	$	15,769		$	15,290		$	15,871		$	13,558
Money market and NOW deposits	16,062			16,009			14,450			12,352
Savings deposits	1,407			1,462			1,342			1,348
Customer certificates of deposit	5,893			5,979			6,413			8,524
Other time deposits	165			814			1,047			4,593
Foreign office time deposits	484			412			542			616
Total interest-bearing deposits	24,011			24,676			23,794			27,433
Total deposits	39,780			39,966			39,665			40,991
Short-term borrowings	200			489			462			490
Acceptances outstanding	24			21			11			7
Accrued expenses and other liabilities	1,048			1,047			1,022			1,478
Medium- and long-term debt	9,041			9,915			11,060			13,571
Total liabilities	50,093			51,438			52,220			56,537
Fixed rate cumulative perpetual preferred stock, series F, no par value, $1,000 liquidation value per share:
Authorized - 2,250,000 shares at 12/31/09 and 6/30/09
Issued - 2,250,000 shares at 12/31/09 and 6/30/09	—			—			2,151			2,140
Common stock - $5 par value:
Authorized - 325,000,000 shares
Issued - 203,878,110 shares at 6/30/10 and 3/31/10, 178,735,252 shares at 12/31/09 and 6/30/09	1,019			1,019			894			894
Capital surplus	1,467			1,468			740			731
Accumulated other comprehensive loss	(240		)	(303		)	(336		)	(342		)
Retained earnings	5,124			5,064			5,161			5,257
Less cost of common stock in treasury - 27,561,412 shares at 6/30/10, 27,575,283 shares at 3/31/10, 27,555,623 shares at 12/31/09 and 27,620,471 shares at 6/30/09	(1,578		)	(1,580		)	(1,581		)	(1,587		)
Total shareholders’ equity	5,792			5,668			7,029			7,093
Total liabilities and shareholders’ equity	$	55,885		$	57,106		$	59,249		$	63,630

14

CONSOLIDATED STATEMENTS OF INCOME (unaudited)

Comerica Incorporated and Subsidiaries

	Three Months Ended June 30,					Six Months Ended June 30,
(in millions, except per share data)	2010		2009			2010			2009
INTEREST INCOME
Interest and fees on loans	$	412	$	447		$	824		$	899
Interest on investment securities	61		103			122			212
Interest on short-term investments	3		2			6			4
Total interest income	476		552			952			1,115
INTEREST EXPENSE
Interest on deposits	29		106			64			231
Interest on short-term borrowings	—		—			—			2
Interest on medium- and long-term debt	25		44			51			96
Total interest expense	54		150			115			329
Net interest income	422		402			837			786
Provision for loan losses	126		312			301			515
Net interest income after provision for loan losses	296		90			536			271
NONINTEREST INCOME
Service charges on deposit accounts	52		55			108			113
Fiduciary income	38		41			77			83
Commercial lending fees	22		19			44			37
Letter of credit fees	19		16			37			32
Card fees	15		12			28			24
Foreign exchange income	10		11			20			20
Bank-owned life insurance	9		10			17			18
Brokerage fees	6		8			12			17
Net securities gains	1		113			3			126
Other noninterest income	22		13			42			51
Total noninterest income	194		298			388			521
NONINTEREST EXPENSES
Salaries	179		171			348			342
Employee benefits	45		53			89			108
Total salaries and employee benefits	224		224			437			450
Net occupancy expense	40		38			81			79
Equipment expense	15		15			32			31
Outside processing fee expense	23		25			46			50
Software expense	22		20			44			40
FDIC insurance expense	16		45			33			60
Legal fees	9		10			18			17
Other real estate expense	5		9			17			16
Litigation and operational losses	2		2			3			4
Provision for credit losses on lending-related commitments	—		(4		)	7			(5		)
Other noninterest expenses	41		45			83			84
Total noninterest expenses	397		429			801			826
Income (loss) from continuing operations before income taxes	93		(41		)	123			(34		)
Provision (benefit) for income taxes	23		(59		)	18			(60		)
Income from continuing operations	70		18			105			26
Income from discontinued operations, net of tax	—		—			17			1
NET INCOME	70		18			122			27
Less:
Preferred stock dividends	—		34			123			67
Income allocated to participating securities	1		—			—			—
Net income (loss) attributable to common shares	$	69	$	(16	)	$	(1	)	$	(40	)
Basic earnings per common share:
Income (loss) from continuing operations	$	0.40	$	(0.11	)	$	(0.11	)	$	(0.28	)
Net income (loss)	0.40		(0.11		)	(0.01		)	(0.27		)
Diluted earnings per common share:
Income (loss) from continuing operations	0.39		(0.11		)	(0.11		)	(0.28		)
Net income (loss)	0.39		(0.11		)	(0.01		)	(0.27		)
Cash dividends declared on common stock	9		8			18			15
Cash dividends declared per common share	0.05		0.05			0.10			0.10

15

CONSOLIDATED QUARTERLY STATEMENTS OF INCOME (unaudited)

