485B24E

                                                      1933 Act File No. 2-57181
                                                      1940 Act File No. 811-2677

                  SECURITIES AND EXCHANGE COMMISSION
                        Washington, D.C. 20549

                               Form N-1A

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933                     x
                                                                         ----

      Pre-Effective Amendment No.         ...............................
      Post-Effective Amendment No. 49     ...............................   x
                                  --------                               ----

                                and/or

REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940

      Amendment No.      .....................................................

               Federated Municipal Securities Fund, Inc.
          (Exact Name of Registrant as Specified in Charter)

    Federated Investors Tower, Pittsburgh, Pennsylvania 15222-3779
               (Address of Principal Executive Offices)

                                                (412) 288-1900
                    (Registrant's Telephone Number)

                      John W. McGonigle, Esquire,
                      Federated Investors Tower,
                  Pittsburgh, Pennsylvania 15222-3779
                (Name and Address of Agent for Service)

It is proposed that this filing will become effective:

 x  immediately upon filing pursuant to paragraph (b) on
    _________________ pursuant to paragraph (b) 60 days after filing
    pursuant to paragraph (a) (i) on pursuant to paragraph (a) (i). 75
    days after filing pursuant to paragraph (a)(ii) on
    _________________ pursuant to paragraph (a)(ii) of Rule 485.

If appropriate, check the following box:

    This post-effective amendment designates a new effective date for
a previously filed post-effective amendment.

Registrant has filed with the Securities and Exchange Commission a
declaration pursuant to Rule 24f-2 under the Investment Company Act of
1940, and:

  x filed the Notice required by that Rule on May 15, 1997; or intends
    to file the Notice required by that Rule on or about ____________;
    or during the most recent fiscal year did not sell any securities
    pursuant to Rule 24f-2 under the
   Investment Company Act of 1940, and, pursuant to Rule 24f-2(b)(2),
need not file the Notice.


                                            Copies To:

Matthew G. Maloney, Esquire
Dickstein Shapiro Morin & Oshinsky LLP
2101 L Street, N.W.
Washington, D.C.  20037





CALCULATION OF REGISTRATION FEE UNDER THE SECURITIES ACT OF 1933


                                                       Proposed
Title of                              Proposed         Maximum
Securities               Amount       Maximum          Aggregate     Amount of
Being                    Being        Offering Price   Offering    Registration
Registered               Registered   Per Unit         Price*          Fee

Shares of
Common Stock
($0.01 par value)        2,038,439    $10.86           $22,137,448     $0.00


*Registrant has elected to calculate its filing fee in the manner
described in Rule 24e-2 of the Investment Company Act of 1940. The
total amount of securities redeemed during the previous fiscal year
was 20,071,909. The total amount of redeemed securities used for
reductions pursuant to paragraph (a) of Rule 24e-2 or paragraph (c) of
Rule 24f-2 during the current year was 18,033,470. The amount of
redeemed securities being used for reduction of the registration fee
in this Amendment is 2,038,439.






                         CONTENTS OF AMENDMENT

     This Post-Effective Amendment No. 49 to the Registration Statement of
Federated Municipal Securities Fund, Inc. is comprised of the following papers
and documents:

         1.   The facing sheet to register a definite
              number of shares of common stock, par value $0.01, of Federated
              Municipal Securities Fund, Inc.;

         2.   The legal opinion of counsel for the Registrant, as
              to the legality of shares being offered; and as to
              the eligibility to become effective pursuant to
              Paragraph (b) of Rule 485; and

         3.   Signature page.





                              SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the
Registrant, Federated Municipal Securities Fund, Inc. certifies that
it meets all of the requirements for effectiveness of this Amendment
to its Registration Statement pursuant to Rule 485(b) under the
Securities Act of 1933 and has duly caused this Amendment to its
Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Pittsburgh and Commonwealth
of Pennsylvania on the 15th day of May, 1997.

               Federated Municipal Securities Fund, Inc.

