The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Adicet Bio, Inc. | COM | 007002108 | 10,366 | 728,944 | SH | DFND | 1 | 0 | 728,944 | 0 | |
| Aldeyra Therapeutics, Inc. | COM | 01438T106 | 2,108 | 394,834 | SH | DFND | 1 | 0 | 394,834 | 0 | |
| Arrowhead Pharmaceuticals, Inc. | COM | 04280A100 | 8,183 | 247,598 | SH | DFND | 1 | 0 | 247,598 | 0 | |
| BiomX Inc. | COM | 09090D103 | 725 | 2,133,402 | SH | DFND | 1 | 0 | 2,133,402 | 0 | |
| Catalyst Biosciences, Inc. | COM | 14888D208 | 34 | 66,951 | SH | DFND | 1 | 0 | 66,951 | 0 | |
| Cue Health, Inc. | COM | 229790100 | 16,702 | 5,548,864 | SH | DFND | 1 | 0 | 5,548,864 | 0 | |
| CVRx, Inc. | COM | 126638105 | 32,614 | 3,495,575 | SH | DFND | 1 | 0 | 3,495,575 | 0 | |
| Fate Therapeutics, Inc. | COM | 31189P102 | 75,725 | 3,379,064 | SH | DFND | 1 | 0 | 3,379,064 | 0 | |
| Fusion Pharmaceuticals Inc. | COM | 36118A100 | 11,048 | 3,670,516 | SH | DFND | 1 | 0 | 3,670,516 | 0 | |
| Graybug Vision, Inc. | COM | 38942Q103 | 47 | 49,547 | SH | DFND | 1 | 0 | 49,547 | 0 | |
| Legend Biotech Corporation | ADS | 52490G102 | 66,470 | 1,629,173 | SH | DFND | 1 | 0 | 1,629,173 | 0 | |
| MeiraGTx Holdings plc | COM | G59665102 | 24,377 | 2,898,550 | SH | DFND | 1 | 0 | 2,898,550 | 0 | |
| Nano-X Imaging Ltd. | ORD SHS | M70700105 | 2,207 | 192,429 | SH | DFND | 1 | 0 | 192,429 | 0 | |
| PhaseBio Pharmaceuticals, Inc. | COM | 717224109 | 283 | 1,607,044 | SH | DFND | 1 | 0 | 1,607,044 | 0 | |
| Point Biopharma Global Inc. | COM | 730541109 | 7,730 | 1,000,000 | SH | DFND | 1 | 0 | 1,000,000 | 0 | |
| Procept BioRobotics Corporation | COM | 74276L105 | 35,818 | 863,908 | SH | DFND | 1 | 0 | 863,908 | 0 | |
| Protagonist Therapeutics Inc. | COM | 74366E102 | 20,647 | 2,449,183 | SH | DFND | 1 | 0 | 2,449,183 | 0 | |
| Senseonics Holdings, Inc. | COM | 81727U105 | 72 | 54,621 | SH | DFND | 1 | 0 | 54,621 | 0 | |
| Tracon Pharmaceuticals, Inc. | COM | 89237H209 | 140 | 84,003 | SH | DFND | 1 | 0 | 84,003 | 0 | |
| Vor Biopharma, Inc. | COM | 929033108 | 4,277 | 1,074,658 | SH | DFND | 1 | 0 | 1,074,658 | 0 | |
| Xencor, Inc. | COM | 98401F105 | 19,435 | 748,062 | SH | DFND | 1 | 0 | 748,062 | 0 | |
| SomaLogic, Inc. | COM | 83444K105 | 815 | 281,052 | SH | DFND | N/A | 0 | 281,052 | 0 | |