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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


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                                    FORM 8-K



                                 CURRENT REPORT,
                       PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934



         DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): MAY 19, 1999
                                 (MAY 17, 1999)


                         COMPREHENSIVE CARE CORPORATION
               (Exact Name of Registrant as Specified in Charter)


            DELAWARE                     0-5751                  95-2594724
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(State or Other Jurisdiction    (Commission File Number)      (I.R.S. Employer
     of Incorporation)                                       Identification No.)


       4200 WEST CYPRESS STREET, STE 300
                 TAMPA, FLORIDA                                 33607
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    (Address of Principal Executive Offices)                  (Zip Code)


       Registrant's telephone number, including area code: (813) 876-5036

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ITEM 4.  CHANGE IN REGISTRANT'S CERTIFYING ACCOUNTANT.

         The Company has engaged Richard A. Eisner & Company, LLP ("RAE") as
independent accountants to audit its financial statements for the fiscal year
ending May 31, 1999. The engagement of RAE is in lieu of Ernst & Young, LLP
("E&Y"), who was dismissed by the Company. E&Y has audited the Company's
financial statements for each of the two most recent fiscal years, and with
respect to which had included in its reports a "going concern" uncertainty and,
for the fiscal year ended May 31, 1998, included an explanatory paragraph
regarding the Company's change in the method used for estimating its claims
liability.

         The Company has not, during its two preceding fiscal years and any
subsequent interim periods, had any dispute or disagreement with E&Y on any
matter of accounting principles or practices, financial statement disclosure, or
auditing scope or procedure which if not resolved to the satisfaction of E&Y
would have caused E&Y to make reference to the matter in their report.

         The engagement of RAE in lieu of E&Y was prompted by economic
considerations and was concurred to by the Board of Directors of the Company.

         Attached to this report is the letter of E&Y required by Item
304(a)(3). The effective date of the engagement of RAE is the date of this
report.


                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report on Form 8-K to be signed on its
behalf by the undersigned hereunto duly authorized.


                                   COMPREHENSIVE CARE CORPORATION


                                   By:  /s/ CHRISS W. STREET
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                                        Chriss W. Street
                                        Chairman, President, and Chief 
                                        Executive Officer

Date: May 19, 1999