                  BY:  /s/ S. Elliott Cohan
                       S. Elliott Cohan, Assistant Secretary
                       Attorney in Fact for John F. Donahue
                       May 15, 1997


     Pursuant to the requirements of the Securities Act of 1933, this
Amendment to its Registration Statement has been signed below by the
following person in the capacity and on the date indicated:

       NAME                             TITLE                             DATE

By:   /s/ S. Elliott Cohan
      S. Elliott Cohan                 Attorney In Fact           May 15, 1997
      Assistant Secretary              For the Persons
                                       Listed Below

       NAME                             TITLE

John F. Donahue*                       Chairman and Director
                                       (Chief Executive Officer)

J. Christopher Donahue*                President and Director

John W. McGonigle*                     Treasurer (Chief Financial Officer)

Thomas G. Bigley *                     Director

John T. Conroy, Jr.*                   Director

William J. Copeland*                   Director

James E. Dowd*                         Director

Lawrence D. Ellis, M.D.*               Director

Edward L. Flaherty, Jr.*               Director

Peter E. Madden*                       Director

Gregor F. Meyer*                       Director

John E. Murray, Jr.*                   Director

Wesley W. Posvar*                      Director

Marjorie P. Smuts*                     Director


* By Power of Attorney

EX-99.OPNLETTER

      FEDERATED ADMINISTRATIVE
                         SERVICES

                                              FEDERATED INVESTORS TOWER
                                              PITTSBURGH, PA 15222-3779
                                              412-288-1900






                          May 15, 1997



Federated Municipal Securities Fund, Inc.
Federated Investors Tower
Pittsburgh, PA  15222-3779

Gentlemen:

         You have requested my opinion in conjunction with the
registration by Federated Municipal Securities Fund, Inc. (the
"Corporation") of an additional 2,038,439 shares of its common stock
pursuant to Post-effective Amendment No. 49 to the Corporation's
registration statement filed with the Securities and Exchange
Commission under the Securities Act of 1933 (File No.2-57181). The
subject Post-effective Amendment will be filed pursuant to Paragraph
(b) of Rule 485 and become effective pursuant to said Rule immediately
upon filing.

         As counsel I have participated in the preparation and filing
of the Corporation's amended registration statement under the
Securities Act of 1933 referred to above. Further, I have examined and
am familiar with the Corporation's Articles of Incorporation dated
September 10, 1976 ("Articles of Incorporation"), its Bylaws and other
corporate documents and records deemed relevant. I have also reviewed
questions of law and consulted with counsel thereon as deemed
necessary or appropriate by me for the purpose of this opinion.

         On the basis of the foregoing, it is my opinion that:

         1.       The Corporation is duly organized and validly existing
under the laws of the State of Maryland.

         2.       The Corporation is authorized to issue 1,000,000,000 shares
of common stock of a par value of $0.001 per share.

         3. The Shares which are currently being registered by the
Registration Statement referred to above may be legally and validly
issued from time to time in accordance with the Articles of
Incorporation upon receipt of consideration sufficient to comply with
the Articles of Incorporation and subject to compliance with the
Securities Act of 1933, as amended, the Investment Company Act of
1940, as amended, and applicable state laws regulating the sale of
securities. Such Shares, when so issued, will be fully paid and
non-assessable.

         I hereby consent to the filing of this opinion as part of the
Corporation's registration statement referred to above and as a part
of any application or registration statement filed under the
securities laws of the States of the United States.

         The foregoing opinion is limited to the Federal laws of the
United States and the laws of the State of Maryland, and I am
expressing no opinion as to the effect of the laws of any other
jurisdiction.

                                                         Very truly yours,


                                                         /s/ S. Elliott Cohan
                                                         S. Elliott Cohan
                                                         Fund Attorney

EX-27.FDS

 



       
                             

<ARTICLE>                       6

     <NUMBER>                   001
     <NAME>                     Federated Municipal Securities Fund, Inc.
                                Class A Shares