Comerica Incorporated and Subsidiaries

	Second		First			Fourth			Third			Second			Second Quarter 2010 Compared To:
	Quarter		Quarter			Quarter			Quarter			Quarter			First Quarter 2010					Second Quarter 2009
(in millions, except per share data)	2010		2010			2009			2009			2009			Amount			Percent		Amount			Percent
INTEREST INCOME
Interest and fees on loans	$	412	$	412		$	424		$	444		$	447		$	—		—	%	$	(35	)	(8	)%
Interest on investment securities	61		61			53			64			103			—			(1	)	(42		)	(41	)
Interest on short-term investments	3		3			2			3			2			—			(6	)	1			36
Total interest income	476		476			479			511			552			—			—		(76		)	(14	)
INTEREST EXPENSE
Interest on deposits	29		35			52			89			106			(6		)	(19	)	(77		)	(73	)
Interest on short-term borrowings	—		—			—			—			—			—			N/M		—			(67	)
Interest on medium- and long-term debt	25		26			31			37			44			(1		)	(3	)	(19		)	(44	)
Total interest expense	54		61			83			126			150			(7		)	(12	)	(96		)	(64	)
Net interest income	422		415			396			385			402			7			2		20			5
Provision for loan losses	126		175			256			311			312			(49		)	(27	)	(186		)	(59	)
Net interest income after provision for loan losses	296		240			140			74			90			56			23		206			N/M
NONINTEREST INCOME
Service charges on deposit accounts	52		56			56			59			55			(4		)	(6	)	(3		)	(6	)
Fiduciary income	38		39			38			40			41			(1		)	(1	)	(3		)	(6	)
Commercial lending fees	22		22			21			21			19			—			2		3			19
Letter of credit fees	19		18			19			18			16			1			1		3			13
Card fees	15		13			14			13			12			2			11		3			18
Foreign exchange income	10		10			11			10			11			—			3		(1		)	(5	)
Bank-owned life insurance	9		8			9			8			10			1			—		(1		)	(10	)
Brokerage fees	6		6			7			7			8			—			8		(2		)	(26	)
Net securities gains	1		2			10			107			113			(1		)	(37	)	(112		)	(99	)
Other noninterest income	22		20			29			32			13			2			11		9			67
Total noninterest income	194		194			214			315			298			—			—		(104		)	(35	)
NONINTEREST EXPENSES
Salaries	179		169			174			171			171			10			6		8			5
Employee benefits	45		44			51			51			53			1			2		(8		)	(15	)
Total salaries and employee benefits	224		213			225			222			224			11			5		—			—
Net occupancy expense	40		41			43			40			38			(1		)	(7	)	2			2
Equipment expense	15		17			16			15			15			(2		)	(7	)	—			—
Outside processing fee expense	23		23			23			24			25			—			2		(2		)	(8	)
Software expense	22		22			23			21			20			—			(2	)	2			5
FDIC insurance expense	16		17			15			15			45			(1		)	(1	)	(29		)	(63	)
Legal fees	9		9			12			8			10			—			—		(1		)	(8	)
Other real estate expense	5		12			22			10			9			(7		)	(57	)	(4		)	(48	)
Litigation and operational losses	2		1			3			3			2			1			23		—			(37	)
Provision for credit losses on lending-related commitments	—		7			3			2			(4		)	(7		)	(98	)	4			N/M
Other noninterest expenses	41		42			40			39			45			(1		)	(2	)	(4		)	(4	)
Total noninterest expenses	397		404			425			399			429			(7		)	(2	)	(32		)	(7	)
Income (loss) from continuing operations before income taxes	93		30			(71		)	(10		)	(41		)	63			N/M		134			N/M
Provision (benefit) for income taxes	23		(5		)	(42		)	(29		)	(59		)	28			N/M		82			N/M
Income (loss) from continuing operations	70		35			(29		)	19			18			35			N/M		52			N/M
Income from discontinued operations, net of tax	—		17			—			—			—			(17		)	N/M		—			N/M
NET INCOME (LOSS)	70		52			(29		)	19			18			18			34		52			N/M
Less:
Preferred stock dividends	—		123			33			34			34			(123		)	N/M		(34		)	N/M
Income allocated to participating securities	1		—			—			1			—			1			N/M		1			N/M
Net income (loss) attributable to common shares	$	69	$	(71	)	$	(62	)	$	(16	)	$	(16	)	$	140		N/M	%	$	85		N/M	%
Basic earnings per common share:
Income (loss) from continuing operations	$	0.40	$	(0.57	)	$	(0.42	)	$	(0.10	)	$	(0.11	)	$	0.97		N/M	%	$	0.51		N/M	%
Net income (loss)	0.40		(0.46		)	(0.42		)	(0.10		)	(0.11		)	0.86			N/M		0.51			N/M
Diluted earnings per common share:
Income (loss) from continuing operations	0.39		(0.57		)	(0.42		)	(0.10		)	(0.11		)	0.96			N/M		0.50			N/M
Net income (loss)	0.39		(0.46		)	(0.42		)	(0.10		)	(0.11		)	0.85			N/M		0.50			N/M
Cash dividends declared on common stock	9		9			8			7			8			—			(2	)	1			15
Cash dividends declared per common share	0.05		0.05			0.05			0.05			0.05			—			—		—			—

N/M - Not meaningful

16

ANALYSIS OF THE ALLOWANCE FOR LOAN LOSSES (unaudited)

Comerica Incorporated and Subsidiaries

	2010						2009
(in millions)	2nd Qtr			1st Qtr			4th Qtr			3rd Qtr			2nd Qtr
Balance at beginning of period	$	987		$	985		$	953		$	880		$	816
Loan charge-offs:
Commercial	65			49			113			113			88
Real estate construction:
Commercial Real Estate business line (a)	30			71			33			63			81
Other business lines (b)	—			3			—			1			—
Total real estate construction	30			74			33			64			81
Commercial mortgage:
Commercial Real Estate business line (a)	12			16			27			24			23
Other business lines (b)	36			28			25			15			23
Total commercial mortgage	48			44			52			39			46
Residential mortgage	5			2			6			11			2
Consumer	9			8			9			7			12
Lease financing	1			—			6			6			24
International	—			7			13			5			4
Total loan charge-offs	158			184			232			245			257
Recoveries on loans previously charged-off:
Commercial	4			7			7			3			5
Real estate construction	6			1			—			1			—
Commercial mortgage	1			3			1			—			2
Residential mortgage	—			—			—			—			—
Consumer	1			—			—			1			—
Lease financing	—			—			—			—			1
International	—			—			—			1			1
Total recoveries	12			11			8			6			9
Net loan charge-offs	146			173			224			239			248
Provision for loan losses	126			175			256			311			312
Foreign currency translation adjustment	—			—			—			1			—
Balance at end of period	$	967		$	987		$	985		$	953		$	880
Allowance for loan losses as a percentage of total loans	2.38		%	2.42		%	2.34		%	2.19		%	1.89		%
Net loan charge-offs as a percentage of average total loans	1.44			1.68			2.09			2.14			2.08
Net credit-related charge-offs as a percentage of average total loans	1.44			1.68			2.10			2.14			2.08

(a) Primarily charge-offs of loans to real estate investors and developers.

