Comerica Incorporated Third Quarter 2014Financial Review October 17, 2014 2 Safe Harbor Statement Any statements in this presentation that are not historical facts are forward-looking statements as defined in the Private Securities LitigationReform Act of 1995. Words such as “anticipates,” “believes,” “contemplates,” “feels,” “expects,” “estimates,” “seeks,” “strives,” “plans,” “intends,”“outlook,” “forecast,” “position,” “target,” “mission,” “assume,” “achievable,” “potential,” “strategy,” “goal,” “aspiration,” “opportunity,” “initiative,”“outcome,” “continue,” “remain,” “maintain,” “on course,” “trend,” “objective,” “looks forward,” “projects,” “models” and variations of such words andsimilar expressions, or future or conditional verbs such as “will,” “would,” “should,” “could,” “might,” “can,” “may” or similar expressions, as theyrelate to Comerica or its management, are intended to identify forward-looking statements. These forward-looking statements are predicated onthe beliefs and assumptions of Comerica's management based on information known to Comerica's management as of the date of thispresentation and do not purport to speak as of any other date. Forward-looking statements may include descriptions of plans and objectives ofComerica's management for future or past operations, products or services, and forecasts of Comerica's revenue, earnings or other measures ofeconomic performance, including statements of profitability, business segments and subsidiaries, estimates of credit trends and global stability.Such statements reflect the view of Comerica's management as of this date with respect to future events and are subject to risks anduncertainties. Should one or more of these risks materialize or should underlying beliefs or assumptions prove incorrect, Comerica's actual resultscould differ materially from those discussed. Factors that could cause or contribute to such differences are changes in general economic, politicalor industry conditions; changes in monetary and fiscal policies, including changes in interest rates; volatility and disruptions in global capital andcredit markets; changes in Comerica's credit rating; the interdependence of financial service companies; changes in regulation or oversight;unfavorable developments concerning credit quality; the effects of more stringent capital or liquidity requirements; declines or other changes in thebusinesses or industries of Comerica's customers; operational difficulties, failure of technology infrastructure or information security incidents; theimplementation of Comerica's strategies and business initiatives; Comerica's ability to utilize technology to efficiently and effectively develop,market and deliver new products and services; changes in the financial markets, including fluctuations in interest rates and their impact on depositpricing; competitive product and pricing pressures among financial institutions within Comerica's markets; changes in customer behavior; anyfuture strategic acquisitions or divestitures; management's ability to maintain and expand customer relationships; management's ability to retainkey officers and employees; the impact of legal and regulatory proceedings or determinations; the effectiveness of methods of reducing riskexposures; the effects of terrorist activities and other hostilities; the effects of catastrophic events including, but not limited to, hurricanes,tornadoes, earthquakes, fires and floods; changes in accounting standards and the critical nature of Comerica's accounting policies. Comericacautions that the foregoing list of factors is not exclusive. For discussion of factors that may cause actual results to differ from expectations, pleaserefer to our filings with the Securities and Exchange Commission. In particular, please refer to “Item 1A. Risk Factors” beginning on page 12 ofComerica's Annual Report on Form 10-K for the year ended December 31, 2013. Forward-looking statements speak only as of the date they aremade. Comerica does not undertake to update forward-looking statements to reflect facts, circumstances, assumptions or events that occur afterthe date the forward-looking statements are made. For any forward-looking statements made in this presentation or in any documents, Comericaclaims the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995.

