-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 FlAX9R9BfaDsYp1ZXkmmDj23LaXT0Y037byNrMmcC1z1OkCYwRXIKbSUeJawt7o7
 RdmQmRp+2tw+Ve/aEgqiHA==

<SEC-DOCUMENT>0001267093-03-000002.txt : 20031126
<SEC-HEADER>0001267093-03-000002.hdr.sgml : 20031126
<ACCEPTANCE-DATETIME>20031126111021
ACCESSION NUMBER:		0001267093-03-000002
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20031125
FILED AS OF DATE:		20031126

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AVENTIS HOLDINGS INC
		CENTRAL INDEX KEY:			0001267075
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21699
		FILM NUMBER:		031025080

	MAIL ADDRESS:	
		STREET 1:		3711 KENNETH PIKE
		CITY:			GREENVILLE
		STATE:			DE
		ZIP:			19807

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AVENTIS PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0001267093

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21699
		FILM NUMBER:		031025081

	MAIL ADDRESS:	
		STREET 1:		300 SOMERSET CORP BLVD
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			AVENTIS INC
		CENTRAL INDEX KEY:			0000217028
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21699
		FILM NUMBER:		031025079

	BUSINESS ADDRESS:	
		STREET 1:		500 ARCOLA RD
		STREET 2:		P O BOX 1200 M/S 5B14
		CITY:			COLLEGEVILLE
		STATE:			PA
		ZIP:			19426-0107
		BUSINESS PHONE:		6104548000
	FORMER NAME:		
	FORMER CONFORMED NAME:	RHONE POULENC RORER INC
	DATE OF NAME CHANGE:	19920703
</FORMER-NAME>
	FORMER NAME:		
	FORMER CONFORMED NAME:	RORER GROUP INC
	DATE OF NAME CHANGE:	19900731
</FORMER-NAME>
	FORMER NAME:		
	FORMER CONFORMED NAME:	RORER AMCHEM INC
	DATE OF NAME CHANGE:	19770604
</FORMER-NAME>

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VIROPHARMA INC
		CENTRAL INDEX KEY:			0000946840
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				232789550
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		405 EAGLEVIEW BLVD
		STREET 2:		PO BOX 5000
		CITY:			EXTON
		STATE:			PA
		ZIP:			19341
		BUSINESS PHONE:		6104587300

	MAIL ADDRESS:	
		STREET 1:		405 EAGLEVIEW BOULEVARD
		CITY:			EXTON
		STATE:			PA
		ZIP:			19341
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>

<ownershipDocument>

    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2003-11-25</periodOfReport>


    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000946840</issuerCik>
        <issuerName>VIROPHARMA INC</issuerName>
        <issuerTradingSymbol>VPHM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001267093</rptOwnerCik>
            <rptOwnerName>AVENTIS PHARMACEUTICALS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>300 SOMERSET CORP BLVD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BRIDGEWATER</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08807</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>
    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001267075</rptOwnerCik>
            <rptOwnerName>AVENTIS HOLDINGS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>3711 KENNETH PIKE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GREENVILLE</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19807</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Beneficial owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>
    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000217028</rptOwnerCik>
            <rptOwnerName>AVENTIS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>300 SOMERSET CORPORATE BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BRIDGEWATER</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08807</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Beneficial owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>

        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common</value>
            </securityTitle>
            <transactionDate>
                <value>2003-11-25</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>15012</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.15</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2824000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>

    </nonDerivativeTable>


    <remarks>Shares are owned directly by Aventis Pharmaceuticals Inc. and indirectly by Aventis Holdings Inc. and Aventis Inc.</remarks>

    <ownerSignature>
        <signatureName>Pascal Soriot</signatureName>
        <signatureDate>2003-11-26</signatureDate>
    </ownerSignature>

</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----