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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MtpM0qYsz4M3pRecZ2vq3ufI/DXfu7jMtXxTIooD2iN0HBSfTbxOEOOJLql5vzay
 FrUoI2pMBi3Rk1Fa0SF/HA==

<SEC-DOCUMENT>0001209191-06-019863.txt : 20060324
<SEC-HEADER>0001209191-06-019863.hdr.sgml : 20060324
<ACCEPTANCE-DATETIME>20060324180253
ACCESSION NUMBER:		0001209191-06-019863
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060323
FILED AS OF DATE:		20060324
DATE AS OF CHANGE:		20060324

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Stein Barry A
		CENTRAL INDEX KEY:			0001331225

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09927
		FILM NUMBER:		06710305

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		617-868-5264

	MAIL ADDRESS:	
		STREET 1:		6 CHANNING PLACE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02138

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COMPREHENSIVE CARE CORP
		CENTRAL INDEX KEY:			0000022872
		STANDARD INDUSTRIAL CLASSIFICATION:	HOSPITAL & MEDICAL SERVICE PLANS [6324]
		IRS NUMBER:				952594724
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0531

	BUSINESS ADDRESS:	
		STREET 1:		200 SOUTH HOOVER BLVD
		STREET 2:		SUITE 200
		CITY:			TAMPA
		STATE:			FL
		ZIP:			33609
		BUSINESS PHONE:		813-288-4808

	MAIL ADDRESS:	
		STREET 1:		200 SOUTH HOOVER BLVD
		STREET 2:		SUITE 200
		CITY:			TAMPA
		STATE:			FL
		ZIP:			33609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NEURO PSYCHIATRIC & HEALTH SERVICES
		DATE OF NAME CHANGE:	19730501

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NEURO PSYCHIATRIC & HEALTH SERVICES INC
		DATE OF NAME CHANGE:	19700402

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JADE OIL CO
		DATE OF NAME CHANGE:	19700402
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-03-23</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000022872</issuerCik>
        <issuerName>COMPREHENSIVE CARE CORP</issuerName>
        <issuerTradingSymbol>CHCR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001331225</rptOwnerCik>
            <rptOwnerName>Stein Barry A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>204 SOUTH HOOVER BLVD</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>TAMPA</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33609</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Options to purchase common stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.80</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2006-03-23</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>25000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2007-03-23</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2016-03-23</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>25000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>25000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The options vest in 1/5 increments beginning on the first anniversary of the date of grant, provided the Optionee remains a Director on those vesting dates.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Scott Bates, as Attorney-in-fact for Barry A. Stein</signatureName>
        <signatureDate>2006-03-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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