3 Financial Summary $ in millions, except per share data ● 1Reflected a net benefit of $8MM, or $5MM after-tax, from certain actions, including a $32MM gain on the early redemption of debt, a $9MM contribution to the Comerica Charitable Foundation and other charges of $15MM. See slide 12 for further details. ● 2See Supplemental Financial Data slides for a reconciliation of non-GAAP financial measures ● 3Estimated 3Q14 2Q14 3Q13 Diluted income per common share $0.82 $0.80 $0.78 Impact from certain 3Q14 actions1 $0.03 -- -- Net interest income $414 $416 $412 Loan accretion 3 10 8 Provision for credit losses 5 11 8 Noninterest income 215 220 228 Noninterest expenses 3971 404 417 3Q14 actions1 8 -- -- Net income 154 151 147 Total average loans $47,159 $46,725 $44,094 Total average deposits 55,163 53,384 51,865 Tier 1 common capital ratio2 10.69%3 10.50% 10.72% Basel III Tier 1 common capital ratio2,3 10.4% 10.3% 10.4% Average diluted shares (millions) 185 186 187 4 Third Quarter 2014 Results $ in millions, except per share data ● 1Reflected a net benefit of $8MM, or $5MM after-tax, from certain actions, including a $32MM gain on the early redemption of debt, a $9MM contribution to the Comerica Charitable Foundation and other charges of $15MM. See slide 12 for further details. ● 2EPS based on diluted income per share ● 3Shares repurchased under the share repurchase program ● 43Q14 compared to 2Q14 Key Performance Drivers4  Broad-based average loan and deposit growth  Net interest income declined with lower accretion, partially offset by loan growth  Credit quality remained strong  Noninterest income reflects $3MM decline in FX income and $2MM decline in noncustomer-driven income  Expenses remained stable, excluding benefit from gain on debt redemption, charitable contribution and charges for efficiency-related projects  Share repurchases2, combined with dividends, returned $95 million to shareholders 3Q14 Change From2Q14 3Q13Total average loans 47,159 434 3,065 Total average deposits 55,163 1,779 3,298 Net interest income 414 (2) 2 Loan accretion 3 (7) (5) Provision for credit losses 5 (6) (3) Net loan charge-offs 3 (6) (16) Noninterest income 215 (5) (13) Customer-driven fee income 190 (3) (5) Noninterest expenses 397 (7) (20) 3Q14 actions1 8 -- -- Net income 154 3 7 Earnings per share (EPS)2 0.82 0.02 0.04 Shares repurchased3 1.2MM shares or $59MM

5 Diverse Footprint Drives Growth $ in billions 9.9 9.8 10.4 11.0 11.1 3Q13 4Q13 1Q14 2Q14 3Q14 Average Loans 10.3 10.5 10.9 10.7 10.6 3Q13 4Q13 1Q14 2Q14 3Q14 Average Deposits 14.0 14.4 14.8 15.4 15.5 3Q13 4Q13 1Q14 2Q14 3Q14 Average Loans 14.6 15.2 14.8 15.4 16.4 3Q13 4Q13 1Q14 2Q14 3Q14 Average Deposits 13.3 13.3 13.5 13.5 13.3 3Q13 4Q13 1Q14 2Q14 3Q14 Average Loans 20.5 20.5 20.6 20.7 21.2 3Q13 4Q13 1Q14 2Q14 3Q14 Average Deposits +12% +3% +11% +12% +4% Stable 6 Broad-based Average Loan GrowthPace of Growth Slowed with Seasonality and Economy 3Q14 compared to 2Q14 ● 1At period-end ● 2Utilization of commercial commitments as a percentage of total commercial commitments at period-end Total Loans($ in billions)  Loan yield impacted by lower accretion (-6bps), less nonaccrual interest collected & lease residual charge (-2bps), loan portfolio dynamics (-1 bps)  Commitments grew over $850MM to $55.1B1, driven by