COMERICA REPORTS FIRST QUARTER 2012 RESULTS

Net Income of $130 Million Up 36 Percent From Fourth Quarter 2011

Average Total Loans Increased - Driven by a $1.2 Billion, 5 Percent Increase in Commercial Loans

Customer-Driven Fee Income Increased 6 Percent

DALLAS/April 17, 2012 -- Comerica Incorporated (NYSE: CMA) today reported first quarter 2012 net income of $130 million, an increase of $34 million compared to $96 million for the fourth quarter 2011.

(dollar amounts in millions, except per share data)	1st Qtr '12				4th Qtr '11				1st Qtr '11
Net interest income	$	443			$	444			$	395
Provision for loan losses	23				19				49
Noninterest income	206				182				207
Noninterest expenses	448				478			(a)	415
Provision for income taxes	48				33				35
Net income	130				96				103
Net income attributable to common shares	129				95				102
Diluted income per common share	0.66				0.48			(a)	0.57
Average diluted shares (in millions)	196				197				178
Tier 1 common capital ratio (c)	10.33		%	(b)	10.37		%		10.35		%
Tangible common equity ratio (c)	10.21				10.27				10.43

(a) Included restructuring expenses of $37 million ($23 million, after tax; $0.12 per diluted share) in fourth quarter 2011, associated with the acquisition of Sterling on July 28, 2011.

(b) March 31, 2012 ratio is estimated.

(c) See Reconciliation of Non-GAAP Financial Measures.

"We were pleased by the continued growth in average total loans in the first quarter, driven by a $1.2 billion, or 5 percent, increase in average commercial loans," said Ralph W. Babb Jr., chairman and chief executive officer. "The increase in average commercial loans, when compared to the fourth quarter of 2011, was broad-based, across a majority of business lines and all major markets.

"Noninterest income increased $24 million, driven by a $10 million, or 6 percent, increase in customer-driven fees, offsetting the headwinds of regulatory reform.

"We continue to approach capital management from a position of strength," said Babb. "As we announced on March 14, 2012, the Federal Reserve did not object to our capital plan and the capital distributions contemplated in the plan. The capital plan, which was approved by our board of directors, provides for up to $375 million in equity repurchases from the first quarter 2012 through the first quarter 2013. We had $33 million in equity repurchases under the share repurchase program in the first quarter 2012. A dividend proposal that would increase the quarterly dividend 50 percent, from 10 cents per share to 15 cents per share, will be considered by our board at its next meeting on April 24, 2012."

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 2

First Quarter 2012 Highlights Compared to Fourth Quarter 2011

• Net income of $130 million, or $0.66 per fully diluted share, increased 36 percent compared to fourth quarter 2011.

• Average total loans increased $815 million, or 2 percent, primarily reflecting an increase of $1.2 billion, or 5 percent, in commercial loans, partially offset by a decrease of $352 million, or 3 percent, in commercial real estate loans (commercial mortgage and real estate construction loans). The increase in commercial loans was broad-based, primarily driven by increases in National Dealer Services, Energy, Global Corporate Banking, Middle Market Banking, and Technology and Life Sciences.

• Period-end loans increased $333 million, or 1 percent, from December 31, 2011 to March 31, 2012, primarily reflecting an increase of $644 million, or 3 percent, in commercial loans, partially offset by a $276 million, or 2 percent, decrease in commercial real estate loans. The increase in period-end commercial loans was primarily driven by increases in National Dealer Services, Middle Market Banking, Global Corporate Banking and Energy, partially offset by decreases in Mortgage Banker Finance and Small Business Banking.

• Average deposits increased $532 million, or 1 percent, primarily reflecting an increase of $461 million in noninterest-bearing deposits. Period end deposits increased $1.5 billion from December 31, 2011 to a record $49.3 billion at March 31, 2012, while funding costs continued to decline. The increase in average deposits primarily reflected increases in Global Corporate Banking, the Financial Services Division, Technology and Life Sciences, and Private Banking, partially offset by decreases in Small Business Banking and Energy.

• Credit quality continued to improve in the first quarter 2012. Net credit-related charge-offs of $45 million decreased for the eleventh consecutive quarter. The provision for loan losses was $23 million in the first quarter 2012, compared to $19 million in the fourth quarter 2011.

• Noninterest income increased to $206 million in the first quarter 2012, compared to $182 million for the fourth quarter 2011. The $24 million increase in large part resulted from increases in customer-driven fee income categories.

• Noninterest expenses decreased $30 million to $448 million in the first quarter 2012, compared to the fourth quarter 2011. The decrease was primarily due to a $37 million decrease in merger and restructuring charges related to the Sterling acquisition.

• As previously announced, the Federal Reserve completed its review of Comerica's 2012 Capital Plan in the first quarter 2012 and did not object to the capital distributions contemplated in the plan, including up to $375 million of equity repurchases in the five-quarter period ending March 31, 2013 and a 50 percent increase in the quarterly dividend. Comerica repurchased 1.1 million shares of common stock under the share repurchase program in the first quarter 2012.

Net Interest Income

(dollar amounts in millions)	1st Qtr '12			4th Qtr '11			1st Qtr '11
Net interest income	$	443		$	444		$	395
Net interest margin	3.19		%	3.19		%	3.25		%
Selected average balances:
Total earning assets	$	56,186		$	55,676		$	49,347
Total investment securities	9,889			9,781			7,311
Total loans	42,269			41,454			39,551
Total deposits	48,311			47,779			40,598
Total noninterest-bearing deposits	19,637			19,176			15,459

• Net interest income of $443 million in the first quarter 2012 decreased $1 million compared to the fourth quarter 2011, as the benefit from a $510 million increase in average earning assets ($7 million) and lower funding costs ($2 million) was offset by lower loan yields ($5 million) and one less day in the quarter ($5 million). The lower loan yields reflected a shift in the average loan portfolio mix, largely due to the decrease in average commercial real estate loans and the increase in average commercial loans. Accretion of the purchase discount on the acquired Sterling loan portfolio was $25 million in the first quarter 2012, compared to $26 million in the fourth quarter 2011. For the remainder of 2012, $35 million

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 3

to $45 million of accretion is expected to be recognized.

• Average earning assets increased $510 million in the first quarter 2012 compared to the fourth quarter 2011, primarily reflecting increases of $815 million in average loans and $108 million in average investment securities available-for-sale, partially offset by a $417 million decrease in average Federal Reserve Bank deposits.

• Average deposits increased $532 million in the first quarter 2012, compared to the fourth quarter 2011, primarily due to a $461 million increase in average noninterest-bearing deposits.

Noninterest Income

Noninterest income was $206 million for the first quarter 2012, compared to $182 million for the fourth quarter 2011. The $24 million increase primarily resulted from a $10 million, or 6 percent, increase in customer-driven fee income and a $9 million increase in net securities gains. The increase in customer-driven fee income included increases in service charges on deposit accounts ($4 million), investment banking fees ($3 million), fiduciary income ($2 million) and commercial lending fees ($2 million). The increase in net securities gains reflected an increase of $4 million in gains from redemptions of auction-rate securities in the first quarter 2012, when compared to fourth quarter 2011, and $5 million in charges in the fourth quarter 2011 related to a derivative contract tied to the conversion rate of Visa Class B shares.

Noninterest Expenses

Noninterest expenses totaled $448 million in the first quarter 2012, a decrease of $30 million compared to $478 million in the fourth quarter 2011. The decrease in noninterest expenses was primarily due to decreases in merger and restructuring charges ($37 million), net occupancy expense ($6 million), and salaries expense ($4 million), partially offset by increases in employee benefits expense ($8 million), primarily due to an increase in pension expense, and litigation and legal expenses ($5 million), included in other noninterest expenses. The decrease in net occupancy expense in part reflected savings related to increased efficiency in space utilization. Restructuring charges of approximately $40 million are expected to be incurred for the remainder of 2012, with $5 million to $10 million expected in second quarter 2012.

