Exhibit 15

May 4, 2021

Securities and Exchange Commission 100 F Street, N.E.

Washington, DC 20549

Re:     JPMorgan Chase & Co.

    Registration Statements on Form S-3

    (No. 333-236659)

    (No. 333-236659-01)

    (No. 333-230098)

    Registration Statements on Form S-8

    (No. 333-219702)

    (No. 333-219701)

    (No. 333-219699)

    (No. 333-185584)

    (No. 333-185582)

    (No. 333-185581)

    (No. 333-175681)

    (No. 333-158325)

    (No. 333-142109)

    (No. 333-125827)

    (No. 333-112967)

Commissioners:

We are aware that our report dated May 4, 2021 on our review of interim financial information of JPMorgan Chase & Co. and its subsidiaries (the “Firm”), which appears in this Quarterly Report on Form 10-Q, is incorporated by reference in the Registration Statements of the Firm referred to above. Pursuant to Rule 436(c) under the Securities Act of 1933, such report should not be considered a part of such Registration Statements, and is not a report within the meaning of Sections 7 and 11 of that Act.

Very truly yours,

/s/ PricewaterhouseCoopers LLP

PricewaterhouseCoopers LLP, 300 Madison Avenue, New York, NY 10017