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Summary of significant accounting policies and basis of presentation - Narrative (Detail)
12 Months Ended
Dec. 31, 2021
USD ($)
segment
shares
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
USD ($)
Nov. 04, 2021
USD ($)
Nov. 03, 2021
shares
Restricted Cash and Cash Equivalents Items [Line Items]          
Transfers from bluebird bio $ 354,889,000 $ 90,054,000 $ 267,722,000    
Net assets       $ 384,500,000  
Number of operating segments | segment 1        
Accumulated goodwill impairment loss $ 0        
Interest income $ 88,000 $ 0 0    
Common stock, shares outstanding (in shares) | shares 23,585,000 0     0
Restricted cash included in restricted cash and other non-current assets $ 32,852,000 $ 0 $ 0    
Letter of credit          
Restricted Cash and Cash Equivalents Items [Line Items]          
Restricted cash included in restricted cash and other non-current assets $ 30,000,000