Credit Quality

(dollar amounts in millions)	1st Qtr '12			4th Qtr '11			1st Qtr '11
Net credit-related charge-offs	$	45		$	60		$	101
Net credit-related charge-offs/Average total loans	0.43		%	0.57		%	1.03		%
Provision for loan losses	$	23		$	19		$	49
Provision for credit losses on lending-related commitments	(1		)	(1		)	(3		)
Total provision for credit losses	22			18			46
Nonperforming loans (a)	856			887			1,030
Nonperforming assets (NPAs) (a)	923			981			1,104
NPAs/Total loans and foreclosed property	2.14		%	2.29		%	2.81		%
Loans past due 90 days or more and still accruing	$	50		$	58		$	72
Allowance for loan losses	704			726			849
Allowance for credit losses on lending-related commitments (b)	25			26			32
Total allowance for credit losses	729			752			881
Allowance for loan losses/Total loans (c)	1.64		%	1.70		%	2.17		%
Allowance for loan losses/Nonperforming loans	82			82			82

(a) Excludes loans acquired with credit impairment.

(b) Included in "Accrued expenses and other liabilities" on the consolidated balance sheets.

(c) Reflects the impact of acquired loans, which were initially recorded at fair value, with no related allowance for loan losses.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 4

"Credit quality continued to improve in the first quarter," said Babb. "Net charge-offs, which decreased $15 million to $45 million in the first quarter, are at the lowest level since the third quarter of 2007. The provision for loan losses was relatively stable. Our expectation is that we will continue to see the provision and net-charge offs at these levels for the remainder of the year assuming the current level of economic growth is sustained."

• Net credit-related charge-offs decreased $15 million to $45 million in the first quarter 2012, from $60 million in the fourth quarter 2011. The decrease in net credit-related charge-offs was broad-based, spread across many business lines.

• The provision for loan losses was $23 million in the first quarter 2012, compared to $19 million in the fourth quarter 2011. The change in the provision for loan losses reflects increased loan volumes.

• Internal watch list loans continued the downward trend, declining $261 million in the first quarter 2012, to $4.2 billion at March 31, 2012. Nonperforming assets decreased $58 million to $923 million at March 31, 2012.

• During the first quarter 2012, $69 million of borrower relationships over $2 million were transferred to nonaccrual status, a decrease of $30 million from the fourth quarter 2011.

• The allowance for loan losses to total loans ratio was 1.64 percent and 1.70 percent at March 31, 2012 and December 31, 2011, respectively.

Balance Sheet and Capital Management

Total assets and common shareholders' equity were $62.6 billion and $7.0 billion, respectively, at March 31, 2012, compared to $61.0 billion and $6.9 billion, respectively, at December 31, 2011. There were approximately 197 million common shares outstanding at March 31, 2012. Comerica repurchased $33 million of common stock (1.1 million shares) under the share repurchase program during the first quarter 2012.

The Federal Reserve completed its review of Comerica's 2012 Capital Plan in March 2012 and did not object to the capital distributions contemplated in the plan. The capital plan provides for up to $375 million in equity repurchases for the five-quarter period ending March 31, 2013. The capital plan, which was approved by Comerica's Board of Directors, further contemplates a 50 percent increase in Comerica's quarterly dividend, from 10 cents per share to 15 cents per share. The dividend proposal will be considered by the Board at its April 24, 2012 meeting. In addition, the capital plan includes the authority to redeem the remaining $25 million of trust preferred securities outstanding as of March 31, 2012.

Comerica's tangible common equity ratio was 10.21% at March 31, 2012, a decrease of 6 basis points from December 31, 2011. The estimated Tier 1 common capital ratio decreased 4 basis points, to 10.33% at March 31, 2012, from December 31, 2011.

Full-Year 2012 Outlook Compared to Full-Year 2011

For 2012, management expects the following, assuming a continuation of the current economic environment:

• Average loans increasing moderately.

• Net interest income increasing moderately.

• Net credit-related charge-offs and provision for credit losses declining.

• Noninterest income relatively stable.

• Noninterest expenses relatively stable.

• Effective tax rate of approximately 27 percent.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 5

Business Segments

Comerica's operations are strategically aligned into three major business segments: the Business Bank, the Retail Bank and Wealth Management. The Finance Division is also reported as a segment. The financial results below are based on the internal business unit structure of the Corporation and methodologies in effect at March 31, 2012 and are presented on a fully taxable equivalent (FTE) basis. The accompanying narrative addresses first quarter 2012 results compared to fourth quarter 2011.

The following table presents net income (loss) by business segment.

(dollar amounts in millions)	1st Qtr '12					4th Qtr '11					1st Qtr '11
Business Bank	$	206		89	%	$	201		94	%	$	167		93	%
Retail Bank	14			6		10			4		(2		)	(1	)
Wealth Management	11			5		5			2		14			8
	231			100	%	216			100	%	179			100	%
Finance	(92		)			(94		)			(75		)
Other (a)	(9		)			(26		)			(1		)
Total	130					$	96				$	103

(a) Includes discontinued operations and items not directly associated with the three major business segments or the Finance Division.

Business Bank

(dollar amounts in millions)	1st Qtr '12		4th Qtr '11			1st Qtr '11
Net interest income (FTE)	$	379	$	383		$	341
Provision for loan losses	1		(4		)	18
Noninterest income	81		73			77
Noninterest expenses	159		161			160
Net income	206		201			167
Net credit-related charge-offs	28		32			73
Selected average balances:
Assets	33,184		32,151			30,092
Loans	32,240		31,257			29,609
Deposits	23,997		23,296			20,084

• Average loans increased $983 million, primarily due to increases in National Dealer Services, Energy, Global Corporate Banking, Technology and Life Sciences, and Middle Market, partially offset by a decline in Commercial Real Estate.

• Average deposits increased $701 million, primarily due to increases in the Financial Services Division, Global Corporate Banking, and Technology and Life Sciences, partially offset by a decline in Energy.

• Net interest income decreased $4 million, primarily due to one less day in the quarter. The benefit from increases in average loan balances and lower deposit rates was offset by an increase in net funds transfer pricing (FTP) funding costs and lower loan yields.

• The provision for loan losses increased $5 million, primarily reflecting increases in Middle Market and Commercial Real Estate, partially offset by a decrease in Technology and Life Sciences.

• Noninterest income increased $8 million, primarily reflecting increases in service charges on deposit accounts, commercial lending fees, warrant income and customer derivative income.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 6

Retail Bank

(dollar amounts in millions)	1st Qtr '12		4th Qtr '11		1st Qtr '11
Net interest income (FTE)	$	167	$	176	$	139
Provision for loan losses	4		15		23
Noninterest income	42		35		42
Noninterest expenses	184		182		162
Net income (loss)	14		10		(2		)
Net credit-related charge-offs	12		16		23
Selected average balances:
Assets	6,173		6,250		5,558
Loans	5,462		5,571		5,106
Deposits	20,373		20,715		17,360

• Average loans declined $109 million, primarily due to decreases in Personal Banking and Small Business Banking.

• Average deposits decreased $342 million, primarily due to a decrease in Small Business Banking.

• Net interest income decreased $9 million, primarily due to a decrease in FTP funding credits, one less day in the quarter and lower loan yields, partially offset by lower deposit rates.

• The provision for loan losses decreased $11 million, reflecting declines in both Personal Banking and Small Business Banking.

• Noninterest income increased $7 million, primarily due to a fourth quarter 2011 charge of $5 million related to a derivative contract tied to the conversion rate of Visa Class B shares.

Wealth Management

(dollar amounts in millions)	1st Qtr '12		4th Qtr '11		1st Qtr '11
Net interest income (FTE)	$	47	$	46	$	44
Provision for loan losses	14		10		8
Noninterest income	65		55		64
Noninterest expenses	81		83		78
Net income	11		5		14
Net credit-related charge-offs	5		12		5
Selected average balances:
Assets	4,636		4,672		4,809
Loans	4,565		4,618		4,807
Deposits	3,611		3,400		2,800

• Average loans decreased $53 million.

• Average deposits increased $211 million, primarily reflecting an increase in Private Banking.

• Net interest income increased $1 million, primarily due to an increase in average deposit balances.

• The provision for loan losses increased $4 million, primarily due to an increase in the Florida market.