(b) Primarily charge-offs of loans secured by owner-occupied real estate.

ANALYSIS OF THE ALLOWANCE FOR CREDIT LOSSES ON LENDING-RELATED COMMITMENTS (unaudited)

Comerica Incorporated and Subsidiaries

	2010				2009
(in millions)	2nd Qtr		1st Qtr		4th Qtr		3rd Qtr		2nd Qtr
Balance at beginning of period	$	44	$	37	$	35	$	33	$	37
Less: Charge-offs on lending-related commitments (a)	—		—		1		—		—
Add: Provision for credit losses on lending-related commitments	—		7		3		2		(4		)
Balance at end of period	$	44	$	44	$	37	$	35	$	33
Unfunded lending-related commitments sold	$	2	$	—	$	3	$	1	$	—

(a) Charge-offs result from the sale of unfunded lending-related commitments.

17

NONPERFORMING ASSETS (unaudited)

Comerica Incorporated and Subsidiaries

	2010						2009
(in millions)	2nd Qtr			1st Qtr			4th Qtr			3rd Qtr			2nd Qtr
SUMMARY OF NONPERFORMING ASSETS AND PAST DUE LOANS
Nonaccrual loans:
Commercial	$	239		$	209		$	238		$	290		$	327
Real estate construction:
Commercial Real Estate business line (a)	385			516			507			542			472
Other business lines (b)	4			3			4			4			4
Total real estate construction	389			519			511			546			476
Commercial mortgage:
Commercial Real Estate business line (a)	135			105			127			137			134
Other business lines (b)	257			226			192			161			175
Total commercial mortgage	392			331			319			298			309
Residential mortgage	53			58			50			27			7
Consumer	11			13			12			8			7
Lease financing	11			11			13			18			—
International	3			4			22			7			4
Total nonaccrual loans	1,098			1,145			1,165			1,194			1,130
Reduced-rate loans	23			17			16			2			—
Total nonperforming loans	1,121			1,162			1,181			1,196			1,130
Foreclosed property	93			89			111			109			100
Total nonperforming assets	$	1,214		$	1,251		$	1,292		$	1,305		$	1,230
Nonperforming loans as a percentage of total loans	2.76		%	2.85		%	2.80		%	2.74		%	2.43		%
Nonperforming assets as a percentage of total loans and foreclosed property	2.98			3.06			3.06			2.99			2.64
Allowance for loan losses as a percentage of total nonperforming loans	86			85			83			80			78
Loans past due 90 days or more and still accruing	$	115		$	83		$	101		$	161		$	210
ANALYSIS OF NONACCRUAL LOANS
Nonaccrual loans at beginning of period	$	1,145		$	1,165		$	1,194		$	1,130		$	982
Loans transferred to nonaccrual (c)	199			245			266			361			419
Nonaccrual business loan gross charge-offs (d)	(143		)	(174		)	(217		)	(226		)	(242		)
Loans transferred to accrual status (c)	—			—			—			(4		)	—
Nonaccrual business loans sold (e)	(47		)	(44		)	(10		)	(41		)	(10		)
Payments/Other (f)	(56		)	(47		)	(68		)	(26		)	(19		)
Nonaccrual loans at end of period	$	1,098		$	1,145		$	1,165		$	1,194		$	1,130

(a) Primarily loans to real estate investors and developers.

(b) Primarily loans secured by owner-occupied real estate.

(c) Based on an analysis of nonaccrual loans with book balances greater than $2 million.

(d) Analysis of gross loan charge-offs:

Nonaccrual business loans	$	143	$	174	$	217	$	226	$	242
Performing watch list loans	1		—		—		1		1
Consumer and residential mortgage loans	14		10		15		18		14
Total gross loan charge-offs	$	158	$	184	$	232	$	245	$	257

(e) Analysis of loans sold:

Nonaccrual business loans	$	47	$	44	$	10	$	41	$	10
Performing watch list loans	15		12		1		24		6
Total loans sold	$	62	$	56	$	11	$	65	$	16

(f)Includes net changes related to nonaccrual loans with balances less than $2 million, payments on nonaccrual loans with book balances greater than $2 million and transfers of nonaccrual loans to foreclosed property. Excludes business loan gross charge-offs and business nonaccrual loans sold.

18

ANALYSIS OF NET INTEREST INCOME (FTE) (unaudited)

