STOCK-BASED COMPENSATION (Tables)

12 Months Ended

Dec. 31, 2022

Share-Based Payment Arrangement [Abstract]

SCHEDULE OF SHARE BASED COMPENSATION

A summary of the stock option activity during the year ended December 31, 2022, is presented in the table below:

				Weighted average
	Number of options			Exercise price		Remaining contractual life (in years)		Intrinsic value
Outstanding as of January 1, 2022		1,174,660		$	17.10		9.1	$	241,103
Granted		621,450		$	4.04		-	$	-
Forfeited and cancelled		(123,237	)	$	6.72		-	$	-
Outstanding as of December 31, 2022		1,672,873		$	13.01		8.5	$	-
Exercisable as of December 31, 2022		601,361		$	24.45		7.8	$	-
Vested and expected to vest as of December 31, 2022		1,672,873		$	13.01		8.5	$	-

SCHEDULE OF STOCK BASED COMPENSATION EXPENSES

	For the year ended December 31,
	2022		2021
Research and development	$	709,527	$	387,111
General and administrative		2,247,722		1,123,147
Total stock-based compensation expense	$	2,957,249	$	1,510,258

SCHEDULE OF WEIGHTED AVERAGE INPUTS USED TO MEASURE VALUE OF OPTIONS GRANTED

	2022			2021
Stock price	$	4.04		$	8.80
Exercise price	$	4.04		$	8.80
Expected term (in years)		5.83			5.73
Volatility		106.6	%		103.3	%
Risk free rate		2.2	%		0.7	%
Dividend yield		0.0	%		0.0	%

SCHEDULE OF EXERCISE PRICE OF OUTSTANDING STOCK OPTIONS

Exercise price	Options outstanding
$0.01 - $8.00		632,175
$8.01 - $16.00		1,006,000
$16.01 or higher		34,698
Total		1,672,873