• Noninterest income increased $10 million, primarily due to increases in gains on the redemption of auction-rate securities, investment banking fees and fiduciary income.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 7

Geographic Market Segments

Comerica also provides market segment results for four primary geographic markets: Midwest, Western, Texas and Florida. In addition to the four primary geographic markets, Other Markets and International are also reported as market segments. The financial results below are based on methodologies in effect at March 31, 2012 and are presented on a fully taxable equivalent (FTE) basis. The accompanying narrative addresses first quarter 2012 results compared to fourth quarter 2011.

The following table presents net income (loss) by market segment.

(dollar amounts in millions)	1st Qtr '12					4th Qtr '11					1st Qtr '11
Midwest	$	68		30	%	$	53		25	%	$	53		29	%
Western	65			28		65			30		51			28
Texas	49			21		55			26		29			16
Florida	(1		)	—		(1		)	(1	)	(4		)	(2	)
Other Markets	38			16		32			15		38			22
International	12			5		12			5		12			7
	231			100	%	216			100	%	179			100	%
Finance & Other Businesses (a)	(101		)			(120		)			(76		)
Total	$	130				$	96				$	103

(a) Includes discontinued operations and items not directly associated with the geographic markets.

Midwest Market

(dollar amounts in millions)	1st Qtr '12		4th Qtr '11		1st Qtr '11
Net interest income (FTE)	$	198	$	202	$	203
Provision for loan losses	10		20		34
Noninterest income	98		85		100
Noninterest expenses	183		185		188
Net income	68		53		53
Net credit-related charge-offs	18		32		46
Selected average balances:
Assets	14,095		13,976		14,303
Loans	13,829		13,725		14,104
Deposits	19,415		19,076		18,230

• Average loans increased $104 million, primarily due to an increase in National Dealer Services.

• Average deposits increased $339 million, primarily due to increases in Personal Banking and the Financial Services Division.

• Net interest income decreased $4 million, primarily due one less day in the quarter, lower loan yields, and lower net FTP funding credits, partially offset by an increase in average loan balances and lower deposit rates.

• The provision for loan losses decreased $10 million, primarily reflecting decreases in Small Business Banking, Commercial Real Estate, Personal Banking and Global Corporate Banking, partially offset by an increase in Middle Market.

• Noninterest income increased $13 million, primarily due to fourth quarter 2011 charges of $5 million related to a derivative contract tied to the conversion rate of Visa Class B shares and increases in investment banking fees, commercial lending fees, service charges on deposit accounts and fiduciary income.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 8

Western Market

(dollar amounts in millions)	1st Qtr '12			4th Qtr '11			1st Qtr '11
Net interest income (FTE)	$	171		$	170		$	164
Provision for loan losses	(7		)	(12		)	11
Noninterest income	33			33			37
Noninterest expenses	107			109			109
Net income	65			65			51
Net credit-related charge-offs	11			5			26
Selected average balances:
Assets	12,623			12,266			12,590
Loans	12,383			12,026			12,383
Deposits	13,897			13,671			12,235

• Average loans increased $357 million, primarily due to increases in National Dealer Services and Technology and Life Sciences.

• Average deposits increased $226 million, primarily due to an increase in the Financial Services Division.

• Net interest income increased $1 million, primarily due to an increase in average loan balances, partially offset by lower loan yields and one less day in the quarter.

• The provision for loan losses increased $5 million, primarily reflecting increases in Commercial Real Estate, Small Business Banking and Middle Market, partially offset by a decrease in Technology and Life Sciences.

Texas Market

(dollar amounts in millions)	1st Qtr '12		4th Qtr '11		1st Qtr '11
Net interest income (FTE)	$	151	$	158	$	87
Provision for loan losses	14		8		4
Noninterest income	31		26		23
Noninterest expenses	92		89		61
Net income	49		55		29
Net credit-related charge-offs	7		4		8
Selected average balances:
Assets	10,082		9,712		7,031
Loans	9,295		8,952		6,824
Deposits	10,229		10,333		5,786

• Average loans increased $343 million, led by an increase in Energy, as well as increases in Middle Market and Global Corporate Banking, partially offset by a decrease in Commercial Real Estate.

• Average deposits decreased $104 million, primarily reflecting a decrease in Energy.

• Net interest income decreased $7 million, primarily due to lower loan yields, an increase in net FTP funding costs, and one less day in the quarter, partially offset by an increase in average loan balances and lower deposit rates.

• The provision for loan losses increased $6 million, primarily due to increases in Commercial Real Estate and Middle Market, partially offset by a decrease in Technology and Life Sciences.

• Noninterest income increased $5 million, primarily due to increases across numerous categories.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 9

Florida Market

(dollar amounts in millions)	1st Qtr '12			4th Qtr '11			1st Qtr '11
Net interest income (FTE)	$	10		$	11		$	11
Provision for loan losses	6			4			8
Noninterest income	4			4			4
Noninterest expenses	9			13			12
Net income	(1		)	(1		)	(4		)
Net credit-related charge-offs	2			7			8
Selected average balances:
Assets	1,416			1,435			1,553
Loans	1,418			1,457			1,580
Deposits	424			435			367

• Average loans decreased $39 million.

• The provision for loan losses increased $2 million, primarily due to an increase in Private Banking, partially offset by a decrease in Commercial Real Estate.

• Noninterest expenses decreased $4 million, due to decreases across numerous categories.

Conference Call and Webcast

Comerica will host a conference call to review first quarter 2012 financial results at 7 a.m. CT Tuesday, April 17, 2012. Interested parties may access the conference call by calling (800) 309-2262 or (706) 679-5261 (event ID No. 62064995). The call and supplemental financial information can also be accessed via Comerica's "Investor Relations" page at www.comerica.com. A telephone replay will be available approximately two hours following the conference call through April 30, 2012. The conference call replay can be accessed by calling (855) 859-2056 or (404) 537-3406 (event ID No. 62064995). A replay of the Webcast can also be accessed via Comerica's “Investor Relations” page at www.comerica.com.

Comerica Incorporated is a financial services company headquartered in Dallas, Texas, and strategically aligned by three major business segments: The Business Bank, The Retail Bank and Wealth Management. Comerica focuses on relationships and helping people and businesses be successful. In addition to Texas, Comerica Bank locations can be found in Arizona, California, Florida and Michigan, with select businesses operating in several other states, as well as in Canada and Mexico.

This press release contains both financial measures based on accounting principles generally accepted in the United States (GAAP) and non-GAAP based financial measures, which are used where management believes it to be helpful in understanding Comerica's results of operations or financial position. Where non-GAAP financial measures are used, the comparable GAAP financial measure, as well as a reconciliation to the comparable GAAP financial measure, can be found in this press release. These disclosures should not be viewed as a substitute for operating results determined in accordance with GAAP, nor are they necessarily comparable to non-GAAP performance measures that may be presented by other companies.

