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ACCESSION NUMBER:		0000905729-16-000500

CONFORMED SUBMISSION TYPE:	S-4

PUBLIC DOCUMENT COUNT:		28

FILED AS OF DATE:		20160331

DATE AS OF CHANGE:		20160609


FILER:


	COMPANY DATA:	

		COMPANY CONFORMED NAME:			CHEMICAL FINANCIAL CORP

		CENTRAL INDEX KEY:			0000019612

		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]

		IRS NUMBER:				382022454

		STATE OF INCORPORATION:			MI

		FISCAL YEAR END:			1231



	FILING VALUES:

		FORM TYPE:		S-4

		SEC ACT:		1933 Act

		SEC FILE NUMBER:	333-210520

		FILM NUMBER:		161543786



	BUSINESS ADDRESS:	

		STREET 1:		235 E MAIN ST

		CITY:			MIDLAND

		STATE:			MI

		ZIP:			48640

		BUSINESS PHONE:		989-839-5350



	MAIL ADDRESS:	

		STREET 1:		235 E MAIN ST

		CITY:			MIDLAND

		STATE:			MI

		ZIP:			48640



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<DOCUMENT>
<TYPE>S-4
<SEQUENCE>1
<FILENAME>chems4_033116.htm
<DESCRIPTION>CHEMICAL FINANCIAL FORM S-4
<TEXT>
Document 1 - file: chems4_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>chemex51_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 5.1 TO FORM S-4
<TEXT>
Document 2 - file: chemex51_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-8.1
<SEQUENCE>3
<FILENAME>chemex81_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 8.1 TO FORM S-4
<TEXT>
Document 3 - file: chemex81_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-8.2
<SEQUENCE>4
<FILENAME>chemex82_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 8.2 TO FORM S-4
<TEXT>
Document 4 - file: chemex82_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.8
<SEQUENCE>5
<FILENAME>chemex108_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 10.8 TO FORM S-4
<TEXT>
Document 5 - file: chemex108_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.9
<SEQUENCE>6
<FILENAME>chemex109_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 10.9 TO FORM S-4
<TEXT>
Document 6 - file: chemex109_033116.htm

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<TYPE>EX-10.10
<SEQUENCE>7
<FILENAME>chemex1010_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 10.10 TO FORM S-4
<TEXT>
Document 7 - file: chemex1010_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>8
<FILENAME>chemex233_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 23.3 TO FORM S-4
<TEXT>
Document 8 - file: chemex233_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.4
<SEQUENCE>9
<FILENAME>chemex234_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 23.4 TO FORM S-4
<TEXT>
Document 9 - file: chemex234_033116.htm

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<TYPE>EX-24
<SEQUENCE>10
<FILENAME>chemex24_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 24 TO FORM S-4
<TEXT>
Document 10 - file: chemex24_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>11
<FILENAME>chemex991_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.1 TO FORM S-4
<TEXT>
Document 11 - file: chemex991_033116.htm

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<SEQUENCE>12
<FILENAME>soplogo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: soplogo.jpg

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<TYPE>EX-99.2
<SEQUENCE>13
<FILENAME>chemex992_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.2 TO FORM S-4
<TEXT>
Document 13 - file: chemex992_033116.htm

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<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>kbwlogo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: kbwlogo.jpg

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<SEQUENCE>15
<FILENAME>kbwsig.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 15 - file: kbwsig.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.3
<SEQUENCE>16
<FILENAME>chemex993_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.3 TO FORM S-4
<TEXT>
Document 16 - file: chemex993_033116.htm

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<TYPE>GRAPHIC
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<FILENAME>chempage1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 17 - file: chempage1.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>chempage2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 18 - file: chempage2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.4
<SEQUENCE>19
<FILENAME>chemex994_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.4 TO FORM S-4
<TEXT>
Document 19 - file: chemex994_033116.htm

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<TYPE>GRAPHIC
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<FILENAME>page1ex994.jpg
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<TEXT>
Document 20 - file: page1ex994.jpg

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<FILENAME>page2ex994.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 21 - file: page2ex994.jpg

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<TYPE>GRAPHIC
<SEQUENCE>22
<FILENAME>page3ex994.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 22 - file: page3ex994.jpg

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<TYPE>EX-99.5
<SEQUENCE>23
<FILENAME>chemex995_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.5 TO FORM S-4
<TEXT>
Document 23 - file: chemex995_033116.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.6
<SEQUENCE>24
<FILENAME>chemex996_033116.htm
<DESCRIPTION>CHEMICAL EXHIBIT 99.6 TO FORM S-4
<TEXT>
Document 24 - file: chemex996_033116.htm

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<TYPE>GRAPHIC
<SEQUENCE>26
<FILENAME>chemlogo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 26 - file: chemlogo.jpg

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<SEQUENCE>27
<FILENAME>talmerlogo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 27 - file: talmerlogo.jpg

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<SEQUENCE>28
<FILENAME>image_001.jpg
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<TEXT>
Document 28 - file: image_001.jpg

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<DOCUMENT>
<TYPE>COVER
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<FILENAME>filename29.htm
<TEXT>
Document 29 - file: filename29.htm

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