UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Notice of Effectiveness
Effectiveness Date:	May 8, 2009 1:15 P.M.

Form:

N-14

CIK: 0000277751 Company Name: JANUS INVESTMENT FUND File Number: 333-158030 SERIES/CLASSES (CONTRACTS) MERGERS CIK Series ID Class/Contract Name Acquiring: 0000277751 JANUS INVESTMENT FUND S000010474 Janus Orion Fund C000077678 Class A Target: 0001110822 JANUS ADVISER SERIES S000010561 Janus Adviser Orion Fund C000029141 Class A CIK Series ID Class/Contract Name Acquiring: 0000277751 JANUS INVESTMENT FUND S000010474 Janus Orion Fund C000077679 Class C Target: 0001110822 JANUS ADVISER SERIES S000010561 Janus Adviser Orion Fund C000029142 Class C CIK Series ID Class/Contract Name Acquiring: 0000277751 JANUS INVESTMENT FUND S000010474 Janus Orion Fund C000077680 Class I Target: 0001110822 JANUS ADVISER SERIES S000010561 Janus Adviser Orion Fund C000029143 Class I CIK Series ID Class/Contract Name Acquiring: 0000277751 JANUS INVESTMENT FUND S000010474 Janus Orion Fund C000077681 Class R Target: 0001110822 JANUS ADVISER SERIES S000010561 Janus Adviser Orion Fund C000029144 Class R CIK Series ID Class/Contract Name Acquiring: 0000277751 JANUS INVESTMENT FUND S000010474 Janus Orion Fund C000077682 Class S Target: 0001110822 JANUS ADVISER SERIES S000010561 Janus Adviser Orion Fund C000029145 Class S