8-K

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                   SECURITIES AND EXCHANGE COMMISSION

                        Washington, DC  20549


                              Form 8-K

                           CURRENT REPORT


     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported)     August 30, 1996
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                                WesBanco, Inc.
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            (Exact name of registrant as specified in its charter)


    West Virginia                  0-8467               55-0571723
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(State or other jurisdiction     (Commission          (IRS Employer
of incorporation)                File Number)        Identification No.)


  1 Bank Plaza, Wheeling, WV                                26003
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(Address of principal executive offices)                  (Zip Code)     


Registrant's telephone number, including area code    (304) 234-9000
                                                   -------------------------
Former name or former address, if changed since last report  Not Applicable
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Item 2 - Acquisition or Disposition of Assets
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     On August 30, 1996, WesBanco consummated the acquisition of Bank of 
Weirton through a statutory merger with a wholly owned subsidiary of the 
Registrant.  This acquisition was effected through an exchange of stock of 
the Registrant.  The Registrant has registered 1,690,000 common shares for 
the purpose of issuance with respect to this acquisition.  The acquisition 
is more fully described in a Registration Statement filed with respect to 
the registration of the shares under Registration Statement No. 333-3905, 
which is incorporated herein by reference.

Item 7 - Financial Statements, Pro Forma Financial Information and Exhibits
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  Exhibit - Incorporated herein by reference is Registrant's Prospectus/Proxy
            Statement effective July 5, 1996, used in connection with
            Registration Number 333-3905.

     20   - Press release dated September 3, 1996, regarding the consummation
            of the acquisition of Bank of Weirton by WesBanco, Inc.


                                Signatures

     Pursuant to the requirements of the Securities Exchange Act of 1934, 
the registrant has duly caused this report to be signed on its behalf by 
the undersigned hereunto duly authorized.

                              
                                            WesBanco, Inc.
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                                            (Registrant)



September 4, 1996                           /s/ Edward M. George
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     Date                                   Edward M. George
                                            President & Chief Executive Officer

EX-20

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                                                     [WesBanco Logo]
                                                
                                                        EXHIBIT - 20
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NEWS For Immediate Release
September 3, 1996                      For Further Information Contact:
                                       Edward M. George
                                       President & CEO     (304) 234-9208

                                       Nasdaq Trading Symbol: WSBC


WesBanco Consummates Merger With Bank of Weirton

Wheeling, WV . . . . Edward M. George, President and Chief Executive Officer 
of WesBanco, Inc., a multi-state multi-bank holding company headquartered in 
Wheeling, West Virginia, announced today the consummation of the merger of 
Bank of Weirton, Weirton, WV, into WesBanco affiliate, WesBanco Bank Wheeling.

As a result of the merger, which will be accounted for as a pooling-of-
interests, WesBanco exchanged 130 shares of WesBanco common stock for each 
share of Weirton's common stock in a tax-free exchange. The transaction is 
valued at more than $45,630,000 based on the recent market price of $27.00 
per share for WesBanco common stock.

Under the terms of the merger, George M. Molnar will serve as President of 
WesBanco Weirton and has become Chairman of the Weirton Advisory Board. 
Additionally, George M. Molnar and R. Peterson Chalfant have been appointed 
to the Board of Directors of WesBanco, Inc., with George M. Molnar also 
appointed to the Executive Committee of the Board of Directors of WesBanco, 
Inc. Also, George M. Molnar and Donald R. Donell have been elected to the 
Board of Directors of WesBanco Bank Wheeling, and George M. Molnar has been 
elected to the Executive Committee of WesBanco Bank Wheeling.

With the addition of Bank of Weirton, the acquisition of Universal Mortgage 
Company, now WesBanco Mortgage Company, and the completion of the announced 
agreement of July 18, 1996 to acquire Vandalia National Corporation, 
Morgantown, WV, WesBanco will have assets in excess of $1.6 billion, will 
operate 42 banking offices in West Virginia and Ohio and operate five mortgage 
loan offices in West Virginia.

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