Comerica Incorporated and Subsidiaries

	Six Months Ended
	June 30, 2010							June 30, 2009
	Average					Average		Average					Average
(dollar amounts in millions)	Balance			Interest		Rate		Balance			Interest		Rate
Commercial loans	$	20,961		$	411	3.95	%	$	26,413		$	453	3.47	%
Real estate construction loans	3,185			48		3.03		4,417			65		2.97
Commercial mortgage loans	10,380			216		4.19		10,454			217		4.19
Residential mortgage loans	1,620			44		5.43		1,821			52		5.70
Consumer loans	2,464			44		3.57		2,573			48		3.72
Lease financing	1,119			21		3.73		1,263			17		2.66
International loans	1,261			25		4.00		1,655			32		3.88
Business loan swap income	—			17		—		—			17		—
Total loans	40,990			826		4.06		48,596			901		3.74
Auction-rate securities available-for-sale	847			5		1.06		1,098			9		1.60
Other investment securities available-for-sale	6,475			118		3.72		8,858			205		4.76
Total investment securities available-for-sale	7,322			123		3.40		9,956			214		4.40
Federal funds sold and securities purchased under agreements to resell	1			—		1.17		35			—		0.32
Interest-bearing deposits with banks (a)	3,944			5		0.25		1,862			2		0.26
Other short-term investments	128			1		1.70		182			2		1.78
Total earning assets	52,385			955		3.67		60,631			1,119		3.73
Cash and due from banks	792							915
Allowance for loan losses	(1,048		)					(872		)
Accrued income and other assets	4,756							4,816
Total assets	$	56,885						$	65,490
Money market and NOW deposits	$	15,709		25		0.32		$	12,319		34		0.56
Savings deposits	1,407			—		0.07		1,316			1		0.14
Customer certificates of deposit	6,049			30		0.97		8,788			113		2.60
Total interest-bearing core deposits	23,165			55		0.48		22,423			148		1.33
Other time deposits	584			9		3.18		5,699			82		2.89
Foreign office time deposits	453			—		0.22		702			1		0.33
Total interest-bearing deposits	24,202			64		0.54		28,824			231		1.62
Short-term borrowings	241			—		0.19		1,682			2		0.26
Medium- and long-term debt	10,169			51		0.99		14,461			96		1.33
Total interest-bearing sources	34,612			115		0.67		44,967			329		1.48
Noninterest-bearing deposits	14,923							11,958
Accrued expenses and other liabilities	1,067							1,411
Total shareholders’ equity	6,283							7,154
Total liabilities and shareholders’ equity	$	56,885						$	65,490
Net interest income/rate spread (FTE)				$	840	3.00					$	790	2.25
FTE adjustment				$	3						$	4
Impact of net noninterest-bearing sources of funds						0.23							0.38
Net interest margin (as a percentage of average earning assets) (FTE) (a)						3.23	%						2.63	%

(a)   Excess liquidity, represented by average balances deposited with the Federal Reserve Bank, reduced the net interest margin by 24 basis points and 7 basis points year-to-date in 2010 and 2009, respectively.  Excluding excess liquidity, the net interest margin would have been 3.47% in 2010 and 2.70% in 2009.  See Reconciliation of Non-GAAP Financial Measures.

19

ANALYSIS OF NET INTEREST INCOME (FTE) (unaudited)

Comerica Incorporated and Subsidiaries

	Three Months Ended
	June 30, 2010							March 31, 2010							June 30, 2009
	Average					Average		Average					Average		Average					Average
(dollar amounts in millions)	Balance			Interest		Rate		Balance			Interest		Rate		Balance			Interest		Rate
Commercial loans	$	20,910		$	206	3.95	%	$	21,015		$	205	3.96	%	$	25,657		$	225	3.55	%
Real estate construction loans	2,987			23		3.13		3,386			25		2.95		4,325			32		2.95
Commercial mortgage loans	10,372			109		4.20		10,387			107		4.18		10,476			108		4.17
Residential mortgage loans	1,607			22		5.44		1,632			22		5.41		1,795			26		5.74
Consumer loans	2,448			22		3.56		2,481			22		3.58		2,572			24		3.65
Lease financing	1,108			10		3.72		1,130			11		3.75		1,227			8		2.48
International loans	1,240			13		4.07		1,282			12		3.93		1,596			16		3.90
Business loan swap income	—			9		—		—			8		—		—			9		—
Total loans	40,672			414		4.07		41,313			412		4.04		47,648			448		3.77
Auction-rate securities available-for-sale	816			3		1.19		879			2		0.93		1,052			4		1.48
Other investment securities available-for-sale	6,446			58		3.71		6,503			60		3.72		8,734			100		4.70
Total investment securities available-for-sale	7,262			61		3.41		7,382			62		3.38		9,786			104		4.35
Federal funds sold and securities purchased under agreements to resell	1			—		1.35		—			—		—		13			—		0.33
Interest-bearing deposits with banks (a)	3,768			3		0.25		4,122			2		0.25		1,876			1		0.28
Other short-term investments	132			—		1.65		124			1		1.75		199			1		1.88
Total earning assets	51,835			478		3.70		52,941			477		3.65		59,522			554		3.75
Cash and due from banks	795							788							881
Allowance for loan losses	(1,037		)					(1,058		)					(913		)
Accrued income and other assets	4,665							4,848							4,766
Total assets	$	56,258						$	57,519						$	64,256
Money market and NOW deposits	$	16,354		13		0.32		$	15,055		12		0.32		$	12,304		15		0.49
Savings deposits	1,429			—		0.07		1,384			—		0.07		1,354			—		0.11
Customer certificates of deposit	5,927			15		0.92		6,173			15		1.02		8,721			55		2.53
Total interest-bearing core deposits	23,710			28		0.45		22,612			27		0.50		22,379			70		1.26
Other time deposits	295			1		2.14		877			8		3.53		5,124			36		2.75
Foreign office time deposits	448			—		0.23		458			—		0.21		734			—		0.26
Total interest-bearing deposits	24,453			29		0.47		23,947			35		0.60		28,237			106		1.50
Short-term borrowings	248			—		0.27		234			—		0.11		1,010			—		0.20
Medium- and long-term debt	9,571			25		1.04		10,775			26		0.95		14,002			44		1.27
Total interest-bearing sources	34,272			54		0.63		34,956			61		0.71		43,249			150		1.40
Noninterest-bearing deposits	15,218							14,624							12,546
Accrued expenses and other liabilities	1,060							1,075							1,308
Total shareholders’ equity	5,708							6,864							7,153
Total liabilities and shareholders’ equity	$	56,258						$	57,519						$	64,256
Net interest income/rate spread (FTE)				$	424	3.07					$	416	2.94					$	404	2.35
FTE adjustment				$	2						$	1						$	2
Impact of net noninterest-bearing sources of funds						0.21							0.24							0.38
Net interest margin (as a percentage of average earning assets) (FTE) (a)						3.28	%						3.18	%						2.73	%

(a) Excess liquidity, represented by average balances deposited with the Federal Reserve Bank, reduced the net interest margin by 23 basis points and 24 basis points in the second and first quarters of 2010, respectively, and by 8 basis points in the second quarter of 2009.  Excluding excess liquidity, the net interest margin would have been 3.51%, 3.42% and 2.81% in each respective period.  See Reconciliation of Non-GAAP Financial Measures.

