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Stockholders' Deficit - Schedule of Outstanding Awards Issued to Share-based Payment Award Plan and Inducement Grants (Details) - shares
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Options 17,655,000 23,782,000 25,030,000 20,873,000
2019 Plan [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Number of shares common stock available 13,054      
2019 Plan [Member] | Options [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Options 3,332      
2019 Plan [Member] | Restricted Stock Units [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
RSUs/PSUs 10,174      
2019 Plan [Member] | Performance Shares Unit [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
RSUs/PSUs 5,193      
2012 Plan [Member] | Options [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Options 4,601      
2009 Plan [Member] | Options [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Options 9,722      
2021 Inducement Grants [Member] | Restricted Stock Units [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
RSUs/PSUs 3,410      
2021 Inducement Grants [Member] | Performance Shares Unit [Member]        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
RSUs/PSUs 3,010