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COMERICA REPORTS FIRST QUARTER 2012 NET INCOME OF $130 MILLION - 10

Forward-looking Statements

Any statements in this news release that are not historical facts are forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. Words such as “anticipates,” “believes,” “contemplates,” “feels,” “expects,” “estimates,” “seeks,” “strives,” “plans,” “intends,” “outlook,” “forecast,” “position,” “target,” “mission,” “assume,” “achievable,” “potential,” “strategy,” “goal,” “aspiration,” “opportunity,” “initiative,” “outcome,” “continue,” “remain,” “maintain,” “on course,” “trend,” “objective,” “looks forward” and variations of such words and similar expressions, or future or conditional verbs such as “will,” “would,” “should,” “could,” “might,” “can,” “may” or similar expressions, as they relate to Comerica or its management, are intended to identify forward-looking statements. These forward-looking statements are predicated on the beliefs and assumptions of Comerica's management based on information known to Comerica's management as of the date of this news release and do not purport to speak as of any other date. Forward-looking statements may include descriptions of plans and objectives of Comerica's management for future or past operations, products or services, and forecasts of Comerica's revenue, earnings or other measures of economic performance, including statements of profitability, business segments and subsidiaries, estimates of credit trends and global stability. Such statements reflect the view of Comerica's management as of this date with respect to future events and are subject to risks and uncertainties. Should one or more of these risks materialize or should underlying beliefs or assumptions prove incorrect, Comerica's actual results could differ materially from those discussed. Factors that could cause or contribute to such differences are changes in general economic, political or industry conditions; changes in monetary and fiscal policies, including the interest rate policies of the Federal Reserve Board; volatility and disruptions in global capital and credit markets; changes in Comerica's credit rating; the interdependence of financial service companies; changes in regulation or oversight; unfavorable developments concerning credit quality; the acquisition of Sterling Bancshares, Inc., or any future acquisitions; the effects of more stringent capital or liquidity requirements; declines or other changes in the businesses or industries of Comerica's customers; the implementation of Comerica's strategies and business models, including the implementation of revenue enhancements and efficiency improvements; Comerica's ability to utilize technology to efficiently and effectively develop, market and deliver new products and services; operational difficulties, failure of technology infrastructure or information security incidents; changes in the financial markets, including fluctuations in interest rates and their impact on deposit pricing; competitive product and pricing pressures among financial institutions within Comerica's markets; changes in customer behavior; management's ability to maintain and expand customer relationships; management's ability to retain key officers and employees; the impact of legal and regulatory proceedings; the effectiveness of methods of reducing risk exposures; the effects of terrorist activities and other hostilities; the effects of catastrophic events including, but not limited to, hurricanes, tornadoes, earthquakes, fires, droughts and floods; changes in accounting standards and the critical nature of Comerica's accounting policies. Comerica cautions that the foregoing list of factors is not exclusive. For discussion of factors that may cause actual results to differ from expectations, please refer to our filings with the Securities and Exchange Commission. In particular, please refer to “Item 1A. Risk Factors” beginning on page 12 of Comerica's Annual Report on Form 10-K for the year ended December 31, 2011. Forward-looking statements speak only as of the date they are made. Comerica does not undertake to update forward-looking statements to reflect facts, circumstances, assumptions or events that occur after the date the forward-looking statements are made. For any forward-looking statements made in this news release or in any documents, Comerica claims the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995.

Media Contact:	Investor Contacts:
Wayne J. Mielke	Darlene P. Persons
(214) 462-4463	(214) 462-6831
	Brittany Butler
	(214) 462-6834

CONSOLIDATED FINANCIAL HIGHLIGHTS (unaudited)
Comerica Incorporated and Subsidiaries
	Three Months Ended
	March 31,			December 31,			March 31,
(in millions, except per share data)	2012			2011			2011
PER COMMON SHARE AND COMMON STOCK DATA
Diluted net income	$	0.66		$	0.48		$	0.57
Cash dividends declared	0.10			0.10			0.10
Common shareholders' equity (at period end)	35.44			34.80			33.25
Tangible common equity (at period end) (a)	32.06			31.42			32.37
Average diluted shares (in thousands)	196,021			196,729			178,425
KEY RATIOS
Return on average common shareholders' equity	7.50		%	5.51		%	7.08		%
Return on average assets	0.84			0.63			0.77
Tier 1 common capital ratio (a) (b)	10.33			10.37			10.35
Tier 1 risk-based capital ratio (b)	10.37			10.41			10.35
Total risk-based capital ratio (b)	14.11			14.25			14.80
Leverage ratio (b)	10.97			10.92			11.37
Tangible common equity ratio (a)	10.21			10.27			10.43
AVERAGE BALANCES
Commercial loans	$	24,736		$	23,515		$	21,496
Real estate construction loans:
Commercial Real Estate business line (c)	1,056			1,189			1,754
Other business lines (d)	397			430			425
Total real estate construction loans	1,453			1,619			2,179
Commercial mortgage loans:
Commercial Real Estate business line (c)	2,520			2,552			1,978
Other business lines (d)	7,682			7,836			7,812
Total commercial mortgage loans	10,202			10,388			9,790
Lease financing	897			919			987
International loans	1,205			1,128			1,219
Residential mortgage loans	1,519			1,591			1,599
Consumer loans	2,257			2,294			2,281
Total loans	42,269			41,454			39,551
Earning assets	56,186			55,676			49,347
Total assets	61,613			61,045			53,775
Noninterest-bearing deposits	19,637			19,176			15,459
Interest-bearing deposits	28,674			28,603			25,139
Total deposits	48,311			47,779			40,598
Common shareholders' equity	6,939			6,947			5,835
NET INTEREST INCOME
Net interest income (fully taxable equivalent basis)	$	444		$	445		$	396
Fully taxable equivalent adjustment	1			1			1
Net interest margin (fully taxable equivalent basis)	3.19		%	3.19		%	3.25		%
CREDIT QUALITY
Nonaccrual loans	$	830		$	860		$	996
Reduced-rate loans	26			27			34
Total nonperforming loans (e)	856			887			1,030
Foreclosed property	67			94			74
Total nonperforming assets (e)	923			981			1,104
Loans past due 90 days or more and still accruing	50			58			72
Gross loan charge-offs	62			85			123
Loan recoveries	17			25			22
Net loan charge-offs	45			60			101
Allowance for loan losses	704			726			849
Allowance for credit losses on lending-related commitments	25			26			32
Total allowance for credit losses	729			752			881
Allowance for loan losses as a percentage of total loans (f)	1.64		%	1.70		%	2.17		%
Net loan charge-offs as a percentage of average total loans (g)	0.43			0.57			1.03
Nonperforming assets as a percentage of total loans and foreclosed property (e)	2.14			2.29			2.81
Allowance for loan losses as a percentage of total nonperforming loans	82			82			82

(a) See Reconciliation of Non-GAAP Financial Measures.

(b) March 31, 2012 ratios are estimated.

(c) Primarily loans to real estate investors and developers.

(d) Primarily loans secured by owner-occupied real estate.

(e) Excludes loans acquired with credit-impairment.

(f) Reflects the impact of acquired loans, which were initially recorded at fair value with no related allowance for loan losses.

(g) Lending-related commitment charge-offs were zero in all periods presented.

11

CONSOLIDATED BALANCE SHEETS
Comerica Incorporated and Subsidiaries
	March 31,			December 31,			March 31,
(in millions, except share data)	2012			2011			2011
	(unaudited)						(unaudited)
ASSETS
Cash and due from banks	$	984		$	982		$	875
Federal funds sold	10			—			—
Interest-bearing deposits with banks	2,966			2,574			3,570
Other short-term investments	180			149			154
Investment securities available-for-sale	10,061			10,104			7,406
Commercial loans	25,640			24,996			21,360
Real estate construction loans	1,442			1,533			2,023
Commercial mortgage loans	10,079			10,264			9,697
Lease financing	872			905			958
International loans	1,256			1,170			1,326
Residential mortgage loans	1,485			1,526			1,550
Consumer loans	2,238			2,285			2,262
Total loans	43,012			42,679			39,176
Less allowance for loan losses	(704		)	(726		)	(849		)
Net loans	42,308			41,953			38,327
Premises and equipment	670			675			637
Accrued income and other assets	5,414			4,571			4,048
Total assets	$	62,593		$	61,008		$	55,017
LIABILITIES AND SHAREHOLDERS' EQUITY
Noninterest-bearing deposits	$	20,741		$	19,764		$	16,357
Money market and NOW deposits	20,502			20,311			17,888
Savings deposits	1,586			1,524			1,457
Customer certificates of deposit	6,145			5,808			5,672
Foreign office time deposits	332			348			499
Total interest-bearing deposits	28,565			27,991			25,516
Total deposits	49,306			47,755			41,873
Short-term borrowings	82			70			61
Accrued expenses and other liabilities	1,301			1,371			1,090
Medium- and long-term debt	4,919			4,944			6,116
Total liabilities	55,608			54,140			49,140
Common stock - $5 par value:
Authorized - 325,000,000 shares
Issued - 228,164,824 shares at 3/31/12 and 12/31/11
and 203,878,110 shares at 3/31/11	1,141			1,141			1,019
Capital surplus	2,154			2,170			1,464
Accumulated other comprehensive loss	(326		)	(356		)	(382		)
Retained earnings	5,630			5,546			5,317
Less cost of common stock in treasury - 31,032,920 shares at 3/31/12,
30,831,076 shares at 12/31/11 and 27,103,941 shares at 3/31/11	(1,614		)	(1,633		)	(1,541		)
Total shareholders' equity	6,985			6,868			5,877
Total liabilities and shareholders' equity	$	62,593		$	61,008		$	55,017

