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Property, plant and equipment, net (Tables)
12 Months Ended
Dec. 31, 2021
Property, Plant and Equipment [Abstract]  
Summary of Property, Plant and Equipment, Net
Property, plant and equipment, net, consists of the following (in thousands):
As of December 31,
20212020
Land$— $1,210 
Building— 15,745 
Computer equipment and software5,260 6,503 
Office equipment6,080 6,588 
Laboratory equipment31,710 24,080 
Leasehold improvements28,479 28,305 
Construction-in-progress3,462 91,631 
Total property, plant and equipment74,991 174,062 
Less accumulated depreciation and amortization(40,078)(30,037)
Property, plant and equipment, net$34,913 $144,025