-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 JqdumpYjR86gdy7vQhCLSyYMkNx7yCrtQZY9Rqv4qNCWAG909Ml6gQbZrC5NRdEJ
 rh4GaSpV+7Dmy9tiPaQ6/A==

<SEC-DOCUMENT>9999999995-09-001357.txt : 20090511
<SEC-HEADER>9999999995-09-001357.hdr.sgml : 20090511
<ACCEPTANCE-DATETIME>20090511001517
ACCESSION NUMBER:		9999999995-09-001357
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20090508
DATE AS OF CHANGE:		20090511
EFFECTIVENESS DATE:		20090508

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			JANUS INVESTMENT FUND
		CENTRAL INDEX KEY:			0000277751
		IRS NUMBER:				840592523
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-158030
		FILM NUMBER:		09812534

	BUSINESS ADDRESS:	
		STREET 1:		151 DETROIT STREET
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206
		BUSINESS PHONE:		3033333863

	MAIL ADDRESS:	
		STREET 1:		151 DETROIT STREET
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS FUND /MD/
		DATE OF NAME CHANGE:	19870701
<SERIES-AND-CLASSES-CONTRACTS-DATA>
<MERGER-SERIES-AND-CLASSES-CONTRACTS>
<MERGER>
<ACQUIRING-DATA>
CENTRAL INDEX KEY:			0000277751
<SERIES>
<SERIES-ID>S000010474
<SERIES-NAME>Janus Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000077678
<CLASS-CONTRACT-NAME>Class A
</CLASS-CONTRACT>
</SERIES>
</ACQUIRING-DATA>
<TARGET-DATA>
CENTRAL INDEX KEY:			0001110822
<SERIES>
<SERIES-ID>S000010561
<SERIES-NAME>Janus Adviser Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000029141
<CLASS-CONTRACT-NAME>Class A
<CLASS-CONTRACT-TICKER-SYMBOL>JORAX
</CLASS-CONTRACT>
</SERIES>
</TARGET-DATA>
</MERGER>
<MERGER>
<ACQUIRING-DATA>
CENTRAL INDEX KEY:			0000277751
<SERIES>
<SERIES-ID>S000010474
<SERIES-NAME>Janus Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000077679
<CLASS-CONTRACT-NAME>Class C
</CLASS-CONTRACT>
</SERIES>
</ACQUIRING-DATA>
<TARGET-DATA>
CENTRAL INDEX KEY:			0001110822
<SERIES>
<SERIES-ID>S000010561
<SERIES-NAME>Janus Adviser Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000029142
<CLASS-CONTRACT-NAME>Class C
<CLASS-CONTRACT-TICKER-SYMBOL>JORCX
</CLASS-CONTRACT>
</SERIES>
</TARGET-DATA>
</MERGER>
<MERGER>
<ACQUIRING-DATA>
CENTRAL INDEX KEY:			0000277751
<SERIES>
<SERIES-ID>S000010474
<SERIES-NAME>Janus Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000077680
<CLASS-CONTRACT-NAME>Class I
</CLASS-CONTRACT>
</SERIES>
</ACQUIRING-DATA>
<TARGET-DATA>
CENTRAL INDEX KEY:			0001110822
<SERIES>
<SERIES-ID>S000010561
<SERIES-NAME>Janus Adviser Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000029143
<CLASS-CONTRACT-NAME>Class I
<CLASS-CONTRACT-TICKER-SYMBOL>JORFX
</CLASS-CONTRACT>
</SERIES>
</TARGET-DATA>
</MERGER>
<MERGER>
<ACQUIRING-DATA>
CENTRAL INDEX KEY:			0000277751
<SERIES>
<SERIES-ID>S000010474
<SERIES-NAME>Janus Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000077681
<CLASS-CONTRACT-NAME>Class R
</CLASS-CONTRACT>
</SERIES>
</ACQUIRING-DATA>
<TARGET-DATA>
CENTRAL INDEX KEY:			0001110822
<SERIES>
<SERIES-ID>S000010561
<SERIES-NAME>Janus Adviser Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000029144
<CLASS-CONTRACT-NAME>Class R
<CLASS-CONTRACT-TICKER-SYMBOL>JORRX
</CLASS-CONTRACT>
</SERIES>
</TARGET-DATA>
</MERGER>
<MERGER>
<ACQUIRING-DATA>
CENTRAL INDEX KEY:			0000277751
<SERIES>
<SERIES-ID>S000010474
<SERIES-NAME>Janus Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000077682
<CLASS-CONTRACT-NAME>Class S
</CLASS-CONTRACT>
</SERIES>
</ACQUIRING-DATA>
<TARGET-DATA>
CENTRAL INDEX KEY:			0001110822
<SERIES>
<SERIES-ID>S000010561
<SERIES-NAME>Janus Adviser Orion Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000029145
<CLASS-CONTRACT-NAME>Class S
<CLASS-CONTRACT-TICKER-SYMBOL>JORIX
</CLASS-CONTRACT>
</SERIES>
</TARGET-DATA>
</MERGER>
</MERGER-SERIES-AND-CLASSES-CONTRACTS>
</SERIES-AND-CLASSES-CONTRACTS-DATA>
</SEC-HEADER>
<DOCUMENT>
<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2009-05-08</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>13:15:00</finalEffectivenessDispTime>
        <form>N-14</form>
        <filer>
            <cik>0000277751</cik>
            <entityName>JANUS INVESTMENT FUND</entityName>
            <fileNumber>333-158030</fileNumber>
            <seriesClassContractData>
                <merger>
                    <acquiringCik>0000277751</acquiringCik>
                    <acquiringEntityName>JANUS INVESTMENT FUND</acquiringEntityName>
                    <acquiringSeriesId>S000010474</acquiringSeriesId>
                    <acquiringSeriesName>Janus Orion Fund</acquiringSeriesName>