12

CONSOLIDATED STATEMENTS OF INCOME (unaudited)
Comerica Incorporated and Subsidiaries
	Three Months Ended
	March 31,
(in millions, except per share data)	2012		2011
INTEREST INCOME
Interest and fees on loans	$	411	$	375
Interest on investment securities	64		57
Interest on short-term investments	3		2
Total interest income	478		434
INTEREST EXPENSE
Interest on deposits	19		22
Interest on medium- and long-term debt	16		17
Total interest expense	35		39
Net interest income	443		395
Provision for loan losses	23		49
Net interest income after provision for loan losses	420		346
NONINTEREST INCOME
Service charges on deposit accounts	56		52
Fiduciary income	38		39
Commercial lending fees	25		21
Letter of credit fees	17		18
Card fees	11		15
Foreign exchange income	9		9
Bank-owned life insurance	10		8
Brokerage fees	6		6
Net securities gains	5		2
Other noninterest income	29		37
Total noninterest income	206		207
NONINTEREST EXPENSES
Salaries	201		188
Employee benefits	60		50
Total salaries and employee benefits	261		238
Net occupancy expense	41		40
Equipment expense	17		15
Outside processing fee expense	26		24
Software expense	23		23
FDIC insurance expense	10		15
Advertising expense	7		7
Other real estate expense	4		8
Other noninterest expenses	59		45
Total noninterest expenses	448		415
Income before income taxes	178		138
Provision for income taxes	48		35
NET INCOME	130		103
Less income allocated to participating securities	1		1
Net income attributable to common shares	$	129	$	102
Earnings per common share:
Basic	$	0.66	$	0.58
Diluted	0.66		0.57
Comprehensive income	160		110
Cash dividends declared on common stock	20		17
Cash dividends declared per common share	0.10		0.10

13

CONSOLIDATED QUARTERLY STATEMENTS OF INCOME (unaudited)
Comerica Incorporated and Subsidiaries
	First		Fourth			Third		Second		First		First Quarter 2012 Compared To:
	Quarter		Quarter			Quarter		Quarter		Quarter		Fourth Quarter 2011					First Quarter 2011
(in millions, except per share data)	2012		2011			2011		2011		2011		Amount			Percent		Amount			Percent
INTEREST INCOME
Interest and fees on loans	$	411	$	415		$	405	$	369	$	375	$	(4	)	(1	)%	$	36		10	%
Interest on investment securities	64		63			54		59		57		1			1		7			11
Interest on short-term investments	3		3			4		3		2		—			(6	)	1			34
Total interest income	478		481			463		431		434		(3		)	(1	)	44			10
INTEREST EXPENSE
Interest on deposits	19		21			24		23		22		(2		)	(10	)	(3		)	(17	)
Interest on medium- and long-term debt	16		16			16		17		17		—			1		(1		)	(1	)
Total interest expense	35		37			40		40		39		(2		)	(5	)	(4		)	(11	)
Net interest income	443		444			423		391		395		(1		)	—		48			12
Provision for loan losses	23		19			38		47		49		4			21		(26		)	(53	)
Net interest income after provision for loan losses	420		425			385		344		346		(5		)	(1	)	74			21
NONINTEREST INCOME
Service charges on deposit accounts	56		52			53		51		52		4			8		4			6
Fiduciary income	38		36			37		39		39		2			7		(1		)	(1	)
Commercial lending fees	25		23			22		21		21		2			5		4			20
Letter of credit fees	17		18			19		18		18		(1		)	(3	)	(1		)	(6	)
Card fees	11		11			17		15		15		—			(2	)	(4		)	(24	)
Foreign exchange income	9		10			11		10		9		(1		)	(11	)	—			6
Bank-owned life insurance	10		10			10		9		8		—			(2	)	2			15
Brokerage fees	6		5			5		6		6		1			15		—			(10	)
Net securities gains (losses)	5		(4		)	12		4		2		9			N/M		3			N/M
Other noninterest income	29		21			15		29		37		8			38		(8		)	(19	)
Total noninterest income	206		182			201		202		207		24			13		(1		)	—
NONINTEREST EXPENSES
Salaries	201		205			192		185		188		(4		)	(2	)	13			7
Employee benefits	60		52			53		50		50		8			14		10			18
Total salaries and employee benefits	261		257			245		235		238		4			1		23			10
Net occupancy expense	41		47			44		38		40		(6		)	(11	)	1			4
Equipment expense	17		17			17		17		15		—			(4	)	2			8
Outside processing fee expense	26		27			25		25		24		(1		)	(3	)	2			10
Software expense	23		23			22		20		23		—			1		—			1
Merger and restructuring charges	—		37			33		5		—		(37		)	(98	)	—			N/M
FDIC insurance expense	10		8			8		12		15		2			19		(5		)	(31	)
Advertising expense	7		7			7		7		7		—			2		—			—
Other real estate expense	4		3			5		6		8		1			21		(4		)	(57	)
Other noninterest expenses	59		52			54		44		45		7			13		14			31
Total noninterest expenses	448		478			460		409		415		(30		)	(6	)	33			8
Income before income taxes	178		129			126		137		138		49			38		40			29
Provision for income taxes	48		33			28		41		35		15			43		13			37
NET INCOME	130		96			98		96		103		34			36		27			26
Less income allocated to participating securities	1		1			1		1		1		—			72		—			33
Net income attributable to common shares	$	129	$	95		$	97	$	95	$	102	$	34		36	%	$	27		26	%
Earnings per common share:
Basic	$	0.66	$	0.48		$	0.51	$	0.54	$	0.58	$	0.18		38	%	$	0.08		14	%
Diluted	0.66		0.48			0.51		0.53		0.57		0.18			38		0.09			16
Comprehensive income (loss)	160		(30		)	176		170		110		190			N/M		50			46
Cash dividends declared on common stock	20		20			20		18		17		—			(1	)	3			11
Cash dividends declared per common share	0.10		0.10			0.10		0.10		0.10		—			—		—			—

N/M - Not Meaningful

14

ANALYSIS OF THE ALLOWANCE FOR LOAN LOSSES (unaudited)
Comerica Incorporated and Subsidiaries
	2012			2011
(in millions)	1st Qtr			4th Qtr			3rd Qtr			2nd Qtr			1st Qtr
Balance at beginning of period	$	726		$	767		$	806		$	849		$	901
Loan charge-offs:
Commercial	25			28			33			66			65
Real estate construction:
Commercial Real Estate business line (a)	2			4			11			12			8
Other business lines (b)	—			1			—			—			1
Total real estate construction	2			5			11			12			9
Commercial mortgage:
Commercial Real Estate business line (a)	13			17			12			8			9
Other business lines (b)	13			24			21			23			25
Total commercial mortgage	26			41			33			31			34
International	2			2			—			—			5
Residential mortgage	2			2			4			7			2
Consumer	5			7			9			9			8
Total loan charge-offs	62			85			90			125			123
Recoveries on loans previously charged-off:
Commercial	9			11			5			13			4
Real estate construction	1			4			3			5			2
Commercial mortgage	3			9			3			5			9
Lease financing	—			—			—			6			5
International	1			—			—			4			1
Residential mortgage	1			—			1			1			—
Consumer	2			1			1			1			1
Total recoveries	17			25			13			35			22
Net loan charge-offs	45			60			77			90			101
Provision for loan losses	23			19			38			47			49
Balance at end of period	$	704		$	726		$	767		$	806		$	849
Allowance for loan losses as a percentage of total loans (c)	1.64		%	1.70		%	1.86		%	2.06		%	2.17		%
Net loan charge-offs as a percentage of average total loans	0.43			0.57			0.77			0.92			1.03

(a) Primarily charge-offs of loans to real estate investors and developers.

(b) Primarily charge-offs of loans secured by owner-occupied real estate.

(c) Reflects the impact of acquired loans, which were initially recorded at fair value with no related allowance for loan losses.