increases in nearly all business lines  Line utilization of 48.3%, down from 49.3%2  Loan pipeline increased with growth led by General Middle Market 44.1 44.1 45.1 46.7 47.2 47.9 47.7 3.44 3.58 3.39 3.31 3.22 3Q13 4Q13 1Q14 2Q14 3Q14 2Q14 3Q14 Loan Yields Average Balances Period-end Commercial Loans($ in billions) 2.9 3.2 3.2 3.5 3.2 3.6 3.21.6 1.1 0.9 1.3 1.6 2.0 1.927.8 27.7 28.4 29.9 30.2 31.0 30.8 3Q13 4Q13 1Q14 2Q14 3Q14 2Q14 3Q14 National Dealer Floor Plan Mortgage Banker Average Balances Period-end

7 Robust Average Deposit Growth of $1.8B or 3% Increases in Virtually All Business Lines 1Interest cost on interest-bearing deposits ● 23Q14 compared to 2Q14 ● 3At 9/30/14 Average Balances Period-end Strong Deposit Base($ in billions) 51.9 52.8 52.8 53.4 55.2 54.2 57.6 0.18 0.17 0.15 0.15 0.15 3Q13 4Q13 1Q14 2Q14 3Q14 2Q14 3Q14 Deposit Rates1 Total average deposits increased $1.8B2:  Noninterest-bearing deposits increased $1.3B to $25.3B, driven by+ $759MM General Middle Market+ $188MM Commercial Real Estate + $110MM Small Business+ $106MM Retail Banking  Interest-bearing deposits increased $515MM to $29.9B  About 2/3 of total deposits are commercial Loan to Deposit Ratio3 of 83% 8 Securities Portfolio StableContinue to Invest Prepayments in GNMA At 9/30/14 ● 1Estimated as of 9/30/14 ● 2Outlook as of 10/17/14. Prepayments include both scheduled principal amortization and mortgage prepayments MBS Portfolio:  Duration of 4.0 years1 • Duration extends to 4.7 years under a 200 bps instantaneous rate increase1  Net unrealized pre-tax loss of $22MM  Net unamortized premium of $56MM  Yields declined 6 bps due to a decrease of $1MM from retrospective adjustment to premium amortization in 2Q14  Expect prepayments of $350MM-$450MM for 4Q142  GNMA approximately 20% of MBS portfolio 9.0 9.0 8.9 9.0 9.0 9.1 9.1 9.4 9.4 9.3 9.4 9.4 9.5 9.5 2.41 2.46 2.42 2.35 2.29 3Q13 4Q13 1Q14 2Q14 3Q14 2Q14 3Q14 MBS Other MBS Yield Securities Portfolio($ in billions) Average Balances Period-end

9 Net Interest Income StableDecline in Accretion Partially Offset by Loan Growth 13Q14 compared to 2Q14 ● 2Lower securities yields due to the $1MM retrospective adjustment to premium amortization in 2Q14 Net Interest Income and Rate NIM1: $416MM 2Q14 2.78% -7+4+4-2-2-1 Loan Impacts:Loan accretionLoan growth1 additional day in 3Q14Lease residual value adj.Loan portfolio dynamicsInterest on nonaccrual loans -0.05-----0.01-0.01-- +2 Interest expense on debt +0.01 -1 Lower securities yields2 -0.01 +1 Excess reserves at the Fed -0.04 $414MM 3Q14 2.67% 8 23 12 10 3412 430 410 416 414 2.79 2.86 2.77 2.78 2.67 3Q13 4Q13 1Q14 2Q14 3Q14 Accretion NIM Net Interest Income($ in millions) 10 Continued Strong Credit QualityNet Charge-offs of 3 bps At 9/30/14 ● 1Criticized loans are consistent with regulatory defined Special Mention, Substandard, Doubtful and Loss loan classifications. 2,461 2,260 2,139 2,188 2,094 1.08 0.84 0.76 0.75 0.75 3Q13 4Q13 1Q14 2Q14 3Q14 NPAs as a Percentage of Total Loans + ORE Net Loan Charge-offs($ in millions) Criticized Loans1($ in millions) Allowance for Loan Losses($ in millions) 604 598 594 591 592 1.3 1.6 1.8 1.7 1.7 3Q13 4Q13 1Q14 2Q14 3Q14 NPL Coverage 19 13 12 9 3 18 12 10 8 3 3Q13 4Q13 1Q14 2Q14 3Q14 NCO Ratio Provision decreased to $5MM  Nonperforming Assets (NPAs) of $357MM  Foreclosed Property of $11MM  Troubled Debt Restructurings (TDRs) of $126MM Credit Quality (In basis points)

