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Note 9 - Income Taxes (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Federal research credits $ 1,600  
Change in valuation allowance attributable to operations (298) $ (3,114)
Internal Revenue Service (IRS)    
Operating Loss Carryforwards 162,300  
Internal Revenue Service (IRS) | No Expire    
Operating Loss Carryforwards 0  
State and Local Jurisdiction    
State research credits 800  
State and Local Jurisdiction | Expire On Various Dates    
Operating Loss Carryforwards $ 23,900