<PERIOD-TYPE>                   12-mos
<FISCAL-YEAR-END>               Mar-31-1997
<PERIOD-END>                    Mar-31-1997
<INVESTMENTS-AT-COST>           692,288,766
<INVESTMENTS-AT-VALUE>          680,278,125
<RECEIVABLES>                   16,686,171
<ASSETS-OTHER>                  241,903
<OTHER-ITEMS-ASSETS>            0
<TOTAL-ASSETS>                  697,206,199
<PAYABLE-FOR-SECURITIES>        0
<SENIOR-LONG-TERM-DEBT>         0
<OTHER-ITEMS-LIABILITIES>       3,611,351
<TOTAL-LIABILITIES>             3,611,351
<SENIOR-EQUITY>                 0
<PAID-IN-CAPITAL-COMMON>        708,965,828
<SHARES-COMMON-STOCK>           57,773,220
<SHARES-COMMON-PRIOR>           61,344,756
<ACCUMULATED-NII-CURRENT>       0
<OVERDISTRIBUTION-NII>          (3,325,545)
<ACCUMULATED-NET-GAINS>         (34,795)
<OVERDISTRIBUTION-GAINS>        0
<ACCUM-APPREC-OR-DEPREC>        (12,010,640)
<NET-ASSETS>                    595,515,100
<DIVIDEND-INCOME>               0
<INTEREST-INCOME>               45,675,471
<OTHER-INCOME>                  0
<EXPENSES-NET>                  7,604,574
<NET-INVESTMENT-INCOME>         38,070,897
<REALIZED-GAINS-CURRENT>        (30,587)
<APPREC-INCREASE-CURRENT>       (25,442,823)
<NET-CHANGE-FROM-OPS>           12,597,487
<EQUALIZATION>                  0
<DISTRIBUTIONS-OF-INCOME>       33,864,603
<DISTRIBUTIONS-OF-GAINS>        2,983,224
<DISTRIBUTIONS-OTHER>           0
<NUMBER-OF-SHARES-SOLD>         11,574,693
<NUMBER-OF-SHARES-REDEEMED>     17,732,936
<SHARES-REINVESTED>             2,586,707
<NET-CHANGE-IN-ASSETS>          (54,153,394)
<ACCUMULATED-NII-PRIOR>         18,772
<ACCUMULATED-GAINS-PRIOR>       6,666,727
<OVERDISTRIB-NII-PRIOR>         0
<OVERDIST-NET-GAINS-PRIOR>      0
<GROSS-ADVISORY-FEES>           4,379,885
<INTEREST-EXPENSE>              0
<GROSS-EXPENSE>                 8,489,957
<AVERAGE-NET-ASSETS>            724,853,322
<PER-SHARE-NAV-BEGIN>           10.820
<PER-SHARE-NII>                 0.550
<PER-SHARE-GAIN-APPREC>         (0.360)
<PER-SHARE-DIVIDEND>            0.550
<PER-SHARE-DISTRIBUTIONS>       0.100
<RETURNS-OF-CAPITAL>            0.050
<PER-SHARE-NAV-END>             10.310
<EXPENSE-RATIO>                 0.93
<AVG-DEBT-OUTSTANDING>          0
<AVG-DEBT-PER-SHARE>            0.000
        





 

EX-27.FDS

 



       
                             

<ARTICLE>                       6

     <NUMBER>                   002
     <NAME>                     Federated Municipal Securities Fund, Inc.
                                Class B Shares

<PERIOD-TYPE>                   12-mos
<FISCAL-YEAR-END>               Mar-31-1997
<PERIOD-END>                    Mar-31-1997
<INVESTMENTS-AT-COST>           692,288,766
<INVESTMENTS-AT-VALUE>          680,278,125
<RECEIVABLES>                   16,686,171
<ASSETS-OTHER>                  241,903
<OTHER-ITEMS-ASSETS>            0
<TOTAL-ASSETS>                  697,206,199
<PAYABLE-FOR-SECURITIES>        0
<SENIOR-LONG-TERM-DEBT>         0
<OTHER-ITEMS-LIABILITIES>       3,611,351
<TOTAL-LIABILITIES>             3,611,351
<SENIOR-EQUITY>                 0
<PAID-IN-CAPITAL-COMMON>        708,965,828
<SHARES-COMMON-STOCK>           7,521,540
<SHARES-COMMON-PRIOR>           5,389,543
<ACCUMULATED-NII-CURRENT>       0
<OVERDISTRIBUTION-NII>          (3,325,545)
<ACCUMULATED-NET-GAINS>         (34,795)
<OVERDISTRIBUTION-GAINS>        0
<ACCUM-APPREC-OR-DEPREC>        (12,010,640)
<NET-ASSETS>                    77,535,846
<DIVIDEND-INCOME>               0
<INTEREST-INCOME>               45,675,471
<OTHER-INCOME>                  0
<EXPENSES-NET>                  7,604,574
<NET-INVESTMENT-INCOME>         38,070,897
<REALIZED-GAINS-CURRENT>        (30,587)
<APPREC-INCREASE-CURRENT>       (25,442,823)
<NET-CHANGE-FROM-OPS>           12,597,487
<EQUALIZATION>                  0
<DISTRIBUTIONS-OF-INCOME>       3,157,991
<DISTRIBUTIONS-OF-GAINS>        332,555
<DISTRIBUTIONS-OTHER>           0
<NUMBER-OF-SHARES-SOLD>         3,354,939
<NUMBER-OF-SHARES-REDEEMED>     1,426,287
<SHARES-REINVESTED>             203,345
<NET-CHANGE-IN-ASSETS>          (54,153,394)
<ACCUMULATED-NII-PRIOR>         18,772
<ACCUMULATED-GAINS-PRIOR>       6,666,727
<OVERDISTRIB-NII-PRIOR>         0
<OVERDIST-NET-GAINS-PRIOR>      0
<GROSS-ADVISORY-FEES>           4,379,885
<INTEREST-EXPENSE>              0
<GROSS-EXPENSE>                 8,489,957
<AVERAGE-NET-ASSETS>            724,853,322
<PER-SHARE-NAV-BEGIN>           10.820
<PER-SHARE-NII>                 0.470
<PER-SHARE-GAIN-APPREC>         0.370
<PER-SHARE-DIVIDEND>            0.470
<PER-SHARE-DISTRIBUTIONS>       0.100
<RETURNS-OF-CAPITAL>            0.040
<PER-SHARE-NAV-END>             10.310
<EXPENSE-RATIO>                 1.82
<AVG-DEBT-OUTSTANDING>          0
<AVG-DEBT-PER-SHARE>            0.000
        