11 Noninterest Income 3Q14 compared to 2Q14 ● 1Customer-driven fee income includes service charges on deposit accounts, fiduciary income, commercial lending fees, letter of credit fees, card fees, foreign exchange income, brokerage fees and customer-driven components of other noninterest income. Customer-driven fee income decreased $3MM: - $3MM Foreign Exchange Income - $2MM Investment Banking + $3MM Commercial Lending Fees Noncustomer-driven income decreased $2MM: - $1MM Net Securities Losses 195 190 184 193 190 33 29 24 27 25 228 219 208 220 215 3Q13 4Q13 1Q14 2Q14 3Q14 Customer-DrivenNoncustomer-Driven 1 Noninterest Income ($ in millions) 12 Continued Tight Expense ControlActions Taken Intended to Drive Continued Efficiency 3Q14 compared to 2Q14 ● 1Outlook as of 10/17/14● 2Outlook as of 10/17/14, based on efficiency-related & other actions included above, which are expected to be fully implemented over the next 12 months. 397 (8) 52 - 417 473 406 404 3Q13 4Q13 1Q14 2Q14 3Q14 Impact of 3Q14 Actions4Q13 Litigation-related Expense Noninterest Expenses($ in millions) 2H14 Actions ($ in millions) 3Q14 4Q141Gain on early redemption of debt (32)Charitable Foundation donation 9 Efficiency-related actions:Real estate optimization 8 5-7Severance 6Other 1 Total (8) 5-7 Run rate savings ~$12-14MM by YE15 to partially offset regulatory & technology headwinds2 Expenses Included $8MM Net Benefit From Actions Taken in 3Q14 Excluding actions, noninterest expenses increased $1MM: + Salaries & Benefits (1 additional day)+ Occupancy Expense- Litigation-related Expenses

13 Active Capital Management 1Shares repurchased under share repurchase program ● 2See Supplemental Financial Data slides for reconciliation of non-GAAP financial measures ● 3Outlook as of 10/17/14 2014 Capital Plan target3:  Up to $236MM share repurchases over four quarters (2Q14 through 1Q15)• $59MM or 1.2MM shares repurchased in 2Q14• $59MM or 1.2MM shares repurchased in 3Q14  Increased quarterly dividend 5% to $0.20 per share in 2Q14  3Q14 Shareholder payout ratio of 62% 3Q14 Capital Actions:  Called $150MM sub-debt at par in July  Issued $250MM sub-debt at 3.8% in July 183.7 182.3 181.7 181.0 180.2 $34.37 $35.64 $36.50 $37.12 $37.65 3Q13 4Q13 1Q14 2Q14 3Q14 Tangible Book Value Per Share Common Shares Outstanding (in MM) 19% 21% 23% 24% 28% 58% 53% 43%47% 79% 76% 67% 2011 2012 2013 YTD 2014 Dividends Share RepurchasesShareholder Payout Ratio1 2 14 Management 2014 OutlookAssuming Continuation of Current Economic & Low Rate Environment Outlook as of 10/17/14 FY14 compared to FY13 unchanged, except for: Average loans Moderate Growth of ~5% (previously 4-6%)• Growth is now expected to be in the middle of the range Net interest income Modestly Lower• Reduction in purchase accounting accretion to ~$30MM (previously $25-30MM) 4Q14 compared to 3Q14 Average loans Slight Growth• 4Q14 Mortgage Banker Finance seasonally lower• 4Q14 National Dealer seasonally higher• Small increases in remaining businesses with continued focus on pricing and structure discipline Net interest income Slight Growth• 4Q14 purchase accounting accretion of ~$5MM• Loan growth approximately offsets continued pressure from low rate environment Provision Remains Low• Similar to provisions in 1H14 Noninterest income Relatively Stable• Stable customer-driven income• Decline in noncustomer noninterest income Noninterest expenses Higher (from 3Q14 of $397MM)• 3Q14 included $8MM net benefit from actions taken• 4Q14 actions of ~$5-7MM• Higher technology and consulting expenses and seasonal increase in benefits expense

