The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AFFIMED N V | COM | N01045108 | 1,394 | 676,675 | SH | SOLE | 676,675 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 4,856 | 718,394 | SH | SOLE | 718,394 | 0 | 0 | ||
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 7,325 | 6,720,148 | SH | SOLE | 6,720,148 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 7,066 | 676,849 | SH | SOLE | 676,849 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 5,482 | 435,117 | SH | SOLE | 435,117 | 0 | 0 | ||
| BIOGEN INC | COM | 09062X103 | 20,025 | 75,000 | SH | SOLE | 75,000 | 0 | 0 | ||
| BURNING ROCK BIOTECH LTD | SPONSORED ADS | 12233L107 | 16,022 | 6,703,863 | SH | SOLE | 6,703,863 | 0 | 0 | ||
| CABALETTA BIO INC | COM | 12674W109 | 343 | 527,805 | SH | SOLE | 527,805 | 0 | 0 | ||
| CATALYST BIOSCIENCES INC | COM NEW | 14888D208 | 45 | 90,188 | SH | SOLE | 90,188 | 0 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 44,980 | 1,600,127 | SH | SOLE | 1,600,127 | 0 | 0 | ||
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 | 2,941 | 731,521 | SH | SOLE | 731,521 | 0 | 0 | ||
| COGENT BIOSCIENCES INC | COM | 19240Q201 | 14,699 | 985,155 | SH | SOLE | 985,155 | 0 | 0 | ||
| CONCERT PHARMACEUTICALS INC | COM | 206022105 | 11,209 | 1,673,041 | SH | SOLE | 1,673,041 | 0 | 0 | ||
| CONNECT BIOPHARMA HLDGS LTD | ADS | 207523101 | 954 | 739,649 | SH | SOLE | 739,649 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 8,936 | 131,220 | SH | SOLE | 131,220 | 0 | 0 | ||
| GOSSAMER BIO INC | COM | 38341P102 | 4,628 | 386,349 | SH | SOLE | 386,349 | 0 | 0 | ||
| GSK PLC | SPONSORED ADR | 37733W204 | 14,715 | 500,000 | SH | SOLE | 500,000 | 0 | 0 | ||
| LIQUIDIA CORPORATION | COM NEW | 53635D202 | 9,207 | 1,692,402 | SH | SOLE | 1,692,402 | 0 | 0 | ||
| LIQUIDIA CORPORATION | COM NEW | 53635D202 | 13 | 507,700 | SH | Call | SOLE | 507,700 | 0 | 0 | |
| NATERA INC | COM | 632307104 | 88,445 | 2,018,360 | SH | SOLE | 2,018,360 | 0 | 0 | ||
| NEOLEUKIN THERAPEUTICS INC | COM | 64049K104 | 77 | 120,368 | SH | SOLE | 120,368 | 0 | 0 | ||
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | 3,863 | 1,399,633 | SH | SOLE | 1,399,633 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 4,377 | 519,212 | SH | SOLE | 519,212 | 0 | 0 | ||
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 1,327 | 559,769 | SH | SOLE | 559,769 | 0 | 0 | ||
| RELMADA THERAPEUTICS INC | COM | 75955J402 | 803 | 300,000 | SH | Put | SOLE | 300,000 | 0 | 0 | |
| SANOFI | SPONSORED ADR | 80105N105 | 22,812 | 600,000 | SH | SOLE | 600,000 | 0 | 0 | ||
| SERES THERAPEUTICS INC | COM | 81750R102 | 4,962 | 772,820 | SH | SOLE | 772,820 | 0 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 54,618 | 2,272,915 | SH | SOLE | 2,272,915 | 0 | 0 | ||
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | 10,268 | 416,729 | SH | SOLE | 416,729 | 0 | 0 | ||
| TRICIDA INC | COM | 89610F101 | 338 | 260,000 | SH | Call | SOLE | 260,000 | 0 | 0 | |
| TRICIDA INC | COM | 89610F101 | 122 | 97,600 | SH | Put | SOLE | 97,600 | 0 | 0 | |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 31,618 | 151,009 | SH | SOLE | 151,009 | 0 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 16,767 | 698,638 | SH | SOLE | 698,638 | 0 | 0 | ||
| VERA THERAPEUTICS INC | CL A | 92337R101 | 32,736 | 1,536,181 | SH | SOLE | 1,536,181 | 0 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 20,510 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 5,045 | 1,397,479 | SH | SOLE | 1,397,479 | 0 | 0 | ||
| XENON PHARMACEUTICALS INC | COM | 98420N105 | 1,039 | 28,792 | SH | SOLE | 28,792 | 0 | 0 | ||