8-K

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                      SECURITIES AND EXCHANGE COMMISSION

                          Washington, D.C.  20549


                                Form 8-K
 
                             CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported)         April 30, 1999
                                                 --------------------------

                               WesBanco, Inc.
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           (Exact name of registrant as specified in its charter)


West Virginia                       0-8467                55-0571723
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(State or other jurisdiction     (Commission            (IRS Employer
of incorporation)                 File Number)          Identification No.)



1 Bank Plaza, Wheeling,  WV                            26003
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(Address of principal executive offices)             (Zip Code)


Registrant's telephone number, including area code      (304) 234-9000
                                                    -----------------------
Former name or former address, if changed since last report Not Applicable
                                                            ---------------



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Item 5 - Other Events

     On April 30, 1999, WesBanco, Inc. consummated its acquisition
of The Heritage Bank of Harrison County, Inc. ("Heritage") with and into
WesBanco affiliate, WesBanco Bank Fairmont.  The acquisition, which
was accounted for as a purchase transaction, was effected through an
exchange of stock, whereby Heritage shareholders received 1.76639 shares
of WesBanco common stock for each share of Heritage common stock.  WesBanco
issued a total of 423,106 common shares in the transaction.  The acquisition
is more fully described in a Registration Statement filed with respect to the
registration of the shares under Registration Statement No. 333-74323, which
is incorporated herein by reference.


Item 7 - Financial Statements, Pro Forma Financial Information
         and Exhibits

  Exhibits  -  Incorporated herein by reference is the Registrant's
               Prospectus/Proxy Statement effective March 25, 1999,
               used in connection with Registration Number 333-74323.

        20  -  Press release dated May 3, 1999, regarding the
               consummation of WesBanco's acquisition of The Heritage
               Bank of Harrison County, Inc.

                              Signatures

     Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed
on its behalf by the undersigned hereunto duly authorized.

                              WesBanco, Inc.
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                              (Registrant)


May 7, 1999                  /s/ Edward M. George
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    Date                      Edward M. George
                              President & Chief Executive Officer

EX-20

                                                          EXHIBIT 20



NEWS for Immediate Release
May 3, 1999		

                                          For Further Information Contact:
                                          Edward M. George
                                          President & CEO (304) 234-9208

                                          Nasdaq Trading Symbol: WSBC

WesBanco Consummates Merger with The Heritage Bank of Harrison County

Wheeling, WV. . .   WesBanco, Inc. ("WesBanco")(Nasdaq:WSBC), a multi-bank
holding company headquartered in Wheeling, West Virginia, today announced
the consummation of its acquisition of The Heritage Bank of Harrison County
("Heritage"), Clarksburg, West Virginia, with and into WesBanco affiliate,
WesBanco Bank Fairmont, Fairmont, West Virginia. Edward M. George, President
& CEO of WesBanco and Thomas J. Hansberry, President & CEO of WesBanco Bank
Fairmont, jointly announced the merger that was consummated on April 30, 1999.
Mr. Hansberry, the former President & CEO of Heritage, was recently elected
to the Boards of Directors of WesBanco Bank Fairmont and WesBanco, Inc.

At March 31, 1999, WesBanco had consolidated assets of $2.2 billion, deposits
of $1.8 billion and shareholders' equity of $290 million. At March 31, 1999,
Heritage had total assets of $34.2 million, deposits of $29.9 million and
shareholders' equity of $4.2 million. The merger was accounted for as a
purchase transaction.

With the addition of Heritage, WesBanco currently operates four banks through
60 banking offices in the States of West Virginia and Ohio. Its principal
banking subsidiaries include: WesBanco Bank Wheeling, WesBanco Bank Fairmont,
WesBanco Bank Parkersburg and WesBanco Bank Charleston. In addition, WesBanco
operates a mortgage company, WesBanco Mortgage Company, and an insurance
agency, Hunter Agency, Inc. Other affiliates include CommBanc Investments,
Inc. and Hometown Finance Company.

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