Appendix 16 Loans by Business and Market Average $ in billions  Middle Market: Serving companies with revenues generally between $20-$500MM  Corporate Banking: Serving companies (and their U.S. based subsidiaries) with revenues generally over $500MM  Small Business: Serving companies with revenues generally under $20MM By Line of Business 3Q14 2Q14 3Q13 Middle MarketGeneralEnergyNational Dealer ServicesEntertainmentTech. & Life SciencesEnvironmental Services $13.63.35.50.62.60.9 $13.73.25.70.62.50.9 $13.22.94.90.62.00.8 Total Middle Market $26.5 $26.6 $24.4 Corporate BankingUS BankingInternational 2.81.8 2.81.7 2.71.7 Mortgage Banker Finance 1.6 1.3 1.6 Commercial Real Estate 4.2 4.1 3.8 BUSINESS BANK $36.9 $36.5 $34.2 Small Business 3.7 3.6 3.6 Retail Banking 1.8 1.8 1.7 RETAIL BANK $5.5 $5.4 $5.3 Private Banking 4.8 4.8 4.6 WEALTH MANAGEMENT $4.8 $4.8 $4.6 TOTAL $47.2 $46.7 $44.1 By Market 3Q14 2Q14 3Q13 Michigan $13.3 $13.5 $13.3 California 15.5 15.4 14.0 Texas 11.1 11.0 9.9 Other Markets 7.3 6.8 6.9 TOTAL $47.2 $46.7 $44.1

17 Deposits by Business and Market Average $ in billions  Middle Market: Serving companies with revenues generally between $20-$500MM  Corporate Banking: Serving companies (and their U.S. based subsidiaries) with revenues generally over $500MM  Small Business: Serving companies with revenues generally under $20MM By Line of Business 3Q14 2Q14 3Q13 Middle MarketGeneralEnergyNational Dealer ServicesEntertainmentTech. & Life SciencesEnvironmental Services $15.30.50.20.15.90.1 $14.60.50.20.15.60.1 $14.00.50.20.15.10.2 Total Middle Market $22.1 $21.1 $20.1 Corporate BankingUS BankingInternational 2.71.8 2.61.7 2.41.8 Mortgage Banker Finance 0.5 0.5 0.6 Commercial Real Estate 1.7 1.5 1.4 BUSINESS BANK $28.8 $27.4 $26.3 Small Business 2.8 2.7 2.7 Retail Banking 19.0 19.0 18.6 RETAIL BANK $21.8 $21.7 $21.3 Private Banking 4.2 3.8 3.8 WEALTH MANAGEMENT $4.2 $3.8 $3.8 Finance/ Other 0.4 0.5 0.5 TOTAL $55.2 $53.4 $51.9 By Market 3Q14 2Q14 3Q13 Michigan $21.2 $20.7 $20.5 California 16.4 15.4 14.6 Texas 10.6 10.7 10.3 Other Markets 6.6 6.1 6.0 Finance/ Other 0.4 0.5 0.5 TOTAL $55.2 $53.4 $51.9 18 Mortgage Banker Finance Average Deposits($ in millions) Average Loans($ in millions) 40+ years’ experience with reputation for consistent, reliable approach  Provide short-term warehouse financing: bridge from origination of residential mortgage until sale into end market  Extensive backroom provides collateral monitoring and customer service  Focus on full banking relationships 360 481 52 3 551 6 37 513 372 399 4 41 454 49 7 62 5 645 665 643 566 565 516 516 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 425 707 943 1 ,101 566 61 4 923 1,53 5 1,48 3 1,50 7 1,99 6 2,09 4 1,73 7 1,81 5 1,60 5 1,10 9 886 1,31 9 1,59 5 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 At 9/30/14

