Property, plant and equipment, net - Summary of Property, Plant and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 74,991	$ 174,062
Less accumulated depreciation and amortization	(40,078)	(30,037)
Property, plant and equipment, net	34,913	144,025
Land
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	0	1,210
Building
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	0	15,745
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	5,260	6,503
Office equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	6,080	6,588
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	31,710	24,080
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	28,479	28,305
Construction-in-progress
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 3,462	$ 91,631