20

CONSOLIDATED STATISTICAL DATA (unaudited)

Comerica Incorporated and Subsidiaries

	June 30,			March 31,			December 31,			September 30,			June 30,
(in millions, except per share data)	2010			2010			2009			2009			2009
Commercial loans:
Floor plan	$	1,586		$	1,351		$	1,367		$	857		$	1,492
Other	19,565			19,405			20,323			21,689			23,430
Total commercial loans	21,151			20,756			21,690			22,546			24,922
Real estate construction loans:
Commercial Real Estate business line (a)	2,345			2,741			2,988			3,328			3,500
Other business lines (b)	429			461			473			542			652
Total real estate construction loans	2,774			3,202			3,461			3,870			4,152
Commercial mortgage loans:
Commercial Real Estate business line (a)	1,971			1,880			1,824			1,678			1,728
Other business lines (b)	8,347			8,478			8,633			8,702			8,672
Total commercial mortgage loans	10,318			10,358			10,457			10,380			10,400
Residential mortgage loans	1,606			1,631			1,651			1,679			1,759
Consumer loans:
Home equity	1,761			1,782			1,817			1,818			1,814
Other consumer	682			690			694			726			748
Total consumer loans	2,443			2,472			2,511			2,544			2,562
Lease financing	1,084			1,120			1,139			1,197			1,234
International loans	1,226			1,306			1,252			1,355			1,523
Total loans	$	40,602		$	40,845		$	42,161		$	43,571		$	46,552
Goodwill	$	150		$	150		$	150		$	150		$	150
Loan servicing rights	6			6			7			8			9
Tier 1 common capital ratio (c) (d)	9.79		%	9.57		%	8.18		%	8.04		%	7.66		%
Tier 1 risk-based capital ratio (d)	10.61			10.38			12.46			12.21			11.58
Total risk-based capital ratio (d)	15.00			14.91			16.93			16.79			15.97
Leverage ratio (d)	11.35			11.00			13.25			12.46			12.11
Tangible common equity ratio (c)	10.11			9.68			7.99			7.96			7.55
Book value per common share	$	32.85		$	32.15		$	32.27		$	32.36		$	32.78
Market value per share for the quarter:
High	45.85			39.36			32.30			31.83			26.47
Low	35.44			29.68			26.49			19.94			16.03
Close	36.83			38.04			29.57			29.67			21.15
Quarterly ratios:
Return on average common shareholders’ equity	4.89		%	(5.61		)%	(5.10		)%	(1.27		)%	(1.25		)%
Return on average assets	0.50			0.36			(0.19		)	0.12			0.11
Efficiency ratio	64.47			66.45			70.68			67.14			72.75
Number of banking centers	437			449			447			444			441
Number of employees - full time equivalent	9,107			9,215			9,330			9,384			9,497

(a) Primarily loans to real estate investors and developers.

(b) Primarily loans secured by owner-occupied real estate.

(c) See Reconciliation of Non-GAAP Financial Measures.

(d) June 30, 2010 ratios are estimated.

21

PARENT COMPANY ONLY BALANCE SHEETS (unaudited)

Comerica Incorporated

	June 30,			December 31,			June 30,
(in millions, except share data)	2010			2009			2009
ASSETS
Cash and due from subsidiary bank	$	15		$	5		$	5
Short-term investments with subsidiary bank	659			2,150			2,223
Other short-term investments	83			86			80
Investment in subsidiaries, principally banks	5,961			5,710			5,700
Premises and equipment	4			4			4
Other assets	190			186			190
Total assets	$	6,912		$	8,141		$	8,202
LIABILITIES AND SHAREHOLDERS’ EQUITY
Medium- and long-term debt	$	999		$	986		$	985
Other liabilities	121			126			124
Total liabilities	1,120			1,112			1,109
Fixed rate cumulative perpetual preferred stock, series F, no par value, $1,000 liquidation preference per share:
Authorized - 2,250,000 shares at 12/31/09 and 6/30/09
Issued — 2,250,000 shares at 12/31/09 and 6/30/09	—			2,151			2,140
Common stock - $5 par value:
Authorized - 325,000,000 shares
Issued - 203,878,110 shares at 6/30/10 and 178,735,252 shares at 12/31/09 and 6/30/09	1,019			894			894
Capital surplus	1,467			740			731
Accumulated other comprehensive loss	(240		)	(336		)	(342		)
Retained earnings	5,124			5,161			5,257
Less cost of common stock in treasury - 27,561,412 shares at 6/30/10, 27,555,623 shares at 12/31/09 and 27,620,471 shares at 6/30/09	(1,578		)	(1,581		)	(1,587		)
Total shareholders’ equity	5,792			7,029			7,093
Total liabilities and shareholders’ equity	$	6,912		$	8,141		$	8,202

CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS’ EQUITY (unaudited)