19 National Dealer Services At 9/30/14 ● 1Other includes obligations where a primary franchise is indeterminable (rental car and leasing companies, heavy truck, recreational vehicles, and non-floor plan loans) Toyota/Lexus16% Honda/Acura 13% Ford 9% GM 10% Chrysler 9% Mercedes 3%Nissan/ Infiniti 7% Other European 11% Other Asian 12% Other110% Franchise Distribution(Based on period-end loan outstandings) Geographic DispersionCalifornia 63% Texas 9%Michigan 17% Other 11% Average Loans($ in billions)  65+ years of Floor Plan lending, with 20+ years on a national basis  Top tier strategy  Focus on “Mega Dealer” (five or more dealerships in group)  Excellent credit quality  Robust monitoring of company inventory and performance 1.9 1.7 1.3 1.5 1.9 2.3 2.3 2.5 2.8 3.1 2.9 3.2 3.2 3.5 3.2 3.8 3.6 3.1 3.4 3.8 4.3 4.3 4.6 4.9 5.1 4.9 5.3 5.3 5.7 5.5 1Q112Q113Q114Q111Q122Q123Q124Q121Q132Q133Q134Q131Q142Q143Q14 Floor Plan 20 Energy At 9/30/14  30+ years’ experience through the cycles  Focus on middle market companies  Excellent credit quality  Deep relationships with significant ancillary noncredit products Average Loans($ in millions) 1,29 6 1,14 9 1,19 6 1,26 9 1,42 3 1,45 6 1,63 5 1,94 7 2,30 5 2,45 2 2,64 1 2,85 1 3,00 2 2,95 1 2,89 5 2,75 2 2,98 2 3,23 6 3,33 2 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 152 233 430 444 50 1 493 492 865 686 567 533 512 411 48 8 529 60 8 493 528 54 0 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 Average Deposits($ in millions) Natural Gas Oil MixedMidstream13% Service17% Exploration & Production 70% Diverse Customer Base(Based on period-end loan outstandings)

21 Technology and Life Sciences At 9/30/14  20+ year history  Products and services tailored to meet the needs of emerging companies throughout their lifecycle  Strong relationships with top-tier investors  National business headquartered in Palo Alto, CA, operating from 13 offices in the U.S. and Toronto  Top notch relationship managers with extensive industry expertise Average Loans($ in billions) 1.1 1.1 1.1 1.2 1.2 1.2 1 .3 1.5 1.6 1. 7 1.8 1.9 2. 0 1.9 2.0 2. 1 2.3 2. 5 2.6 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 3.3 3.4 3.3 3.5 3. 7 4.1 4.2 4.4 4 .7 5.1 5.2 5.2 5.0 5.0 5.1 5.2 5 .7 5.6 5.9 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 Average Deposits($ in billions) 22 Commercial Real Estate Line of Business At 9/30/14 ● 1Includes CRE line of business loans not secured by real estate 5.7 5.4 5.1 4.8 4.4 4.0 4.4 4.6 4.4 4.3 3.9 3.7 3.7 3.8 3.8 3.8 4 .0 4.1 4.2 1Q1 0 2Q1 0 3Q1 0 4Q1 0 1Q1 1 2Q1 1 3Q1 1 4Q1 1 1Q1 2 2Q1 2 3Q1 2 4Q1 2 1Q1 3 2Q1 3 3Q1 3 4Q1 3 1Q1 4 2Q1 4 3Q1 4 Commercial MortgagesReal Estate ConstructionCommercial & Other Average Loans($ in billions) 4.9 5.2 5.4 5.6 6.0 3Q13 4Q13 1Q14 2Q14 3Q14 Commitments($ in billions; Based on period-end)  160+ years experience with focus on well-established developers, primarily in our footprint  Provide construction and mini-perm mortgage financing  Real Estate Construction average loans up for the past 8 quarters +23% 1

