POWER OF ATTORNEY



David E. Duprey





Know all by these presents, that the undersigned hereby constitutes and

 appoints each of Jon W. Bilstrom, Nicole V. Gersch, and Robert W.

Spencer, Jr., signing singly, the undersigned's true and lawful

attorney-in-fact to:



(1) execute for and on behalf of the undersigned, in the

undersigned's capacity as an officer and/or director of Comerica

Incorporated (the "Company"), Forms 3, 4 and 5 in accordance with

Section 16(a) of the Securities Exchange Act of 1934 and the rules

thereunder;



(2) execute for and on behalf of the undersigned, in the

undersigned's capacity as an officer and/or director of the Company,

documents necessary to facilitate the filing of Forms 3, 4 and 5;



(3) do and perform any and all acts for and on behalf of the

undersigned which may be necessary or desirable to complete and execute

any such Form 3, 4 or 5 and timely file such form with the United

States Securities and Exchange Commission and any stock exchange or

similar authority; and



(4) take any other action of any type whatsoever in connection with

the foregoing which, in the opinion of such attorney-in-fact, may be of

benefit to, in the best interest of, or legally required by, the

undersigned, it being understood that the documents executed by such

attorney-in-fact on behalf of the undersigned pursuant to this Power of

Attorney shall be in such form and shall contain such terms and

conditions as such attorney-in-fact may approve in such

attorney-in-fact's discretion.



The undersigned hereby grants to each such attorney-in-fact full power

 and authority to do and perform any and every act and thing whatsoever

 requisite, necessary, or proper to be done in the exercise of any of

the rights and powers herein granted, as fully to all intents and all

purposes as the undersigned might or could do if personally present,

with full power of substitution or revocation, hereby ratifying and

confirming all that such attorney-in-fact, or such attorney-in-fact's

 substitute or substitutes, shall lawfully do or cause to be done by

virtue of this power of attorney and the rights and powers herein

granted.  The undersigned acknowledges that the foregoing

attorneys-in-fact, in serving in such capacity at the request of the

 undersigned, are not assuming, nor is the Company assuming, any of the

 undersigned's responsibilities to comply with Section 16 of the

Securities Exchange Act of 1934.





The termination of any attorney-in-fact's employment by the Company,

however caused, shall operate as a termination of his or her powers

and authorities hereunder, but shall not affect the powers and

authorities herein granted to any other party.



This Power of Attorney shall remain in full force and effect until

the undersigned is no longer required to file Forms 3, 4 and 5 with

respect to the undersigned's holdings of and transactions in securities

 issued by the Company, unless earlier revoked by the undersigned in

a signed writing delivered to the foregoing attorneys-in-fact at the

then current mailing address of the Corporate Legal Department of

Comerica Incorporated.



All Powers of Attorney previously granted in connection with the

foregoing matters hereby are canceled and revoked.



IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney

 to be executed and made effective as of this 1st day of April,

2006.









/s/ David E. Duprey

 David E. Duprey