ANALYSIS OF THE ALLOWANCE FOR CREDIT LOSSES ON LENDING-RELATED COMMITMENTS (unaudited)
Comerica Incorporated and Subsidiaries
	2012			2011
(in millions)	1st Qtr			4th Qtr			3rd Qtr			2nd Qtr			1st Qtr
Balance at beginning of period	$	26		$	27		$	30		$	32		$	35
Add: Provision for credit losses on lending-related commitments	(1		)	(1		)	(3		)	(2		)	(3		)
Balance at end of period	$	25		$	26		$	27		$	30		$	32
Unfunded lending-related commitments sold	$	—		$	—		$	—		$	3		$	2

15

NONPERFORMING ASSETS (unaudited)
Comerica Incorporated and Subsidiaries
	2012			2011
(in millions)	1st Qtr			4th Qtr			3rd Qtr			2nd Qtr			1st Qtr
SUMMARY OF NONPERFORMING ASSETS AND PAST DUE LOANS
Nonaccrual loans:
Business loans:
Commercial	$	205		$	237		$	258		$	261		$	226
Real estate construction:
Commercial Real Estate business line (a)	77			93			109			137			195
Other business lines (b)	8			8			3			2			3
Total real estate construction	85			101			112			139			198
Commercial mortgage:
Commercial Real Estate business line (a)	174			159			198			186			197
Other business lines (b)	275			268			275			269			293
Total commercial mortgage	449			427			473			455			490
Lease financing	4			5			5			6			7
International	4			8			7			7			4
Total nonaccrual business loans	747			778			855			868			925
Retail loans:
Residential mortgage	69			71			65			60			58
Consumer:
Home equity	9			5			4			4			6
Other consumer	5			6			5			9			7
Total consumer	14			11			9			13			13
Total nonaccrual retail loans	83			82			74			73			71
Total nonaccrual loans	830			860			929			941			996
Reduced-rate loans	26			27			29			33			34
Total nonperforming loans (c)	856			887			958			974			1,030
Foreclosed property	67			94			87			70			74
Total nonperforming assets (c)	$	923		$	981		$	1,045		$	1,044		$	1,104
Nonperforming loans as a percentage of total loans	1.99		%	2.08		%	2.32		%	2.49		%	2.63		%
Nonperforming assets as a percentage of total loans  and foreclosed property	2.14			2.29			2.53			2.66			2.81
Allowance for loan losses as a percentage of total nonperforming loans	82			82			80			83			82
Loans past due 90 days or more and still accruing	$	50		$	58		$	81		$	64		$	72
ANALYSIS OF NONACCRUAL LOANS
Nonaccrual loans at beginning of period	$	860		$	929		$	941		$	996		$	1,080
Loans transferred to nonaccrual (d)	69			99			130			150			149
Nonaccrual business loan gross charge-offs (e)	(55		)	(76		)	(76		)	(109		)	(111		)
Loans transferred to accrual status (d)	—			—			(15		)	—			(4		)
Nonaccrual business loans sold (f)	(7		)	(19		)	(15		)	(16		)	(60		)
Payments/Other (g)	(37		)	(73		)	(36		)	(80		)	(58		)
Nonaccrual loans at end of period	$	830		$	860		$	929		$	941		$	996
(a) Primarily loans to real estate investors and developers.
(b) Primarily loans secured by owner-occupied real estate.
(c) Excludes loans acquired with credit impairment.
(d) Based on an analysis of nonaccrual loans with book balances greater than $2 million.
(e) Analysis of gross loan charge-offs:
Nonaccrual business loans	$	55		$	76		$	76		$	109		$	111
Performing watch list loans	—			—			1			—			2
Consumer and residential mortgage loans	7			9			13			16			10
Total gross loan charge-offs	$	62		$	85		$	90		$	125		$	123
(f) Analysis of loans sold:
Nonaccrual business loans	$	7		$	19		$	15		$	16		$	60
Performing watch list loans	11			—			16			6			35
Total loans sold	$	18		$	19		$	31		$	22		$	95
(g) Includes net changes related to nonaccrual loans with balances less than $2 million, payments on nonaccrual loans with book balances greater than $2 million and transfers of nonaccrual loans to foreclosed property. Excludes business loan gross charge-offs and business nonaccrual loans sold.

16

ANALYSIS OF NET INTEREST INCOME (FTE) (unaudited)
Comerica Incorporated and Subsidiaries
	Three Months Ended
	March 31, 2012							December 31, 2011							March 31, 2011
	Average					Average		Average					Average		Average					Average
(dollar amounts in millions)	Balance			Interest		Rate		Balance			Interest		Rate		Balance			Interest		Rate
Commercial loans	$	24,736		$	219	3.56	%	$	23,515		$	216	3.64	%	$	21,496		$	201	3.76	%
Real estate construction loans	1,453			17		4.58		1,619			21		5.26		2,179			19		3.51
Commercial mortgage loans	10,202			119		4.73		10,388			119		4.54		9,790			95		3.95
Lease financing	897			8		3.41		919			8		3.44		987			9		3.62
International loans	1,205			11		3.76		1,128			10		3.63		1,219			12		3.87
Residential mortgage loans	1,519			18		4.77		1,591			20		5.06		1,599			21		5.24
Consumer loans	2,257			20		3.49		2,294			21		3.58		2,281			19		3.42
Total loans (a)	42,269			412		3.92		41,454			415		3.98		39,551			376		3.85
Auction-rate securities available-for-sale	352			1		0.63		426			1		0.64		554			1		0.88
Other investment securities available-for-sale	9,537			63		2.73		9,355			62		2.74		6,757			56		3.37
Total investment securities available-for-sale	9,889			64		2.65		9,781			63		2.64		7,311			57		3.17
Federal funds sold	9			—		0.29		15			—		0.32		3			—		0.32
Interest-bearing deposits with banks (b)	3,884			2		0.26		4,293			3		0.24		2,354			1		0.26
Other short-term investments	135			1		1.97		133			1		2.26		128			1		2.68
Total earning assets	56,186			479		3.44		55,676			482		3.45		49,347			435		3.57
Cash and due from banks	999							959							884
Allowance for loan losses	(737		)					(773		)					(908		)
Accrued income and other assets	5,165							5,183							4,452
Total assets	$	61,613						$	61,045						$	53,775
Money market and NOW deposits	$	20,795		10		0.19		$	20,716		12		0.21		$	17,797		12		0.26
Savings deposits	1,543			—		0.08		1,652			—		0.12		1,421			—		0.09
Customer certificates of deposit	5,978			8		0.57		5,872			9		0.60		5,509			10		0.76
Foreign office and other time deposits	358			1		0.57		363			—		0.40		412			—		0.49
Total interest-bearing deposits	28,674			19		0.26		28,603			21		0.29		25,139			22		0.37
Short-term borrowings	78			—		0.11		142			—		0.07		94			—		0.31
Medium- and long-term debt	4,940			16		1.34		4,976			16		1.30		6,128			17		1.10
Total interest-bearing sources	33,692			35		0.42		33,721			37		0.44		31,361			39		0.51
Noninterest-bearing deposits	19,637							19,176							15,459
Accrued expenses and other liabilities	1,345							1,201							1,120
Total shareholders' equity	6,939							6,947							5,835
Total liabilities and shareholders' equity	$	61,613						$	61,045						$	53,775
Net interest income/rate spread (FTE)				$	444	3.02					$	445	3.01					$	396	3.06
FTE adjustment				$	1						$	1						$	1
Impact of net noninterest-bearing sources of funds						0.17							0.18							0.19
Net interest margin (as a percentage of average earning assets) (FTE) (a) (b)						3.19	%						3.19	%						3.25	%

(a) Accretion of the purchase discount on the acquired loan portfolio of $25 million in the first quarter of 2012 and $26 million in the fourth quarter of 2011 increased the net interest margin by 18 basis points in the first quarter of 2012 and by 19 basis points in the fourth quarter of 2011.

(b) Excess liquidity, represented by average balances deposited with the Federal Reserve Bank, reduced the net interest margin by 21 basis points in the first quarter of 2012, and by 24 basis points and 14 basis points in the fourth and first quarters of 2011, respectively.