23 Shared National Credit Relationships At 9/30/14 ● Shared National Credit (SNC): Facilities greater than $20 million shared by three or more federally supervised financial institutions which are reviewed by regulatory authorities at the agent bank level. Period-end Loans of $10.4B Commercial Real Estate$0.6B 6% Corporate $2.8B 26% General$2.4B 23%National Dealer $0.4B 4% Energy$3.0B 29% Entertainment$0.3B 3% Tech. & Life Sciences$0.3B 3% Environmental Services $0.4B 4% Mortgage Banker$0.2B 2% = Total Middle Market (66%)  Approximately 870 borrowers  Strategy: Pursue full relationships with ancillary business  Comerica is agent for approx. 18%  Adhere to same credit underwriting standards as rest of loan book  Credit quality mirrors total portfolio 24 Government Card Programs At 9/30/14 ● 1Source: the Nilson Report July 2014 ● 2Based on a 2013 survey conducted by KRC Research ● 3Checks eliminated since December 2010. Source: U.S. Department of the Treasury Growing Average Noninterest-Bearing Deposits($ in millions) 185 290 532 650 720 948 1,221 1,433 2007 2008 2009 2010 2011 2012 2013 2014YTD US Treasury ProgramState Card Programs  #1 prepaid card issuer1 in US  Service 32 state and local government benefit programs  Service US Treasury DirectExpress Program:• Exclusive provider of prepaid debit cards since 2008; contract extended to January 2020• Over 5 million cards registered• 94% of Direct Express card holders report they are totally satisfied2• Nearly 8MM monthly benefit checks eliminated, resulting in significant taxpayer savings3

25 Maintaining Focus on Long-Term GoalsMoving Toward Goals, Despite Prolonged Low Rate Environment Goal as of 10/17/14 Efficiency Ratio Return on Average Assets (ROA) 71.2% 67.9% 67.3% 65.8% 63.4% 62.9% 2011 2012 2013 1Q14 2Q14 3Q14 0.69% 0.83% 0.85% 0.86% 0.93% 0.93% 2011 2012 2013 1Q14 2Q14 3Q14 Long-TermGoal: Above 1.30%Long-TermGoal: Below 60% 26 Factors Expected to Drive Long-Term Efficiency Ratio Goal Goal as of 10/17/14 2013 Long-Term Goal Efficiency Ratio:67% Efficiency Ratio:<60% Expense Growth of 0 - 2% Fee Income Growth of 2 - 4% Loan Growth of 3 - 5% • Increase cross-sell penetration • Collaboration between businesses Focused growth:• Target markets • Allocation of resources to faster growing businesses • Relationship driven • Normalized rates not necessary to reach long-term goal • Continued focus on operating leverage ≈1% ≈2% Normal (≈3.5%) Fed Funds

27 Holding Company Debt Rating As of 10/9/14 ● Source: SNL Financial ● Debt Ratings are not a recommendation to buy, sell, or hold securities Senior Unsecured/Long-Term Issuer Rating S&P Moody’s Fitch BB&T A- A2 A+ BOK Financial A- A2 A Comerica A- A3 A M&T Bank A- A3 A- KeyCorp BBB+ Baa1 A- Fifth Third BBB+ Baa1 A SunTrust BBB Baa1 BBB+ Huntington BBB Baa1 A- Regions Financial BBB- Ba1 BBB Zions Bancorporation BBB- Ba1 BBB- First Horizon National Corp BB+ Baa3 BBB- Synovus Financial Corp BB- B1 BB Wells Fargo & Company A+ A2 AA- U.S. Bancorp A+ A1 AA- JP Morgan A A3 A+ PNC Financial Services Group A- A3 A+ Bank of America A- Baa2 A Pee r Ba nks Larg e Ba nks Supplemental Financial DataReconciliation of non-GAAP financial measures with financial measures defined by GAAP ($ in millions) 28 The Tier 1 common capital ratio removes preferred stock and qualifying trust preferred securities from Tier 1 capital as defined by and calculated in conformity with bank regulations. The tangible common equity ratio removes preferred stock and the effect of intangible assets from capital and the effect of intangible assets from total assets. Tangible common equity per share of common stock removed