Accrued expenses and other current liabilities (Detail) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Royalties	$ 13,753	$ 13,094
Employee compensation	10,308	14,845
Manufacturing costs	4,748	17,962
Property, plant, and equipment	1,407	1,498
Clinical and contract research organization costs	1,555	1,619
Professional fees	336	239
Collaboration research costs	568	2,005
Other	3,432	3,416
Total accrued expenses and other current liabilities	$ 36,107	$ 54,678