Exhibit 5.1

June 7, 2024

DraftKings Inc.

222 Berkeley Street, 5^th Floor
Boston, Massachusetts 02116

Re: Registration Statement on Form S-3 (Reg. No. 333-280043)

Ladies and Gentlemen:

We have acted as special Nevada counsel to DraftKings Inc., a Nevada corporation (the “Company”), in connection with the Company’s registration of 7,507,817 shares of the Company’s Class A common stock, par value $0.0001 per share (the “Resale Shares”), covered by the above-referenced automatic shelf registration statement (including the prospectus contained therein, the “Registration Statement”), filed by the Company with the U.S. Securities and Exchange Commission (the “Commission”) under the Securities Act of 1933, as amended (the “Securities Act”), together with the Prospectus Supplement, dated June 7, 2024 (the “Prospectus Supplement”), filed with the Commission pursuant to Rule 424(b)(7) under the Securities Act, relating to the resale of the Resale Shares by the selling securityholders named in the Prospectus Supplement. The Resale Shares were issued pursuant to that certain Agreement and Plan of Merger and Plan of Reorganization, dated as of February 11, 2024 (the “Merger Agreement”), by and among the Company, DraftKings Holdings Inc., Fortune Merger Sub Inc., Fortune Merger Sub LLC, JackPocket Inc., and Shareholder Representative Services LLC.

In connection with our representation of the Company and the preparation of this opinion letter, we have examined, considered and relied upon the following documents (collectively, the “Documents”):

1.              the Registration Statement and all amendments thereto, and the related form of prospectus contained therein, in the form in which it was transmitted to the Commission for filing on June 7, 2024;

2.              the Prospectus Supplement, in the form transmitted to the Commission for filing on June 7, 2024 pursuant to Rule 424(b)(7) under the Securities Act;

3.              the Merger Agreement;

4.              the Company’s Amended and Restated Articles of Incorporation, as filed with the Secretary of State of the State of Nevada;

5.              the Company’s Amended and Restated Bylaws;

6.              resolutions adopted by the Board of Directors of the Company in respect of the Merger Agreement and the issuance of the Resale Shares; and

7.              such other documents and matters of law as we have considered necessary or appropriate for the expression of the opinions contained herein.

Greenberg Traurig, LLP | Attorneys at Law

10845 Griffith Peak Drive  |  Suite 600  |  Las Vegas, Nevada 89135  |  T +1 702.792.3773  |  F +1 702.792.9002

www.gtlaw.com

DraftKings Inc.

June 7, 2024

Page 2

In rendering the opinions set forth below, we have assumed without investigation the following: (i) the genuineness of all signatures and the authenticity of all Documents submitted to us as originals, the conformity to authentic original documents of all Documents submitted to us as copies and the veracity of the Documents; (ii) each individual executing any of the Documents, whether on behalf of such individual or another person, is legally competent to do so; (iii) each of the parties (other than the Company) executing any of the Documents has duly and validly executed and delivered each of the Documents to which such party is a signatory; and (iv) the obligations of each party set forth in the Merger Agreement are valid and binding obligations of such party and are enforceable against such party in accordance with all stated terms.

As to various questions of fact material to this opinion letter, we have relied, to the extent we deemed reasonably appropriate, upon representations of officers or directors of the Company and upon documents, records and instruments furnished to us by the Company, without independently checking or verifying the accuracy of such documents, records and instruments.

Based upon the foregoing, and subject to the qualifications, assumptions and limitations set forth herein, we are of the opinion that the Resale Shares have been duly authorized and validly issued and are fully paid and nonassessable.

This opinion letter is limited to the matters stated herein, and no opinions may be implied or inferred beyond the matters expressly stated herein. The opinions expressed herein are as of the date hereof, and we assume no obligation to update or supplement such opinions to reflect any facts or circumstances that may hereafter come to our attention or any changes in law that may hereafter occur. We do not express any opinion herein concerning any law other than the laws of the State of Nevada.

This opinion letter is being furnished to you for submission to the Commission as an exhibit to the Company’s Current Report on Form 8-K relating to the registration of the Resale Shares (the “Current Report”), which is incorporated by reference in the Registration Statement. We hereby consent to the filing of this opinion letter as an exhibit to the Current Report and such incorporation by reference into the Registration Statement, of which the Prospectus Supplement forms a part, and to the use of the name of our firm therein. In giving this consent, we do not admit that we are within the category of persons whose consent is required by Section 7 of the Securities Act or the rules and regulations of the Commission promulgated thereunder.

Sincerely,

/s/ Greenberg Traurig, LLP

GREENBERG TRAURIG, LLP

Greenberg Traurig, LLP | Attorneys at Law

www.gtlaw.com