the effect of intangible assets from common shareholders equity per share of common stock.The Corporation believes these measurements are meaningful measures of capital adequacy used by investors, regulators, management and others to evaluate the adequacy of common equity and to compare against other companies in the industry.1Tier 1 Capital and risk-weighted assets as defined and calculated in accordance with regulation.2September 30, 2014 Tier 1 Capital and Risk-Weighted assets are estimated. 9/30/14 6/30/14 3/31/14 12/31/13 9/30/13 Tier 1 and Tier 1 common capital1,2Risk-weighted assets1,2Tier 1 and Tier 1 common capital ratio2 7,10566,48110.69% 7,02766,91110.50% 6,96265,78810.58% 6,89564,82510.64% 6,86264,02710.72% Common shareholders’ equityLess: GoodwillLess: Other intangible assets $7,43363515 $7,36963515 $7,28363516 $7,15063517 $6,96663518Tangible common equity $6,783 $6,719 $6,632 $6,498 $6,313Total assetsLess: GoodwillLess: Other intangible assets $68,88763515 $65,32563515 $65,68163516 $65,22463517 $64,66763518Tangible assets $68,237 $64,675 $65,030 $64,572 $64,014Common equity ratio 10.79% 11.28% 11.09% 10.97% 10.78%Tangible common equity ratio 9.94 10.39 10.20 10.07 9.87 Common shareholders’ equity $7,433 $7,369 $7,283 $7,150 $6,966Tangible common equity $6,783 $6,719 $6,632 $6,498 $6,313Shares of common stock outstanding (in millions) 180 181 182 182 184 Common shareholders’ equity per share of common stock $41.26 $40.72 $40.09 $39.22 $37.93Tangible common equity per share of common stock 37.65 37.12 36.50 35.64 34.37

Supplemental Financial DataTier 1 Common Equity under Basel III ($ in millions) 29 The Tier 1 common capital ratio removes preferred stock and qualifying trust preferred securities from Tier 1 capital as defined by and calculated in conformity with bank regulations. The Basel III Tier 1 common capital ratio further adjusts Tier 1 common capital and risk-weighted assets to account for the final rule approved by U.S. banking regulators in July 2013 for the U.S. adoption of the Basel III regulatory capital framework. The final Basel III capital rules are effective January 1, 2015 for banking organizations subject to the standardized approach. The Corporation believes these measurements are meaningful measures of capital adequacy used by investors, regulators, management and others to evaluate the adequacy of common equity and to compare against other companies in the industry.1Tier 1 Capital and risk-weighted assets as defined in accordance with regulation.2Estimated ratios based on the standardized approach in the final rule, as fully phased-in, and excluding most elements of accumulated other comprehensive income (AOCI).3September 30, 2014 Tier 1 Capital and Risk-Weighted assets are estimated. Basel III Tier 1 Common Capital Ratio 9/30/14 6/30/14 3/31/14 12/31/13 9/30/13 Tier 1 common capital3Basel III adjustments2 $7,105(1) $7,027(1) $6,962(2) $6,895(6) $6,862(4) Basel III Tier 1 common capital2 $7,104 $7,026 $6,960 $6,889 $6,858 Risk-weighted assets1,3Basel III adjustments2 $66,4811,627 $66,9111,594 $65,7881,590 $64,8251,754 $64,0271,726Basel III risk-weighted assets2 $68,108 $68,505 $67,378 $66,579 $65,753 Tier 1 common capital ratio3Basel III Tier 1 common capital ratio2 10.7%10.4% 10.5%10.3% 10.6%10.3% 10.6%10.3% 10.7%10.4%