Comerica Incorporated and Subsidiaries

											Accumulated
				Common Stock							Other									Total
	Preferred			Shares				Capital			Comprehensive			Retained			Treasury			Shareholders’
(in millions, except per share data)	Stock			Outstanding		Amount		Surplus			Loss			Earnings			Stock			Equity
BALANCE AT DECEMBER 31, 2008	$	2,129		150.5		$	894	$	722		$	(309	)	$	5,345		$	(1,629	)	$	7,152
Net income	—			—		—		—			—			27			—			27
Other comprehensive loss, net of tax	—			—		—		—			(33		)	—			—			(33		)
Total comprehensive loss																				(6		)
Cash dividends declared on preferred stock	—			—		—		—			—			(57		)	—			(57		)
Cash dividends declared on common stock ($0.10 per share)	—			—		—		—			—			(15		)	—			(15		)
Purchase of common stock	—			(0.1	)	—		—			—			—			(1		)	(1		)
Accretion of discount on preferred stock	11			—		—		—			—			(11		)	—			—
Net issuance of common stock under employee stock plans	—			0.7		—		(14		)	—			(32		)	43			(3		)
Share-based compensation	—			—		—		18			—			—			—			18
Other	—			—		—		5			—			—			—			5
BALANCE AT JUNE 30, 2009	$	2,140		151.1		$	894	$	731		$	(342	)	$	5,257		$	(1,587	)	$	7,093
BALANCE AT DECEMBER 31, 2009	$	2,151		151.2		$	894	$	740		$	(336	)	$	5,161		$	(1,581	)	$	7,029
Net income	—			—		—		—			—			122			—			122
Other comprehensive income, net of tax	—			—		—		—			96			—			—			96
Total comprehensive income																				218
Cash dividends declared on preferred stock	—			—		—		—			—			(38		)	—			(38		)
Cash dividends declared on common stock ($0.10 per share)	—			—		—		—			—			(18		)	—			(18		)
Purchase of common stock	—			—		—		—			—			—			(4		)	(4		)
Issuance of common stock	—			25.1		125		724			—			—			—			849
Redemption of preferred stock	(2,250		)	—		—		—			—			—			—			(2,250		)
Redemption discount accretion on preferred stock	94			—		—		—			—			(94		)	—			—
Accretion of discount on preferred stock	5			—		—		—			—			(5		)	—			—
Net issuance of common stock under employee stock plans	—			—		—		(5		)	—			(4		)	6			(3		)
Share-based compensation	—			—		—		11			—			—			—			11
Other	—			—		—		(3		)	—			—			1			(2		)
BALANCE AT JUNE 30, 2010	$	—		176.3		$	1,019	$	1,467		$	(240	)	$	5,124		$	(1,578	)	$	5,792

22

BUSINESS SEGMENT FINANCIAL RESULTS (unaudited)

Comerica Incorporated and Subsidiaries

							Wealth &
(dollar amounts in millions)	Business			Retail			Institutional
Three Months Ended June 30, 2010	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	351		$	134		$	45		$	(103	)	$	(3	)	$	424
Provision for loan losses	83			20			19			—			4			126
Noninterest income	78			42			61			13			—			194
Noninterest expenses	157			160			79			2			(1		)	397
Provision (benefit) for income taxes (FTE)	54			(1		)	3			(35		)	4			25
Income from discontinued operations, net of tax	—			—			—			—			—			—
Net income (loss)	$	135		$	(3	)	$	5		$	(57	)	$	(10	)	$	70
Net credit-related charge-offs	$	113		$	22		$	11		$	—		$	—		$	146
Selected average balances:
Assets	$	30,609		$	5,937		$	4,903		$	9,343		$	5,466		$	56,258
Loans	30,353			5,446			4,840			36			(3		)	40,672
Deposits	19,069			16,930			2,924			653			95			39,671
Liabilities	19,040			16,895			2,909			10,838			868			50,550
Attributed equity	3,110			646			408			1,005			539			5,708
Statistical data:
Return on average assets (a)	1.75		%	(0.06		)%	0.43		%	N/M			N/M			0.50		%
Return on average attributed equity	17.25			(1.66		)	5.19			N/M			N/M			4.89
Net interest margin (b)	4.63			3.17			3.73			N/M			N/M			3.28
Efficiency ratio	36.86			89.14			77.57			N/M			N/M			64.47

							Wealth &
	Business			Retail			Institutional
Three Months Ended March 31, 2010	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	341		$	130		$	42		$	(105	)	$	8		$	416
Provision for loan losses	137			31			12			—			(5		)	175
Noninterest income	76			44			60			12			2			194
Noninterest expenses	162			154			73			2			13			404
Provision (benefit) for income taxes (FTE)	29			(4		)	6			(36		)	1			(4		)
Income from discontinued operations, net of tax	—			—			—			—			17			17
Net income (loss)	$	89		$	(7	)	$	11		$	(59	)	$	18		$	52
Net credit-related charge-offs	$	137		$	26		$	10		$	—		$	—		$	173
Selected average balances:
Assets	$	31,293		$	6,106		$	4,862		$	9,416		$	5,842		$	57,519
Loans	30,918			5,599			4,789			9			(2		)	41,313
Deposits	17,750			16,718			2,791			1,218			94			38,571
Liabilities	17,711			16,678			2,777			12,601			888			50,655
Attributed equity	3,159			589			357			919			1,840			6,864
Statistical data:
Return on average assets (a)	1.13		%	(0.17		)%	0.92		%	N/M			N/M			0.36		%
Return on average attributed equity	11.24			(4.86		)	12.50			N/M			N/M			(5.61		)
Net interest margin (b)	4.48			3.18			3.53			N/M			N/M			3.18
Efficiency ratio	38.72			88.44			73.18			N/M			N/M			66.45