17

CONSOLIDATED STATISTICAL DATA (unaudited)
Comerica Incorporated and Subsidiaries
	March 31,				December 31,				September 30,				June 30,				March 31,
(in millions, except per share data)	2012				2011				2011				2011				2011
Commercial loans:
Floor plan	$	2,152			$	1,822			$	1,209			$	1,478			$	1,893
Other	23,488				23,174				21,904				20,574				19,467
Total commercial loans	25,640				24,996				23,113				22,052				21,360
Real estate construction loans:
Commercial Real Estate business line (a)	1,055				1,103				1,226				1,343				1,606
Other business lines (b)	387				430				422				385				417
Total real estate construction loans	1,442				1,533				1,648				1,728				2,023
Commercial mortgage loans:
Commercial Real Estate business line (a)	2,501				2,507				2,602				1,930				1,918
Other business lines (b)	7,578				7,757				7,937				7,649				7,779
Total commercial mortgage loans	10,079				10,264				10,539				9,579				9,697
Lease financing	872				905				927				949				958
International loans	1,256				1,170				1,046				1,162				1,326
Residential mortgage loans	1,485				1,526				1,643				1,491				1,550
Consumer loans:
Home equity	1,612				1,655				1,683				1,622				1,661
Other consumer	626				630				626				610				601
Total consumer loans	2,238				2,285				2,309				2,232				2,262
Total loans	$	43,012			$	42,679			$	41,225			$	39,193			$	39,176
Goodwill	$	635			$	635			$	635			$	150			$	150
Core deposit intangible	27				29				32				—				—
Loan servicing rights	3				3				3				4				4
Tier 1 common capital ratio (c) (d)	10.33		%		10.37		%		10.57		%	%	10.53		%	%	10.35		%
Tier 1 risk-based capital ratio (d)	10.37				10.41				10.65				10.53				10.35
Total risk-based capital ratio (d)	14.11				14.25				14.84				14.80				14.80
Leverage ratio (d)	10.97				10.92				11.41				11.40				11.37
Tangible common equity ratio (c)	10.21				10.27				10.43				10.90				10.43
Common shareholders' equity per share of common stock	$	35.44			$	34.80			$	34.94			$	34.15			$	33.25
Tangible common equity per share of common stock (c)	32.06				31.42				31.57				33.28				32.37
Market value per share for the quarter:
High	34.00				27.37				35.79				39.00				43.53
Low	26.25				21.53				21.48				33.08				36.20
Close	32.36				25.80				22.97				34.57				36.72
Quarterly ratios:
Return on average common shareholders' equity	7.50		%	%	5.51		%	%	5.91		%	%	6.41		%	%	7.08		%
Return on average assets	0.84				0.63				0.67				0.70				0.77
Efficiency ratio	69.50				75.78				75.11				69.33				69.05
Number of banking centers	495				494				502				446				445
Number of employees - full time equivalent	9,195				9,397				9,701				8,915				8,955

(a) Primarily loans to real estate investors and developers.

(b) Primarily loans secured by owner-occupied real estate.

(c) See Reconciliation of Non-GAAP Financial Measures.

(d) March 31, 2012 ratios are estimated.

18

PARENT COMPANY ONLY BALANCE SHEETS (unaudited)
Comerica Incorporated
											March 31,			December 31,			March 31,
(in millions, except share data)											2012			2011			2011
ASSETS
Cash and due from subsidiary bank											$	6		$	7		7
Short-term investments with subsidiary bank											388			411			334
Other short-term investments											94			90			90
Investment in subsidiaries, principally banks											7,120			7,011			6,033
Premises and equipment											5			4			3
Other assets											183			177			174
Total assets											$	7,796		$	7,700		$	6,641
LIABILITIES AND SHAREHOLDERS' EQUITY
Medium- and long-term debt											$	660		$	666		$	631
Other liabilities											151			166			133
Total liabilities											811			832			764
Common stock - $5 par value:
Authorized - 325,000,000 shares
Issued - 228,164,824 shares at 3/31/12 and 12/31/11 and 203,878,110 shares at 3/31/11											1,141			1,141			1,019
Capital surplus											2,154			2,170			1,464
Accumulated other comprehensive loss											(326		)	(356		)	(382		)
Retained earnings											5,630			5,546			5,317
Less cost of common stock in treasury - 31,032,920 shares at 3/31/12, 30,831,076 shares at 12/31/11, and 27,103,941 shares at 3/31/11											(1,614		)	(1,633		)	(1,541		)
Total shareholders' equity											6,985			6,868			5,877
Total liabilities and shareholders' equity											$	7,796		$	7,700		$	6,641
CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY (unaudited)
Comerica Incorporated and Subsidiaries
								Accumulated
	Common Stock							Other									Total
	Shares				Capital			Comprehensive			Retained			Treasury			Shareholders'
(in millions, except per share data)	Outstanding		Amount		Surplus			Loss			Earnings			Stock			Equity
BALANCE AT DECEMBER 31, 2010	176.5		$	1,019	$	1,481		$	(389	)	$	5,247		$	(1,565	)	$	5,793
Net income	—		—		—			—			103			—			103
Other comprehensive income, net of tax	—		—		—			7			—			—			7
Cash dividends declared on common stock ($0.10 per share)	—		—		—			—			(17		)	—			(17		)
Purchase of common stock	(0.5	)	—		—			—			—			(21		)	(21		)
Net issuance of common stock under employee stock plans	0.8		—		(30		)	—			(16		)	45			(1		)
Share-based compensation	—		—		13			—			—			—			13
BALANCE AT MARCH 31, 2011	176.8		$	1,019	$	1,464		$	(382	)	$	5,317		$	(1,541	)	$	5,877
BALANCE AT DECEMBER 31, 2011	197.3		$	1,141	$	2,170		$	(356	)	$	5,546		$	(1,633	)	$	6,868
Net income	—		—		—			—			130			—			130
Other comprehensive income, net of tax	—		—		—			30			—			—			30
Cash dividends declared on common stock ($0.10 per share)	—		—		—			—			(20		)	—			(20		)
Purchase of common stock	(1.2	)	—		—			—			—			(36		)	(36		)
Net issuance of common stock under employee stock plans	1.1		—		(32		)	—			(26		)	58			—
Share-based compensation	—		—		13			—			—			—			13
Other	(0.1	)	—		3			—			—			(3		)	—
BALANCE AT MARCH 31, 2012	197.1		$	1,141	$	2,154		$	(326	)	$	5,630		$	(1,614	)	$	6,985

19

BUSINESS SEGMENT FINANCIAL RESULTS (unaudited)
Comerica Incorporated and Subsidiaries
(dollar amounts in millions)	Business			Retail			Wealth
Three Months Ended March 31, 2012	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	379		$	167		$	47		$	(156	)	$	7		$	444
Provision for loan losses	1			4			14			—			4			23
Noninterest income	81			42			65			13			5			206
Noninterest expenses	159			184			81			3			21			448
Provision (benefit) for income taxes (FTE)	94			7			6			(54		)	(4		)	49
Net income (loss)	$	206		$	14		$	11		$	(92	)	$	(9	)	$	130
Net credit-related charge-offs	$	28		$	12		$	5		—			—			$	45
Selected average balances:
Assets	$	33,184		$	6,173		$	4,636		$	12,095		$	5,525		$	61,613
Loans	32,240			5,462			4,565			2			—			42,269
Deposits	23,997			20,373			3,611			161			169			48,311
Statistical data:
Return on average assets (a)	2.49		%	0.27		%	0.97		%	N/M			N/M			0.84		%
Efficiency ratio	34.74			87.73			75.23			N/M			N/M			69.50
	Business			Retail			Wealth
Three Months Ended December 31, 2011	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	383		$	176		$	46		$	(169	)	$	9		$	445
Provision for loan losses	(4		)	15			10			—			(2		)	19
Noninterest income	73			35			55			18			1			182
Noninterest expenses	161			182			83			3			49			478
Provision (benefit) for income taxes (FTE)	98			4			3			(60		)	(11		)	34
Net income (loss)	$	201		$	10		$	5		$	(94	)	$	(26	)	$	96
Net credit-related charge-offs	$	32		$	16		$	12		—			—			$	60
Selected average balances:
Assets	$	32,151		$	6,250		$	4,672		$	11,959		$	6,013		$	61,045
Loans	31,257			5,571			4,618			3			5			41,454
Deposits	23,296			20,715			3,400			200			168			47,779
Statistical data:
Return on average assets (a)	2.50		%	0.18		%	0.45		%	N/M			N/M			0.63		%
Efficiency ratio	35.55			84.31			82.12			N/M			N/M			75.78
	Business			Retail			Wealth
Three Months Ended March 31, 2011	Bank			Bank			Management			Finance			Other			Total
Earnings summary:
Net interest income (expense) (FTE)	$	341		$	139		$	44		$	(135	)	7			$	396
Provision for loan losses	18			23			8			—			—			49
Noninterest income	77			42			64			18			6			207
Noninterest expenses	160			162			78			2			13			415
Provision (benefit) for income taxes (FTE)	73			(2		)	8			(44		)	1			36
Net income (loss)	$	167		$	(2	)	$	14		$	(75	)	$	(1	)	$	103
Net credit-related charge-offs	$	73		$	23		$	5		—			—			$	101
Selected average balances:
Assets	$	30,092		$	5,558		$	4,809		$	9,370		$	3,946		$	53,775
Loans	29,609			5,106			4,807			22			7			39,551
Deposits	20,084			17,360			2,800			249			105			40,598
Statistical data:
Return on average assets (a)	2.22		%	(0.05		)%	1.14		%	N/M			N/M			0.77		%
Efficiency ratio	38.14			89.19			74.38			N/M			N/M			69.05

(a) Return on average assets is calculated based on the greater of average assets or average liabilities and attributed equity.