                    <acquiringClassContractId>C000077678</acquiringClassContractId>
                    <acquiringClassContractName>Class A</acquiringClassContractName>
                    <targetCik>0001110822</targetCik>
                    <targetEntityName>JANUS ADVISER SERIES</targetEntityName>
                    <targetSeriesId>S000010561</targetSeriesId>
                    <targetSeriesName>Janus Adviser Orion Fund</targetSeriesName>
                    <targetClassContractId>C000029141</targetClassContractId>
                    <targetClassContractName>Class A</targetClassContractName>
                </merger>
                <merger>
                    <acquiringCik>0000277751</acquiringCik>
                    <acquiringEntityName>JANUS INVESTMENT FUND</acquiringEntityName>
                    <acquiringSeriesId>S000010474</acquiringSeriesId>
                    <acquiringSeriesName>Janus Orion Fund</acquiringSeriesName>
                    <acquiringClassContractId>C000077679</acquiringClassContractId>
                    <acquiringClassContractName>Class C</acquiringClassContractName>
                    <targetCik>0001110822</targetCik>
                    <targetEntityName>JANUS ADVISER SERIES</targetEntityName>
                    <targetSeriesId>S000010561</targetSeriesId>
                    <targetSeriesName>Janus Adviser Orion Fund</targetSeriesName>
                    <targetClassContractId>C000029142</targetClassContractId>
                    <targetClassContractName>Class C</targetClassContractName>
                </merger>
                <merger>
                    <acquiringCik>0000277751</acquiringCik>
                    <acquiringEntityName>JANUS INVESTMENT FUND</acquiringEntityName>
                    <acquiringSeriesId>S000010474</acquiringSeriesId>
                    <acquiringSeriesName>Janus Orion Fund</acquiringSeriesName>
                    <acquiringClassContractId>C000077680</acquiringClassContractId>
                    <acquiringClassContractName>Class I</acquiringClassContractName>
                    <targetCik>0001110822</targetCik>
                    <targetEntityName>JANUS ADVISER SERIES</targetEntityName>
                    <targetSeriesId>S000010561</targetSeriesId>
                    <targetSeriesName>Janus Adviser Orion Fund</targetSeriesName>
                    <targetClassContractId>C000029143</targetClassContractId>
                    <targetClassContractName>Class I</targetClassContractName>
                </merger>
                <merger>
                    <acquiringCik>0000277751</acquiringCik>
                    <acquiringEntityName>JANUS INVESTMENT FUND</acquiringEntityName>
                    <acquiringSeriesId>S000010474</acquiringSeriesId>
                    <acquiringSeriesName>Janus Orion Fund</acquiringSeriesName>
                    <acquiringClassContractId>C000077681</acquiringClassContractId>
                    <acquiringClassContractName>Class R</acquiringClassContractName>
                    <targetCik>0001110822</targetCik>
                    <targetEntityName>JANUS ADVISER SERIES</targetEntityName>
                    <targetSeriesId>S000010561</targetSeriesId>
                    <targetSeriesName>Janus Adviser Orion Fund</targetSeriesName>
                    <targetClassContractId>C000029144</targetClassContractId>
                    <targetClassContractName>Class R</targetClassContractName>
                </merger>
                <merger>
                    <acquiringCik>0000277751</acquiringCik>
                    <acquiringEntityName>JANUS INVESTMENT FUND</acquiringEntityName>
                    <acquiringSeriesId>S000010474</acquiringSeriesId>
                    <acquiringSeriesName>Janus Orion Fund</acquiringSeriesName>
                    <acquiringClassContractId>C000077682</acquiringClassContractId>
                    <acquiringClassContractName>Class S</acquiringClassContractName>
                    <targetCik>0001110822</targetCik>
                    <targetEntityName>JANUS ADVISER SERIES</targetEntityName>
                    <targetSeriesId>S000010561</targetSeriesId>
                    <targetSeriesName>Janus Adviser Orion Fund</targetSeriesName>
                    <targetClassContractId>C000029145</targetClassContractId>
                    <targetClassContractName>Class S</targetClassContractName>
                </merger>
            </seriesClassContractData>
        </filer>
    </effectiveData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----