Consolidated and Combined Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue:
Collaborative arrangement revenue	$ 26,921	$ 115,594	$ 5,740
Total revenues	54,522	248,122	44,296
Operating expenses:
Research and development	261,937	296,467	297,645
Selling, general and administrative	93,506	90,897	81,646
Share of collaboration loss	10,071	0	0
Cost of royalty and other revenue	2,517	5,396	2,978
Change in fair value of contingent consideration	439	(6,468)	2,747
Total operating expenses	368,470	386,292	385,016
Loss from operations	(313,948)	(138,170)	(340,720)
Interest income, net	88	0	0
Other income, net	21,647	18,056	20,126
Loss before income taxes	(292,213)	(120,114)	(320,594)
Income tax (expense) benefit	0	0	0
Net loss	$ (292,213)	$ (120,114)	$ (320,594)
Net loss per share - basic (in dollars per share)	$ (12.44)	$ (5.14)	$ (13.72)
Net loss per share - diluted (in dollars per share)	$ (12.44)	$ (5.14)	$ (13.72)
Weighted-average number of common shares used in computing net loss per share - basic	23,499	23,369	23,369
Weighted-average number of common shares used in computing net loss per share - diluted	23,499	23,369	23,369
Other comprehensive loss:
Other comprehensive loss, net of tax benefit (expense) of $0.0 million, $0.0 million, and $0.0 million for the years ended December 31, 2021, 2020 and 2019, respectively	$ (712)	$ 0	$ 0
Comprehensive loss	(292,925)	(120,114)	(320,594)
Service revenue
Revenue:
Revenue	21,381	111,452	30,351
Royalty and other revenue
Revenue:
Revenue	$ 6,220	$ 21,076	$ 8,205