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Description of Business, Organization and Liquidity (Details)
$ / shares in Units, $ in Thousands
12 Months Ended
May 09, 2023
USD ($)
$ / shares
shares
Apr. 25, 2023
Jan. 04, 2023
USD ($)
shares
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Jul. 31, 2020
$ / shares
Subsidiary, Sale of Stock [Line Items]              
Reverse stock split, conversion ratio   0.5071          
Sale of stock, price (in dollars per share) | $ / shares             $ 0.00002
Underwriting discounts, commissions and offering costs       $ 47,354      
Temporary equity, convertible, conversion ratio 100.00%     100.00%      
Net losses       $ 381,641 $ 64,772 $ 41,839  
Research and development       355,886 55,632 38,230  
Payments to acquire in-process research and development       10,000 0 25,000  
Accumulated deficit       488,719 107,078    
Cash used in operating activities       169,705 $ 61,520 $ 4,979  
Cash, cash equivalents and short-term marketable securities       721,300      
Pierre Fabre              
Subsidiary, Sale of Stock [Line Items]              
Payments to acquire in-process research and development     $ 10,000 10,000      
ValenzaBio Asset Acquisition              
Subsidiary, Sale of Stock [Line Items]              
Issuance of common stock in connection with ValenzaBio acquisition (in shares) | shares     2,013,673        
Research and development     $ 123,100 $ 123,100      
ValenzaBio Asset Acquisition | Common Class A              
Subsidiary, Sale of Stock [Line Items]              
Issuance of common stock in connection with ValenzaBio acquisition (in shares) | shares     18,885,731        
IPO              
Subsidiary, Sale of Stock [Line Items]              
Number of shares issued in transaction (in shares) | shares 34,500,000            
Sale of stock, price (in dollars per share) | $ / shares $ 18.00            
Gross proceeds received on transaction $ 621,000            
Net proceeds received on transaction 573,600            
Underwriting discounts, commissions and offering costs $ 47,400            
Over-Allotment Option              
Subsidiary, Sale of Stock [Line Items]              
Number of shares issued in transaction (in shares) | shares 4,500,000