FEDERATED MUNICIPAL SECURITIES FUND, INC.

                          Federated Investors Funds
                             5800 Corporate Drive
                     Pittsburgh, Pennsylvania 15237-7000

                                 May 30, 2006


EDGAR Operations Branch
U.S. Securities and Exchange Commission
Division of Investment Management
100 F Street, N.E.
Washington, DC  20549

     RE: Federated Municipal Securities Fund, Inc. (the "Fund")
            Class A Shares
            Class B Shares
            Class C Shares
           1933 Act File No. 2-57181
           1940 Act File No. 811-2677

Dear Sir or Madam:

      Pursuant   to  Rule   497(j)   of  the   Securities   Act  of  1933,   the
above-referenced  Fund hereby  certifies that the definitive  form of Prospectus
and  Statement of  Additional  Information  dated May 31, 2006,  that would have
been filed under Rule 497(c),  does not differ from the form of  Prospectus  and
Statement of Additional  Information  contained in the most recent  Registration
Statement for the Fund. This  Registration  Statement was  electronically  filed
under Rule 485(b) as Post-Effective amendment No. 61 on May 26, 2006.

      If you have any questions regarding this  certification,  please contact
me at (412) 288-6807.

                                                Very truly yours,



                                                /s/ George F. Magera
                                                George F. Magera
                                                Assistant Secretary

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