FTE - Fully Taxable Equivalent

N/M - Not Meaningful

20

MARKET SEGMENT FINANCIAL RESULTS (unaudited)
Comerica Incorporated and Subsidiaries
																			Finance
(dollar amounts in millions)													Other						& Other
Three Months Ended March 31, 2012	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	198		$	171		$	151		$	10		$	45		$	18		$	(149	)	$	444
Provision for loan losses	10			(7		)	14			6			(3		)	(1		)	4			23
Noninterest income	98			33			31			4			14			8			18			206
Noninterest expenses	183			107			92			9			24			9			24			448
Provision (benefit) for income taxes (FTE)	35			39			27			—			—			6			(58		)	49
Net income (loss)	$	68		$	65		$	49		$	(1	)	$	38		$	12		$	(101	)	$	130
Net credit-related charge-offs	$	18		$	11		$	7		$	2		$	6		$	1		—			$	45
Selected average balances:
Assets	$	14,095		$	12,623		$	10,082		$	1,416		$	4,021		$	1,756		$	17,620		$	61,613
Loans	13,829			12,383			9,295			1,418			3,693			1,649			2			42,269
Deposits	19,415			13,897			10,229			424			2,628			1,388			330			48,311
Statistical data:
Return on average assets (a)	1.33		%	1.75		%	1.72		%	(0.21		)%	3.77		%	2.73		%	N/M			0.84		%
Efficiency ratio	61.78			52.50			50.33			68.94			44.62			33.02			N/M			69.50
																			Finance
													Other						& Other
Three Months Ended December 31, 2011	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	202		$	170		$	158		$	11		$	46		$	18		$	(160	)	$	445
Provision for loan losses	20			(12		)	8			4			—			1			(2		)	19
Noninterest income	85			33			26			4			7			8			19			182
Noninterest expenses	185			109			89			13			23			7			52			478
Provision (benefit) for income taxes (FTE)	29			41			32			(1		)	(2		)	6			(71		)	34
Net income (loss)	$	53		$	65		$	55		$	(1	)	$	32		$	12		$	(120	)	$	96
Net credit-related charge-offs	$	32		$	5		$	4		$	7		$	10		2			—			$	60
Selected average balances:
Assets	$	13,976		$	12,266		$	9,712		$	1,435		$	4,016		$	1,668		$	17,972		$	61,045
Loans	13,725			12,026			8,952			1,457			3,718			1,568			8			41,454
Deposits	19,076			13,671			10,333			435			2,414			1,482			368			47,779
Statistical data:
Return on average assets (a)	1.07		%	1.77		%	1.92		%	(0.37		)%	3.15		%	2.78		%	N/M			0.63		%
Efficiency ratio	63.47			53.94			48.13			92.29			44.64			28.20			N/M			75.78
																			Finance
													Other						& Other
Three Months Ended March 31, 2011	Midwest			Western			Texas			Florida			Markets			International			Businesses			Total
Earnings summary:
Net interest income (expense) (FTE)	$	203		$	164		$	87		$	11		$	41		$	18		$	(128	)	$	396
Provision for loan losses	34			11			4			8			(7		)	(1		)	—			49
Noninterest income	100			37			23			4			11			8			24			207
Noninterest expenses	188			109			61			12			21			9			15			415
Provision (benefit) for income taxes (FTE)	28			30			16			(1		)	—			6			(43		)	36
Net income (loss)	$	53		$	51		$	29		$	(4	)	$	38		$	12		$	(76	)	$	103
Net credit-related charge-offs	$	46		$	26		$	8		$	8		$	9		4			—			$	101
Selected average balances:
Assets	$	14,303		$	12,590		$	7,031		$	1,553		$	3,247		$	1,735		$	13,316		$	53,775
Loans	14,104			12,383			6,824			1,580			2,960			1,671			29			39,551
Deposits	18,230			12,235			5,786			367			2,298			1,328			354			40,598
Statistical data:
Return on average assets (a)	1.07		%	1.54		%	1.65		%	(0.93		)%	4.74		%	2.79		%	N/M			0.77		%
Efficiency ratio	62.11			54.34			55.39			80.08			41.67			34.62			N/M			69.05

(a) Return on average assets is calculated based on the greater of average assets or average liabilities and attributed equity.

FTE - Fully Taxable Equivalent

N/M - Not Meaningful

21

RECONCILIATION OF NON-GAAP FINANCIAL MEASURES (unaudited)
Comerica Incorporated and Subsidiaries
	March 31,			December 31,			September 30,			June 30,			March 31,
(dollar amounts in millions)	2012			2011			2011			2011			2011
Tier 1 Common Capital Ratio:
Tier 1 capital (a) (b)	$	6,672		$	6,582		$	6,560		$	6,193		$	6,107
Less:
Trust preferred securities	25			25			49			—			—
Tier 1 common capital (b)	$	6,647		$	6,557		$	6,511		$	6,193		$	6,107
Risk-weighted assets (a) (b)	$	64,362		$	63,244		$	61,593		$	58,795		$	58,998
Tier 1 risk-based capital ratio (b)	10.37		%	10.41		%	10.65		%	10.53		%	10.35		%
Tier 1 common capital ratio (b)	10.33			10.37			10.57			10.53			10.35
Tangible Common Equity Ratio:
Common shareholders' equity	$	6,985		$	6,868		$	6,951		$	6,038		$	5,877
Less:
Goodwill	635			635			635			150			150
Other intangible assets	30			32			35			4			5
Tangible common equity	$	6,320		$	6,201		$	6,281		$	5,884		$	5,722
Total assets	$	62,593		$	61,008		$	60,888		$	54,141		$	55,017
Less:
Goodwill	635			635			635			150			150
Other intangible assets	30			32			35			4			5
Tangible assets	$	61,928		$	60,341		$	60,218		$	53,987		$	54,862
Common equity ratio	11.16		%	11.26		%	11.42		%	11.15		%	10.68		%
Tangible common equity ratio	10.21			10.27			10.43			10.90			10.43
Tangible Common Equity per Share of Common Stock:
Common shareholders' equity	$	6,985		$	6,868		$	6,951		$	6,038		$	5,877
Tangible common equity	6,320			6,201			6,281			5,884			5,722
Shares of common stock outstanding (in millions)	197			197			199			177			177
Common shareholders' equity per share of common stock	$	35.44		$	34.80		$	34.94		$	34.15		$	33.25
Tangible common equity per share of common stock	32.06			31.42			31.57			33.28			32.37

(a) Tier 1 capital and risk-weighted assets as defined by regulation.

(b) March 31, 2012 Tier 1 capital and risk-weighted assets are estimated.

The Tier 1 common capital ratio removes preferred stock and qualifying trust preferred securities from Tier 1 capital as defined by and calculated in conformity with bank regulations. The tangible common equity removes preferred stock and the effect of intangible assets from capital and the effect of intangible assets from total assets and tangible common equity per share of common stock removes the effect of intangible assets from common shareholders equity per share of common stock. Comerica believes these measurements are meaningful measures of capital adequacy used by investors, regulators, management and others to evaluate the adequacy of common equity and to compare against other companies in the industry.

22