							Wealth &
	Business			Retail			Institutional
Three Months Ended June 30, 2009	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	328		$	128		$	40		$	(101	)	$	9		$	404
Provision for loan losses	252			42			13			—			5			312
Noninterest income	50			46			73			124			5			298
Noninterest expenses	157			167			77			7			21			429
Provision (benefit) for income taxes (FTE)	(36		)	(17		)	8			8			(20		)	(57		)
Income from discontinued operations, net of tax	—			—			—			—			—			—
Net income (loss)	$	5		$	(18	)	$	15		$	8		$	8		$	18
Net credit-related charge-offs	$	211		$	29		$	8		$	—		$	—		$	248
Selected average balances:
Assets	$	37,521		$	6,693		$	4,965		$	12,320		$	2,757		$	64,256
Loans	36,760			6,115			4,776			3			(6		)	47,648
Deposits	14,827			17,666			2,599			5,669			22			40,783
Liabilities	15,110			17,639			2,593			21,484			277			57,103
Attributed equity	3,353			648			373			1,140			1,639			7,153
Statistical data:
Return on average assets (a)	0.05		%	(0.40		)%	1.21		%	N/M			N/M			0.11		%
Return on average attributed equity	0.58			(11.41		)	16.11			N/M			N/M			(1.25		)
Net interest margin (b)	3.58			2.90			3.29			N/M			N/M			2.73
Efficiency ratio	41.79			95.00			69.77			N/M			N/M			72.75

(a) Return on average assets is calculated based on the greater of average assets or average liabilities and attributed equity.

(b) Net interest margin is calculated based on the greater of average earning assets or average deposits and purchased funds.

FTE - Fully Taxable Equivalent

N/M - Not Meaningful

23

MARKET SEGMENT FINANCIAL RESULTS (unaudited)

Comerica Incorporated and Subsidiaries

																			Finance
(dollar amounts in millions)													Other						& Other
Three Months Ended June 30, 2010	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	211		$	164		$	81		$	12		$	43		$	19		$	(106	)	$	424
Provision for loan losses	40			27			(1		)	17			44			(5		)	4			126
Noninterest income	97			33			23			4			15			9			13			194
Noninterest expenses	181			110			65			12			20			8			1			397
Provision (benefit) for income taxes (FTE)	30			21			14			(4		)	(14		)	9			(31		)	25
Income from discontinued operations, net of tax	—			—			—			—			—			—			—			—
Net income (loss)	$	57		$	39		$	26		$	(9	)	$	8		$	16		$	(67	)	$	70
Net credit-related charge-offs	$	51		$	47		$	8		$	7		$	33		$	—		$	—		$	146
Selected average balances:
Assets	$	14,990		$	13,006		$	6,652		$	1,576		$	3,570		$	1,655		$	14,809		$	56,258
Loans	14,959			12,792			6,428			1,575			3,294			1,591			33			40,672
Deposits	18,005			11,951			5,316			404			2,195			1,052			748			39,671
Liabilities	17,982			11,876			5,308			392			2,227			1,059			11,706			50,550
Attributed equity	1,472			1,358			672			161			339			162			1,544			5,708
Statistical data:
Return on average assets (a)	1.17		%	1.17		%	1.54		%	(2.18		)%	0.89		%	3.90		%	N/M			0.50		%
Return on average attributed equity	15.44			11.38			15.29			(21.31		)	9.42			39.95			N/M			4.89
Net interest margin (b)	4.69			5.13			5.05			2.94			5.29			4.62			N/M			3.28
Efficiency ratio	58.22			55.91			62.32			76.90			37.84			30.48			N/M			64.47

																			Finance
													Other						& Other
Three Months Ended March 31, 2010	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	205		$	161		$	79		$	10		$	40		$	18		$	(97	)	$	416
Provision for loan losses	81			59			17			3			23			(3		)	(5		)	175
Noninterest income	102			36			20			3			10			9			14			194
Noninterest expenses	186			105			60			9			21			8			15			404
Provision (benefit) for income taxes (FTE)	14			11			8			—			(10		)	8			(35		)	(4		)
Income from discontinued operations, net of tax	—			—			—			—			—			—			17			17
Net income (loss)	$	26		$	22		$	14		$	1		$	16		$	14		$	(41	)	$	52
Net credit-related charge-offs	$	55		$	64		$	25		$	10		$	14		$	5		$	—		$	173
Selected average balances:
Assets	$	15,573		$	13,175		$	6,892		$	1,576		$	3,417		$	1,628		$	15,258		$	57,519
Loans	15,332			12,980			6,704			1,576			3,126			1,588			7			41,313
Deposits	17,068			11,927			4,957			361			1,973			973			1,312			38,571
Liabilities	17,044			11,846			4,941			347			2,010			978			13,489			50,655
Attributed equity	1,446			1,315			670			164			352			158			2,759			6,864
Statistical data:
Return on average assets (a)	0.55		%	0.67		%	0.84		%	0.17		%	1.85		%	3.50		%	N/M			0.36		%
Return on average attributed equity	7.09			6.68			8.66			1.60			17.97			36.09			N/M			(5.61		)
Net interest margin (b)	4.86			5.04			4.79			2.54			5.23			4.64			N/M			3.18
Efficiency ratio	60.64			53.08			60.36			72.04			43.87			29.12			N/M			66.45

																			Finance
													Other						& Other
Three Months Ended June 30, 2009	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	200		$	154		$	73		$	11		$	41		$	17		$	(92	)	$	404
Provision for loan losses	119			90			28			20			43			7			5			312
Noninterest income	92			32			21			3			13			8			129			298
Noninterest expenses	186			113			60			9			25			8			28			429
Provision (benefit) for income taxes (FTE)	(13		)	(10		)	1			(7		)	(20		)	4			(12		)	(57		)
Income from discontinued operations, net of tax	—			—			—			—			—			—			—			—
Net income (loss)	$	—		$	(7	)	$	5		$	(8	)	$	6		$	6		$	16		$	18
Net credit-related charge-offs	$	99		$	70		$	11		$	23		$	42		$	3		$	—		$	248
Selected average balances:
Assets	$	18,122		$	14,901		$	7,798		$	1,820		$	4,488		$	2,050		$	15,077		$	64,256
Loans	17,427			14,684			7,547			1,820			4,157			2,016			(3		)	47,648
Deposits	17,166			10,717			4,496			331			1,582			800			5,691			40,783
Liabilities	17,461			10,625			4,505			321			1,643			787			21,761			57,103
Attributed equity	1,568			1,358			694			182			415			157			2,779			7,153
Statistical data:
Return on average assets (a)	—		%	(0.19		)%	0.24		%	(1.78		)%	0.57		%	1.13		%	N/M			0.11		%
Return on average attributed equity	(0.01		)	(2.13		)	2.65			(17.76		)	6.17			14.71			N/M			(1.25		)
Net interest margin (b)	4.56			4.20			3.88			2.44			4.00			3.27			N/M			2.73
Efficiency ratio	63.83			60.67			63.92			66.24			47.75			30.99			N/M			72.75

(a) Return on average assets is calculated based on the greater of average assets or average liabilities and attributed equity.