 

EX-27.FDS

 





       
                             

<ARTICLE>                       6

     <NUMBER>                   003
     <NAME>                     Federated Municipal Securities Fund, Inc.
                                Class C Shares

<PERIOD-TYPE>                   12-mos
<FISCAL-YEAR-END>               Mar-31-1997
<PERIOD-END>                    Mar-31-1997
<INVESTMENTS-AT-COST>           692,288,766
<INVESTMENTS-AT-VALUE>          680,278,125
<RECEIVABLES>                   16,686,171
<ASSETS-OTHER>                  241,903
<OTHER-ITEMS-ASSETS>            0
<TOTAL-ASSETS>                  697,206,199
<PAYABLE-FOR-SECURITIES>        0
<SENIOR-LONG-TERM-DEBT>         0
<OTHER-ITEMS-LIABILITIES>       3,611,351
<TOTAL-LIABILITIES>             3,611,351
<SENIOR-EQUITY>                 0
<PAID-IN-CAPITAL-COMMON>        708,965,828
<SHARES-COMMON-STOCK>           1,993,037
<SHARES-COMMON-PRIOR>           2,395,801
<ACCUMULATED-NII-CURRENT>       0
<OVERDISTRIBUTION-NII>          (3,325,545)
<ACCUMULATED-NET-GAINS>         (34,795)
<OVERDISTRIBUTION-GAINS>        0
<ACCUM-APPREC-OR-DEPREC>        (12,010,640)
<NET-ASSETS>                    20,543,902
<DIVIDEND-INCOME>               0
<INTEREST-INCOME>               45,675,471
<OTHER-INCOME>                  0
<EXPENSES-NET>                  7,604,574
<NET-INVESTMENT-INCOME>         38,070,897
<REALIZED-GAINS-CURRENT>        (30,587)
<APPREC-INCREASE-CURRENT>       (25,442,823)
<NET-CHANGE-FROM-OPS>           12,597,487
<EQUALIZATION>                  0
<DISTRIBUTIONS-OF-INCOME>       1,067,075
<DISTRIBUTIONS-OF-GAINS>        99,766
<DISTRIBUTIONS-OTHER>           0
<NUMBER-OF-SHARES-SOLD>         423,472
<NUMBER-OF-SHARES-REDEEMED>     86,450
<SHARES-REINVESTED>             912,686
<NET-CHANGE-IN-ASSETS>          (54,153,394)
<ACCUMULATED-NII-PRIOR>         18,772
<ACCUMULATED-GAINS-PRIOR>       6,666,727
<OVERDISTRIB-NII-PRIOR>         0
<OVERDIST-NET-GAINS-PRIOR>      0
<GROSS-ADVISORY-FEES>           4,379,885
<INTEREST-EXPENSE>              0
<GROSS-EXPENSE>                 8,489,957
<AVERAGE-NET-ASSETS>            724,853,322
<PER-SHARE-NAV-BEGIN>           10.820
<PER-SHARE-NII>                 0.460
<PER-SHARE-GAIN-APPREC>         0.360
<PER-SHARE-DIVIDEND>            0.460
<PER-SHARE-DISTRIBUTIONS>       0.100
<RETURNS-OF-CAPITAL>            0.050
<PER-SHARE-NAV-END>             10.310
<EXPENSE-RATIO>                 1.81
<AVG-DEBT-OUTSTANDING>          0
<AVG-DEBT-PER-SHARE>            0.000