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Property, plant and equipment, net - Summary of Property, Plant and Equipment, Net (Detail) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment $ 63,964 $ 115,061
Less accumulated depreciation and amortization (27,245) (56,911)
Property, plant and equipment, net 36,719 58,150
Computer equipment and software    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 4,965 6,156
Office equipment    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 6,330 6,726
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 4,329 43,209
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment 48,340 58,832
Construction-in-progress    
Property, Plant and Equipment [Line Items]    
Total property, plant and equipment $ 0 $ 138