(b) Net interest margin is calculated based on the greater of average earning assets or average deposits and purchased funds.

FTE - Fully Taxable Equivalent

N/M - Not Meaningful

24

RECONCILIATION OF NON-GAAP FINANCIAL MEASURES (unaudited)

Comerica Incorporated and Subsidiaries

	Six Months Ended June 30,
(dollar amounts in millions)	2010			2009
Net interest income (FTE)	$	840		$	790
Less:
Interest earned on excess liquidity (a)	5			2
Net interest income (FTE), excluding excess liquidity	$	835		$	788
Average earning assets	$	52,385		$	60,631
Less:
Average net unrealized gains on investment securities available-for-sale	71			226
Average earning assets for net interest margin (FTE)	52,314			60,405
Less:
Excess liquidity (a)	3,905			1,823
Average earning assets for net interest margin (FTE), excluding excess liquidity	$	48,409		$	58,582
Net interest margin (FTE)	3.23		%	2.63		%
Net interest margin (FTE), excluding excess liquidity	3.47			2.70
Impact of excess liquidity on net interest margin (FTE)	(0.24		)	(0.07		)

	2010						2009
	2nd Qtr			1st Qtr			4th Qtr			3rd Qtr			2nd Qtr
Net interest income (FTE)	$	424		$	416		$	398		$	387		$	404
Less:
Interest earned on excess liquidity (a)	2			2			1			2			1
Net interest income (FTE), excluding excess liquidity	$	422		$	414		$	397		$	385		$	403
Average earning assets	$	51,835		$	52,941		$	53,953		$	57,513		$	59,522
Less:
Average net unrealized gains on investment securities available-for-sale	80			62			107			102			239
Average earning assets for net interest margin (FTE)	51,755			52,879			53,846			57,411			59,283
Less:
Excess liquidity (a)	3,719			4,092			2,453			3,492			1,833
Average earning assets for net interest margin (FTE), excluding excess liquidity	$	48,036		$	48,787		$	51,393		$	53,919		$	57,450
Net interest margin (FTE)	3.28		%	3.18		%	2.94		%	2.68		%	2.73		%
Net interest margin (FTE), excluding excess liquidity	3.51			3.42			3.07			2.84			2.81
Impact of excess liquidity on net interest margin (FTE)	(0.23		)	(0.24		)	(0.13		)	(0.16		)	(0.08		)

(a) Excess liquidity represented by interest earned on and average balances deposited with the Federal Reserve Bank (FRB).

The net interest margin (FTE), excluding excess liquidity, removes interest earned on balances deposited with the FRB from net interest income (FTE) and average balances deposited with the FRB from average earning asssets from the numerator and denominator of the net interest margin (FTE) ratio, respectively.  Comerica believes this measurement provides meaningful information to investors, regulators, management and others of the impact on net interest income and net interest margin resulting from Comerica's short-term investment in low yielding instruments.

25

RECONCILIATION OF NON-GAAP FINANCIAL MEASURES (unaudited)

Comerica Incorporated and Subsidiaries

	June 30,			March 31,			December 31,			September 30,			June 30,
	2010			2010			2009			2009			2009
Tier 1 capital (a) (b)	$	6,371		$	6,311		$	7,704		$	7,735		$	7,774
Less:
Fixed rate cumulative perpetual preferred stock	—			—			2,151			2,145			2,140
Trust preferred securities	495			495			495			495			495
Tier 1 common capital (b)	$	5,876		$	5,816		$	5,058		$	5,095		$	5,139
Risk-weighted assets (a) (b)	$	60,037		$	60,792		$	61,815		$	63,355		$	67,124
Tier 1 common capital ratio (b)	9.79		%	9.57		%	8.18		%	8.04		%	7.66		%
Total shareholders’ equity	$	5,792		$	5,668		$	7,029		$	7,035		$	7,093
Less:
Fixed rate cumulative perpetual preferred stock	—			—			2,151			2,145			2,140
Goodwill	150			150			150			150			150
Other intangible assets	6			7			8			8			10
Tangible common equity	$	5,636		$	5,511		$	4,720		$	4,732		$	4,793
Total assets	$	55,885		$	57,106		$	59,249		$	59,590		$	63,630
Less:
Goodwill	150			150			150			150			150
Other intangible assets	6			7			8			8			10
Tangible assets	$	55,729		$	56,949		$	59,091		$	59,432		$	63,470
Tangible common equity ratio	10.11		%	9.68		%	7.99		%	7.96		%	7.55		%

(a) Tier 1 capital and risk-weighted assets as defined by regulation.

(b) June 30, 2010 Tier 1 capital and risk-weighted assets are estimated.

The Tier 1 common capital ratio removes preferred stock and qualifying trust preferred securities from Tier 1 capital as defined by and calculated in conformity with bank regulations.  The tangible common equity ratio removes preferred stock and the effect of intangible assets from capital and the effect of intangible assets from total assets.  Comerica believes these measurements are meaningful measures of capital adequacy used by investors, regulators, management and others to evaluate the adequacy of common equity and to compare against other companies in the industry.

26